DE60144383D1 - Methoden zur verminderung oder verhinderung von schmerzen mit spicamycin-derivaten - Google Patents

Methoden zur verminderung oder verhinderung von schmerzen mit spicamycin-derivaten

Info

Publication number
DE60144383D1
DE60144383D1 DE60144383T DE60144383T DE60144383D1 DE 60144383 D1 DE60144383 D1 DE 60144383D1 DE 60144383 T DE60144383 T DE 60144383T DE 60144383 T DE60144383 T DE 60144383T DE 60144383 D1 DE60144383 D1 DE 60144383D1
Authority
DE
Germany
Prior art keywords
preventing
methods
pain
spicamycin derivatives
spicamycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60144383T
Other languages
English (en)
Inventor
David Borsook
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Application granted granted Critical
Publication of DE60144383D1 publication Critical patent/DE60144383D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
DE60144383T 2000-09-20 2001-09-20 Methoden zur verminderung oder verhinderung von schmerzen mit spicamycin-derivaten Expired - Lifetime DE60144383D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23438200P 2000-09-20 2000-09-20
PCT/US2001/029371 WO2002024146A2 (en) 2000-09-20 2001-09-20 Methods of decreasing or preventing pain using spicamycin derivatives

Publications (1)

Publication Number Publication Date
DE60144383D1 true DE60144383D1 (de) 2011-05-19

Family

ID=22881151

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60144383T Expired - Lifetime DE60144383D1 (de) 2000-09-20 2001-09-20 Methoden zur verminderung oder verhinderung von schmerzen mit spicamycin-derivaten

Country Status (9)

Country Link
US (3) US7196071B2 (de)
EP (2) EP1328236B1 (de)
JP (1) JP5016777B2 (de)
AT (1) ATE504302T1 (de)
AU (1) AU2001291133A1 (de)
CA (1) CA2425172C (de)
DE (1) DE60144383D1 (de)
ES (1) ES2365473T3 (de)
WO (1) WO2002024146A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7196071B2 (en) * 2000-09-20 2007-03-27 The General Hospital Corporation Methods of decreasing or preventing pain using spicamycin derivatives
US7906487B2 (en) * 2002-05-22 2011-03-15 Fushimi Pharmaceutical Co., Ltd. Method of utilizing physiological activity of rare saccharide and composition containing rare saccharide
US7860552B2 (en) * 2004-10-01 2010-12-28 The Mclean Hospital Corporation CNS assay for prediction of therapeutic efficacy for neuropathic pain and other functional illnesses
JP5116071B2 (ja) 2005-07-20 2013-01-09 帝國製薬株式会社 Ｄ−アロースおよびｄ−プシコースの抗神経因性疼痛効果の利用
ES2567455T3 (es) * 2008-10-10 2016-04-22 Dara Biosciences, Inc. Nanoemulsiones que comprenden derivados de espicamicina para su uso en el tratamiento del dolor
CN104822369A (zh) 2012-08-09 2015-08-05 达拉生物科学公司 包含穗霉素衍生物的组合物及其使用方法
US10262107B1 (en) * 2013-03-15 2019-04-16 Bao Tran Pharmacogenetic drug interaction management system
WO2015061481A1 (en) 2013-10-23 2015-04-30 Dara Biosciences, Inc. Methods of treating liquid tumors using compositions comprising spicamycin derivatives
US10732507B2 (en) 2015-10-26 2020-08-04 Esko-Graphics Imaging Gmbh Process and apparatus for controlled exposure of flexographic printing plates and adjusting the floor thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US5252463A (en) * 1990-06-22 1993-10-12 The Du Pont Merck Pharmaceutical Company Clipsin, a chymotrypsin-like protease and method of using same
JP2783722B2 (ja) 1991-07-12 1998-08-06 麒麟麦酒株式会社 スピカマイシン誘導体およびそれを含む抗腫瘍剤
US5824645A (en) 1991-12-30 1998-10-20 Neurex Corporation Method of treating inflammation
US6013853A (en) 1992-02-14 2000-01-11 The University Of Texas System Continuous release polymeric implant carrier
US5905069A (en) * 1998-01-26 1999-05-18 The General Hospital Corporation Methods of decreasing or preventing pain using spicamycin or derivatives thereof
US7196071B2 (en) * 2000-09-20 2007-03-27 The General Hospital Corporation Methods of decreasing or preventing pain using spicamycin derivatives

Also Published As

Publication number Publication date
JP2004537494A (ja) 2004-12-16
US20070161597A1 (en) 2007-07-12
EP1328236B1 (de) 2011-04-06
EP2305264A1 (de) 2011-04-06
US7632825B2 (en) 2009-12-15
US20040038927A1 (en) 2004-02-26
US7196071B2 (en) 2007-03-27
EP1328236A2 (de) 2003-07-23
JP5016777B2 (ja) 2012-09-05
AU2001291133A1 (en) 2002-04-02
WO2002024146A2 (en) 2002-03-28
ES2365473T3 (es) 2011-10-06
US7375094B2 (en) 2008-05-20
CA2425172C (en) 2011-02-01
US20080207557A1 (en) 2008-08-28
ATE504302T1 (de) 2011-04-15
EP1328236A4 (de) 2005-10-26
WO2002024146A3 (en) 2003-05-22
WO2002024146A9 (en) 2004-05-13
CA2425172A1 (en) 2002-03-28

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