DE60143905D1 - Phtalazinon derivate - Google Patents

Phtalazinon derivate

Info

Publication number
DE60143905D1
DE60143905D1 DE60143905T DE60143905T DE60143905D1 DE 60143905 D1 DE60143905 D1 DE 60143905D1 DE 60143905 T DE60143905 T DE 60143905T DE 60143905 T DE60143905 T DE 60143905T DE 60143905 D1 DE60143905 D1 DE 60143905D1
Authority
DE
Germany
Prior art keywords
phtalazinone
derivatives
phtalazinone derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60143905T
Other languages
English (en)
Inventor
Niall Morrison B Martin
Graeme Cameron M Smith
Charles Richard White
Roger Frank Newton
Diane Gillian Douglas
Penny Jane Eversley
Julia Vile
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kudos Pharmaceuticals Ltd
Maybridge Ltd
Original Assignee
Kudos Pharmaceuticals Ltd
Maybridge Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kudos Pharmaceuticals Ltd, Maybridge Ltd filed Critical Kudos Pharmaceuticals Ltd
Priority claimed from PCT/GB2001/004729 external-priority patent/WO2002036576A1/en
Application granted granted Critical
Publication of DE60143905D1 publication Critical patent/DE60143905D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60143905T 2000-10-30 2001-10-25 Phtalazinon derivate Expired - Lifetime DE60143905D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0026505.8A GB0026505D0 (en) 2000-10-30 2000-10-30 Phthalazinone derivatives
US27506601P 2001-03-12 2001-03-12
PCT/GB2001/004729 WO2002036576A1 (en) 2000-10-30 2001-10-25 Phthalazinone derivatives

Publications (1)

Publication Number Publication Date
DE60143905D1 true DE60143905D1 (de) 2011-03-03

Family

ID=9902199

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60143905T Expired - Lifetime DE60143905D1 (de) 2000-10-30 2001-10-25 Phtalazinon derivate

Country Status (8)

Country Link
JP (1) JP4903355B2 (de)
AT (1) ATE496034T1 (de)
DE (1) DE60143905D1 (de)
DK (1) DK1330442T3 (de)
ES (1) ES2359131T3 (de)
GB (1) GB0026505D0 (de)
PT (1) PT1330442E (de)
ZA (1) ZA200302112B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2384776C (en) * 2000-10-30 2006-02-03 Kudos Pharm Ltd Phthalazinone derivatives
AU2005276229A1 (en) * 2004-08-26 2006-03-02 Kudos Pharmaceuticals Limited 4-heteroarylmethyl substituted phthalazinone derivatives
GB0428111D0 (en) * 2004-12-22 2005-01-26 Kudos Pharm Ltd Pthalazinone derivatives
PL2120579T3 (pl) * 2006-12-28 2014-04-30 Abbvie Inc Inhibitory polimerazy poli(ADP-rybozy)
WO2012014221A1 (en) * 2010-07-27 2012-02-02 Cadila Healthcare Limited Substituted 4-(4-fluoro-3-(piperazine-1- carbonyl)benzyl)phthalazin-1(2h)-one derivatives as poly (adp-ribose) polymerase- 1 inhibitors
CN103130723B (zh) * 2011-11-30 2015-01-14 成都地奥制药集团有限公司 一种多聚(adp-核糖)聚合酶抑制剂
CN105307655B (zh) * 2013-03-13 2019-05-03 弗拉特利发现实验室有限责任公司 哒嗪酮化合物及其用于制备治疗囊肿状纤维化的药物的应用

Also Published As

Publication number Publication date
ATE496034T1 (de) 2011-02-15
PT1330442E (pt) 2011-04-20
ZA200302112B (en) 2004-02-20
JP2004513121A (ja) 2004-04-30
GB0026505D0 (en) 2000-12-13
JP4903355B2 (ja) 2012-03-28
ES2359131T3 (es) 2011-05-18
DK1330442T3 (da) 2011-04-11

Similar Documents

Publication Publication Date Title
DE60009147D1 (de) Admantan derivate
DK1292604T3 (da) 2-Aminocarbonyl-9H-purinderivater
DE60120366D1 (de) Arylkondensiete azapolycyclische derivate
ATE288437T1 (de) Tetrahydro-heterocycloazepinyl-pyrimidin-deriva e
DE60105020D1 (de) 6-phenylpyrrolopyrimidindion derivate
ATE298332T1 (de) Decahydro-isochinolinderivate
ATE273962T1 (de) 5-phenyl-pyrimidine derivate
DK1280809T3 (da) Antitumorecteinascidinderivater
DK1571140T3 (da) Substituerede C-cyjklohexylmethylamin-derivater
AR028602A1 (es) Derivados de pirrol
AR028282A1 (es) Derivados de aminofenil pirimidona
DE60025918D1 (de) 4-phenyl-pyrimidine derivate
DK1322593T3 (da) O-substituerede-6-methyl-tramadol-derivater
ATE282021T1 (de) Substituierte aminomethyl-phenyl- cyclohexanderivate
ATE280752T1 (de) Aminomethyl-phenyl-cyclohexanonderivate
DE60143905D1 (de) Phtalazinon derivate
DE50112454D1 (de) Substituierte 5-amino-1-penten-3-ol-derivate
ATE269316T1 (de) 2-phenylpyran-4-on derivate
ATE374776T1 (de) Pyrrolotriazolopyrimidinonderivate
DK1246793T3 (da) Substituerede aminomethyl-phenyl-cyclohexanderivater