DE60134931D1 - Phosphatidyl-L-serin und Phosphatidylsäure zur Behandlung von Depression und Stresszuständen - Google Patents
Phosphatidyl-L-serin und Phosphatidylsäure zur Behandlung von Depression und StresszuständenInfo
- Publication number
- DE60134931D1 DE60134931D1 DE60134931T DE60134931T DE60134931D1 DE 60134931 D1 DE60134931 D1 DE 60134931D1 DE 60134931 T DE60134931 T DE 60134931T DE 60134931 T DE60134931 T DE 60134931T DE 60134931 D1 DE60134931 D1 DE 60134931D1
- Authority
- DE
- Germany
- Prior art keywords
- serine
- phosphatidic acid
- lecithin
- phosphatidyl
- phosphatidy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- PORPENFLTBBHSG-MGBGTMOVSA-N 1,2-dihexadecanoyl-sn-glycerol-3-phosphate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=O)OC(=O)CCCCCCCCCCCCCCC PORPENFLTBBHSG-MGBGTMOVSA-N 0.000 title abstract 6
- 229960001153 serine Drugs 0.000 title abstract 6
- 208000020401 Depressive disease Diseases 0.000 title 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 3
- 229940067606 lecithin Drugs 0.000 abstract 3
- 235000010445 lecithin Nutrition 0.000 abstract 3
- 239000000787 lecithin Substances 0.000 abstract 3
- 230000002996 emotional effect Effects 0.000 abstract 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 abstract 2
- 230000003340 mental effect Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 150000003904 phospholipids Chemical class 0.000 abstract 2
- 239000002994 raw material Substances 0.000 abstract 2
- JQWAHKMIYCERGA-UHFFFAOYSA-N (2-nonanoyloxy-3-octadeca-9,12-dienoyloxypropoxy)-[2-(trimethylazaniumyl)ethyl]phosphinate Chemical compound CCCCCCCCC(=O)OC(COP([O-])(=O)CC[N+](C)(C)C)COC(=O)CCCCCCCC=CCC=CCCCCC JQWAHKMIYCERGA-UHFFFAOYSA-N 0.000 abstract 1
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 abstract 1
- 240000002791 Brassica napus Species 0.000 abstract 1
- 235000004977 Brassica sinapistrum Nutrition 0.000 abstract 1
- 102000011420 Phospholipase D Human genes 0.000 abstract 1
- 108090000553 Phospholipase D Proteins 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 125000005313 fatty acid group Chemical group 0.000 abstract 1
- 229960000890 hydrocortisone Drugs 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000036651 mood Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000000697 serotonin reuptake Effects 0.000 abstract 1
- 229940083466 soybean lecithin Drugs 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL139224A IL139224A (en) | 2000-10-23 | 2000-10-23 | Anti depressant, stress suppressor and mood improver |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60134931D1 true DE60134931D1 (de) | 2008-09-04 |
Family
ID=11074750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60134931T Expired - Lifetime DE60134931D1 (de) | 2000-10-23 | 2001-06-28 | Phosphatidyl-L-serin und Phosphatidylsäure zur Behandlung von Depression und Stresszuständen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6410522B1 (de) |
| EP (1) | EP1201244B1 (de) |
| AT (1) | ATE401898T1 (de) |
| CA (1) | CA2352528C (de) |
| DE (1) | DE60134931D1 (de) |
| DK (1) | DK1201244T3 (de) |
| ES (1) | ES2309021T3 (de) |
| HK (1) | HK1046237B (de) |
| IL (1) | IL139224A (de) |
| PT (1) | PT1201244E (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7892586B2 (en) | 2001-02-22 | 2011-02-22 | Suzanne Jaffe Stillman | Water containing soluble fiber |
| US8178150B2 (en) | 2000-02-22 | 2012-05-15 | Suzanne Jaffe Stillman | Water containing soluble fiber |
| WO2001068104A1 (en) * | 2000-03-16 | 2001-09-20 | The Mclean Hospital Corporation | Compounds for the treatment of psychiatric or substance abuse disorders |
| IL150240A (en) * | 2002-06-16 | 2005-07-25 | Lipogen Ltd | Infant formula supplemented with phospholipids |
| US20050129738A1 (en) * | 2002-06-16 | 2005-06-16 | Lipogen Ltd. | Infant formula supplemented with phospholipids |
| US6878532B1 (en) | 2003-04-28 | 2005-04-12 | Sioux Biochemical, Inc. | Method of producing phosphatidylserine |
| WO2005044176A2 (en) * | 2003-11-10 | 2005-05-19 | Lipogen Ltd. | Compositions containing phosphatidic acid, methods of use thereof, methods of manufacture thereof, and articles of manufacture containing same |
| GB0400031D0 (en) | 2004-01-03 | 2004-02-04 | Univ Sheffield | Depression treatment |
| US7737128B2 (en) * | 2004-06-10 | 2010-06-15 | The Mclean Hospital Corporation | Pyrimidines, such as uridine, in treatments for patients with bipolar disorder |
| EP1765364A4 (de) * | 2004-06-10 | 2010-09-22 | Mclean Hospital Corp | Pyrimidine, wie z:b: cytidin, bei der behandlung von patienten mit bipolaren störungen |
| WO2006020703A1 (en) * | 2004-08-11 | 2006-02-23 | The Mclean Hospital Corporation | Compounds for the treatment of marihuana dependence, withdrawal, and usage |
| EP1896074A4 (de) * | 2005-05-25 | 2009-04-22 | Liponex Inc | Pharmazeutische zusammensetzungen zur behandlung oder prävention von koronararterienkrankheit |
| IL182372A0 (en) * | 2007-04-01 | 2008-01-20 | Enzymotec Ltd | Compositions containing phosphatidylserine in treating diabetes-associated conditions |
| US8846338B2 (en) | 2008-08-07 | 2014-09-30 | Lipogen Ltd. | Processes for the preparation of phosphatides |
| US8546104B2 (en) | 2008-08-07 | 2013-10-01 | Lipogen Ltd. | Processes for the preparation of phosphatide salts |
| US20100041621A1 (en) * | 2008-08-15 | 2010-02-18 | Perry Renshaw | Methods and compositions for improving cognitive performance |
| US9326961B2 (en) * | 2010-02-26 | 2016-05-03 | Coape, Ltd | Diet and methods for improving learning capacity, mood and behavior in mammals |
| US20130064804A1 (en) * | 2011-09-14 | 2013-03-14 | Naidu Lp | BIO-REPLENISHMENT (BioRep) FOR IMPROVING SLEEP ARCHITECTURE |
| ES2587932T3 (es) * | 2013-02-22 | 2016-10-27 | Lipogen Ltd. | Composiciones para su uso en el alivio de los síntomas asociados con el síndrome premenstrual y el trastorno disfórico premenstrual |
| EP2881104A1 (de) | 2013-12-05 | 2015-06-10 | Lonza Ltd | Verwendung von Zusammensetzungen mit Phosphatidylserin und Phosphatidsäure und/oder Salzen davon zur Verringerung oder Vorbeugung von Schwitzen |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4117629A1 (de) * | 1991-05-29 | 1992-12-03 | Max Planck Gesellschaft | Phospatidylserine |
| US5700668A (en) * | 1995-12-08 | 1997-12-23 | Italfarmaco Sud S.P.A. | Process for the industrial preparation of phosphatidylserine |
| IL118180A (en) * | 1996-05-08 | 2000-12-06 | Modus Biolog Membranes Ltd | Pharmaceutical compositions comprising a phosphatidic acid (PA) enriched natural phospholipid preparation and the production of such preparation |
-
2000
- 2000-10-23 IL IL139224A patent/IL139224A/en active IP Right Grant
-
2001
- 2001-06-28 EP EP01114833A patent/EP1201244B1/de not_active Expired - Lifetime
- 2001-06-28 PT PT01114833T patent/PT1201244E/pt unknown
- 2001-06-28 ES ES01114833T patent/ES2309021T3/es not_active Expired - Lifetime
- 2001-06-28 DE DE60134931T patent/DE60134931D1/de not_active Expired - Lifetime
- 2001-06-28 AT AT01114833T patent/ATE401898T1/de active
- 2001-06-28 DK DK01114833T patent/DK1201244T3/da active
- 2001-07-03 US US09/897,034 patent/US6410522B1/en not_active Expired - Lifetime
- 2001-07-06 CA CA002352528A patent/CA2352528C/en not_active Expired - Fee Related
-
2002
- 2002-10-15 HK HK02107472.0A patent/HK1046237B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK1201244T3 (da) | 2008-11-17 |
| IL139224A (en) | 2009-09-01 |
| EP1201244A2 (de) | 2002-05-02 |
| HK1046237A1 (en) | 2003-01-03 |
| HK1046237B (zh) | 2009-04-09 |
| EP1201244A3 (de) | 2003-12-10 |
| EP1201244B1 (de) | 2008-07-23 |
| US20020072508A1 (en) | 2002-06-13 |
| US6410522B1 (en) | 2002-06-25 |
| ES2309021T3 (es) | 2008-12-16 |
| CA2352528C (en) | 2005-12-06 |
| CA2352528A1 (en) | 2002-04-23 |
| ATE401898T1 (de) | 2008-08-15 |
| PT1201244E (pt) | 2008-09-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |