DE60134849D1 - Ausrichtung eines optischen detektionssystems mit einem kapillarkanal in einem mikrofluiden laborchip - Google Patents

Ausrichtung eines optischen detektionssystems mit einem kapillarkanal in einem mikrofluiden laborchip

Info

Publication number
DE60134849D1
DE60134849D1 DE60134849T DE60134849T DE60134849D1 DE 60134849 D1 DE60134849 D1 DE 60134849D1 DE 60134849 T DE60134849 T DE 60134849T DE 60134849 T DE60134849 T DE 60134849T DE 60134849 D1 DE60134849 D1 DE 60134849D1
Authority
DE
Germany
Prior art keywords
microfluid
orientation
detection system
optical detection
capillary channel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60134849T
Other languages
English (en)
Inventor
Kevin Maher
Torleif Ove Bjornson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monogram Biosciences Inc
Original Assignee
Aclara Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aclara Biosciences Inc filed Critical Aclara Biosciences Inc
Application granted granted Critical
Publication of DE60134849D1 publication Critical patent/DE60134849D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
DE60134849T 2000-05-19 2001-05-17 Ausrichtung eines optischen detektionssystems mit einem kapillarkanal in einem mikrofluiden laborchip Expired - Lifetime DE60134849D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20552000P 2000-05-19 2000-05-19
PCT/US2001/016167 WO2001090726A2 (en) 2000-05-19 2001-05-17 Optical alignment in capillary detection using capillary wall scatter

Publications (1)

Publication Number Publication Date
DE60134849D1 true DE60134849D1 (de) 2008-08-28

Family

ID=22762532

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60134849T Expired - Lifetime DE60134849D1 (de) 2000-05-19 2001-05-17 Ausrichtung eines optischen detektionssystems mit einem kapillarkanal in einem mikrofluiden laborchip

Country Status (6)

Country Link
US (1) US6515753B2 (de)
EP (1) EP1285255B1 (de)
JP (1) JP2003534545A (de)
AU (1) AU2001261767A1 (de)
DE (1) DE60134849D1 (de)
WO (1) WO2001090726A2 (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048734A (en) 1995-09-15 2000-04-11 The Regents Of The University Of Michigan Thermal microvalves in a fluid flow method
US6838680B2 (en) * 1999-05-12 2005-01-04 Aclara Biosciences, Inc. Multiplexed fluorescent detection in microfluidic devices
US6692700B2 (en) 2001-02-14 2004-02-17 Handylab, Inc. Heat-reduction methods and systems related to microfluidic devices
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
US7010391B2 (en) 2001-03-28 2006-03-07 Handylab, Inc. Methods and systems for control of microfluidic devices
US6852287B2 (en) 2001-09-12 2005-02-08 Handylab, Inc. Microfluidic devices having a reduced number of input and output connections
US7323140B2 (en) 2001-03-28 2008-01-29 Handylab, Inc. Moving microdroplets in a microfluidic device
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
US7023007B2 (en) * 2001-07-17 2006-04-04 Caliper Life Sciences, Inc. Methods and systems for alignment of detection optics
DE10200541A1 (de) * 2002-01-09 2003-07-24 Zeiss Carl Jena Gmbh Mikrotiterplatte
US7164533B2 (en) 2003-01-22 2007-01-16 Cyvera Corporation Hybrid random bead/chip based microarray
US7441703B2 (en) * 2002-08-20 2008-10-28 Illumina, Inc. Optical reader for diffraction grating-based encoded optical identification elements
US7901630B2 (en) * 2002-08-20 2011-03-08 Illumina, Inc. Diffraction grating-based encoded microparticle assay stick
CA2496296A1 (en) * 2002-08-20 2004-03-04 Cyvera Corporation Diffraction grating-based encoded micro-particles for multiplexed experiments
US20050227252A1 (en) * 2002-08-20 2005-10-13 Moon John A Diffraction grating-based encoded articles for multiplexed experiments
EP1535241A1 (de) * 2002-08-20 2005-06-01 Cyvera Corporation Auf einem beugungsgitter basierendes optisches identifikationselement
US7923260B2 (en) 2002-08-20 2011-04-12 Illumina, Inc. Method of reading encoded particles
US7190522B2 (en) * 2002-09-12 2007-03-13 Cyvera Corporation Chemical synthesis using diffraction grating-based encoded optical elements
US7872804B2 (en) * 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US7399643B2 (en) * 2002-09-12 2008-07-15 Cyvera Corporation Method and apparatus for aligning microbeads in order to interrogate the same
US7900836B2 (en) * 2002-08-20 2011-03-08 Illumina, Inc. Optical reader system for substrates having an optically readable code
US7508608B2 (en) * 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
US20100255603A9 (en) 2002-09-12 2010-10-07 Putnam Martin A Method and apparatus for aligning microbeads in order to interrogate the same
US7092160B2 (en) * 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
AU2003270726A1 (en) * 2002-09-12 2004-04-30 Cidra Corporation Diffraction grating-based encoded micro-particles for multiplexed experiments
CA2498913A1 (en) * 2002-09-12 2004-03-25 Cyvera Corporation Assay stick comprising coded microbeads
CA2499037A1 (en) * 2002-09-12 2004-03-25 Cyvera Corporation Method and apparatus for labelling using diffraction grating-based encoded optical identification elements
EP2402089A1 (de) 2003-07-31 2012-01-04 Handylab, Inc. Verarbeitung partikelhaltiger Proben
US20060057729A1 (en) * 2003-09-12 2006-03-16 Illumina, Inc. Diffraction grating-based encoded element having a substance disposed thereon
US7433123B2 (en) 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
EP2345739B8 (de) * 2004-05-03 2016-12-07 Handylab, Inc. Mikrofluidische Vorrichtung zur Verarbeitung polynukleotidhaltiger Proben
WO2006020363A2 (en) * 2004-07-21 2006-02-23 Illumina, Inc. Method and apparatus for drug product tracking using encoded optical identification elements
EP2194485B1 (de) 2004-11-16 2012-10-17 Illumina, Inc. Verfahren und Vorrichtung zum Auslesen kodierter Mikroperlen
US7604173B2 (en) * 2004-11-16 2009-10-20 Illumina, Inc. Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same
US7629173B2 (en) * 2004-12-29 2009-12-08 Corning Incorporated Optical reader system and method for monitoring and correcting lateral and angular misalignments of label independent biosensors
WO2006115863A2 (en) * 2005-04-12 2006-11-02 Caliper Life Sciences, Inc. Compact optical detection system for microfluidic devices
US8206974B2 (en) 2005-05-19 2012-06-26 Netbio, Inc. Ruggedized apparatus for analysis of nucleic acid and proteins
JP2009511059A (ja) * 2005-10-11 2009-03-19 ハンディーラブ インコーポレイテッド ポリヌクレオチドサンプル調製装置
EP1783452A1 (de) * 2005-11-02 2007-05-09 Agilent Technologies, Inc. Positionsdetektion anhand bidirektionaler Korrelation
US7623624B2 (en) * 2005-11-22 2009-11-24 Illumina, Inc. Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction
JP2007173083A (ja) * 2005-12-22 2007-07-05 Canon Inc 発光装置
EP2001990B1 (de) 2006-03-24 2016-06-29 Handylab, Inc. Integriertes system zur verarbeitung von mikrofluidischen proben und verwendungsverfahren
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US7998708B2 (en) * 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US7830575B2 (en) * 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
EP2091647A2 (de) * 2006-11-14 2009-08-26 Handylab, Inc. Mikrofluidisches system für parallele amplifikation und erkennung von polynukleotiden
WO2008060604A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US20090136385A1 (en) 2007-07-13 2009-05-28 Handylab, Inc. Reagent Tube
USD621060S1 (en) 2008-07-14 2010-08-03 Handylab, Inc. Microfluidic cartridge
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
EP3741869A1 (de) 2007-07-13 2020-11-25 Handylab, Inc. Materialien zur erfassung von polynukleotiden und verfahren zur verwendung davon
US7869044B2 (en) * 2008-01-16 2011-01-11 Optotrace Technologies, Inc. Optical sensing system based on a micro-array structure
USD618820S1 (en) 2008-07-11 2010-06-29 Handylab, Inc. Reagent holder
USD787087S1 (en) 2008-07-14 2017-05-16 Handylab, Inc. Housing
US20100032582A1 (en) * 2008-08-07 2010-02-11 General Electric Company Fluorescence detection system and method
JP5208774B2 (ja) * 2009-01-08 2013-06-12 株式会社マルコム 蛍光分光光度計
ES2769028T3 (es) 2011-04-15 2020-06-24 Becton Dickinson Co Termociclador microfluídico de barrido en tiempo real
KR101982627B1 (ko) 2011-05-12 2019-05-27 에이엔디이 코포레이션 Ｓｔｒ 유전자좌의 신속한 다중 증폭 방법 및 조성법
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
CA2849917C (en) 2011-09-30 2020-03-31 Becton, Dickinson And Company Unitized reagent strip
EP2773892B1 (de) 2011-11-04 2020-10-07 Handylab, Inc. Vorrichtung zur vorbereitung von polynukleotidproben
RU2658773C2 (ru) 2012-02-03 2018-06-22 Бектон, Дикинсон Энд Компани Система и способ выполнения автоматизированных тестов над множеством биологических проб
CN115389599A (zh) * 2014-03-07 2022-11-25 生命技术公司 用于毛细管电泳的光学系统
JP6533603B2 (ja) * 2018-02-28 2019-06-19 株式会社日立製作所 レーザビーム照射方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2840819A1 (de) * 1978-09-20 1980-04-03 Philips Patentverwaltung Verfahren zum ermitteln des innenmasses von langgestreckten hohlkoerpern, insbesondere von rohren
GB9117974D0 (en) * 1991-08-20 1991-10-09 Renishaw Metrology Ltd Non-contact trigger probe
US5208466A (en) * 1991-10-08 1993-05-04 Beckman Instruments, Inc. Apparatus and method for aligning capillary column and detection optics
JP3736007B2 (ja) * 1997-03-03 2006-01-18 株式会社島津製作所 マイクロチップ電気泳動装置
US5900130A (en) * 1997-06-18 1999-05-04 Alcara Biosciences, Inc. Method for sample injection in microchannel device
US6159749A (en) * 1998-07-21 2000-12-12 Beckman Coulter, Inc. Highly sensitive bead-based multi-analyte assay system using optical tweezers

Also Published As

Publication number Publication date
WO2001090726A3 (en) 2002-03-28
EP1285255A2 (de) 2003-02-26
AU2001261767A1 (en) 2001-12-03
US6515753B2 (en) 2003-02-04
US20020015147A1 (en) 2002-02-07
WO2001090726A2 (en) 2001-11-29
EP1285255B1 (de) 2008-07-16
JP2003534545A (ja) 2003-11-18

Similar Documents

Publication Publication Date Title
DE60134849D1 (de) Ausrichtung eines optischen detektionssystems mit einem kapillarkanal in einem mikrofluiden laborchip
DE60137447D1 (de) Einrichtung zur messung physikalischer grössen mit einem optischen sensor
DK1266608T3 (da) Biologisk væskeprövetagnings- og analytmåleindretning
ATE467113T1 (de) Durchflusszytometerprobenbehandlungsverfahren
EP2040056A3 (de) Optisches Blasenerkennungssystem
DE59914390D1 (de) Vorrichtung zur optischen Distanzmessung
DE60218962D1 (de) Vorrichtung zum farblichen Sortieren von Granulat mit einer aus einem CCD-Linearsensor bestehenden optischen Erkennungsvorrichtung
IL149395A (en) Optical component based temperature measurement in analyte detection devices
NO20011194D0 (no) Dokumentsemantikkanalyse/-valg med kunnskapskreativitetsmulighet
DE50205077D1 (de) Vorrichtung zur Lagerung eines optischen Elementes in einer Optik
EP1736783A4 (de) Fluidmesssystem und optisches system mit langem brennpunkt
DE60236937D1 (de) Mikromuskel in einem biologischen medium
DE69221423T2 (de) Verbesserte Fluoreszenz-Erfassung von Proben in einem Kapillarrohr
FR2855875B1 (fr) Detection de l'ecoulement pour la determination de resultats de tests
DE60309000D1 (de) Automatische präzisionspipettiervorrichtung
DE60213890D1 (de) Reaktiver Sondenchip und Fluoreszenz-Detektionssystem
DE50213114D1 (de) Sensor zur detektion von teilchen in einem gasstrom
HK1069876A1 (en) Non-instrusive device and conduit-mounted light-transmitting device for optical analysis
AU2003290784A8 (en) Methods for detecting asymmetric dimethylarginine in a biological sample
ATE439586T1 (de) Volumenzähler-prüfvorrichtung
GB2402218B (en) Microtome with an orientable sample holder having a zero-point indication
DE60137748D1 (de) Analysesystem zur Feststellung der Stickstoffkonzentration mit hoher Genauigkeit
DE602004007231D1 (de) Optische Vorrichtung zur Erfassung eines optischen Signales und deren Herstellungsverfahren
DE69817793D1 (de) Detektion von hydrophoben analyten mit niedrigem gehalt in umweltproben
FR2862069B1 (fr) Analyse automatique d'echantillons cellulaires

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: MONOGRAM BIOSCIENCES, INC., MOUNTAIN VIEW, CAL, US

8364 No opposition during term of opposition