DE60132815D1 - Röntgenkristallstruktur mit 5.5 a auflösung von funktionalen komplexen des bakteriellen ribosoms, beinhaltend transfer-rna und modell boten-rna - Google Patents
Röntgenkristallstruktur mit 5.5 a auflösung von funktionalen komplexen des bakteriellen ribosoms, beinhaltend transfer-rna und modell boten-rnaInfo
- Publication number
- DE60132815D1 DE60132815D1 DE60132815T DE60132815T DE60132815D1 DE 60132815 D1 DE60132815 D1 DE 60132815D1 DE 60132815 T DE60132815 T DE 60132815T DE 60132815 T DE60132815 T DE 60132815T DE 60132815 D1 DE60132815 D1 DE 60132815D1
- Authority
- DE
- Germany
- Prior art keywords
- rna
- resolution
- messenge
- model
- crystal structure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25460300P | 2000-12-09 | 2000-12-09 | |
US27801301P | 2001-03-22 | 2001-03-22 | |
US29439401P | 2001-05-30 | 2001-05-30 | |
PCT/US2001/047975 WO2002046392A2 (en) | 2000-12-09 | 2001-12-10 | X ray crystal structures at 5.5 a resolution of functional complexes of the bacterial ribosome containing transfer rna and model messenger rnas |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60132815D1 true DE60132815D1 (de) | 2008-03-27 |
Family
ID=27400793
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60132815T Expired - Lifetime DE60132815D1 (de) | 2000-12-09 | 2001-12-10 | Röntgenkristallstruktur mit 5.5 a auflösung von funktionalen komplexen des bakteriellen ribosoms, beinhaltend transfer-rna und modell boten-rna |
Country Status (9)
Country | Link |
---|---|
US (1) | US7133783B2 (de) |
EP (1) | EP1351982B1 (de) |
JP (1) | JP2004532972A (de) |
AT (1) | ATE386051T1 (de) |
AU (1) | AU2002241614A1 (de) |
CA (1) | CA2429895A1 (de) |
DE (1) | DE60132815D1 (de) |
IL (1) | IL156110A0 (de) |
WO (1) | WO2002046392A2 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6947844B2 (en) * | 2000-08-09 | 2005-09-20 | Yale University | Modulators of ribosomal function and identification thereof |
US6638908B1 (en) | 2000-08-09 | 2003-10-28 | Yale University | Crystals of the large ribosomal subunit |
IL151012A0 (en) * | 2001-08-03 | 2003-02-12 | Ribosomes Structure And Protei | Ribosomes structure and protein synthesis inhibitors |
US6952650B2 (en) * | 2001-08-03 | 2005-10-04 | Yale University | Modulators of ribosomal function and identification thereof |
WO2003047543A1 (en) * | 2001-10-05 | 2003-06-12 | Procyte Corporation | Methods for the treatment of hyperpigmentation of skin |
US8374794B1 (en) | 2003-06-02 | 2013-02-12 | Rib-X Pharmaceuticals, Inc. | Protein synthesis modulators |
US8428884B1 (en) | 2003-07-14 | 2013-04-23 | Rib-X Pharmaceuticals, Inc. | Protein synthesis modulators |
US20070118296A1 (en) * | 2003-11-07 | 2007-05-24 | Dna Software Inc. | System and methods for three dimensional molecular structural analysis |
US7960641B2 (en) * | 2008-01-30 | 2011-06-14 | Mario Rabinowitz | Tracking and focusing adjustable fresnel lens array solar concentrator |
WO2012142542A2 (en) * | 2011-04-15 | 2012-10-18 | Cornell University | New ribosomal targets for antibiotic drug discovery |
WO2013041223A1 (en) * | 2011-09-20 | 2013-03-28 | Eth Zurich | Crystal structure of the 60s eukaryotic ribosomal subunit and its uses |
US10556934B2 (en) | 2015-01-29 | 2020-02-11 | Yeda Research And Development Co. Ltd. | Crystal structure of the large ribosomal subunit from S. aureus |
EP3634991A1 (de) | 2017-05-23 | 2020-04-15 | Technion Research & Development Foundation Limited | Mittel zur hemmung von gads-dimerisierung und verfahren zur verwendung davon |
JP2022532796A (ja) * | 2019-05-22 | 2022-07-19 | ザ・ユニバーシティ・オブ・シカゴ | 係留ケトキサール誘導体に関連する組成物および方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT155423B (de) | 1938-04-02 | 1939-01-25 | Victor Potrusil | Heizvorrichtung für Haarwellgeräte. |
US5856122A (en) | 1993-08-24 | 1999-01-05 | University Of Alberta | Modification of pertussis toxin |
ATE272719T1 (de) | 1993-11-26 | 2004-08-15 | Lawrence B Hendry | Der entwurf von medikamenten, die in die rezeptor-ligand-dna wechselwirkungen eingreifen |
US5856116A (en) | 1994-06-17 | 1999-01-05 | Vertex Pharmaceuticals, Incorporated | Crystal structure and mutants of interleukin-1 beta converting enzyme |
MX9705906A (es) | 1995-02-03 | 1997-10-31 | Novo Nordisk As | Un metodo para diseñar mutantes de alfa-amilasa con propiedades predeterminadas. |
US5835382A (en) | 1996-04-26 | 1998-11-10 | The Scripps Research Institute | Small molecule mimetics of erythropoietin |
WO2000069391A2 (en) | 1999-05-13 | 2000-11-23 | The University Of Utah | CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN L11/GTPASE ACTIVATING REGION rRNA AND USES THEREOF |
IL144082A0 (en) | 2000-07-14 | 2002-05-23 | Medical Res Council | Crystal structure of antibiotics bound to the 30s ribosome and its use |
GB0029870D0 (en) | 2000-07-14 | 2001-01-24 | Medical Res Council | Crystal structure (IV) |
US6947844B2 (en) | 2000-08-09 | 2005-09-20 | Yale University | Modulators of ribosomal function and identification thereof |
-
2001
- 2001-12-10 CA CA002429895A patent/CA2429895A1/en not_active Abandoned
- 2001-12-10 AU AU2002241614A patent/AU2002241614A1/en not_active Abandoned
- 2001-12-10 AT AT01988295T patent/ATE386051T1/de not_active IP Right Cessation
- 2001-12-10 WO PCT/US2001/047975 patent/WO2002046392A2/en active IP Right Grant
- 2001-12-10 JP JP2002548110A patent/JP2004532972A/ja not_active Withdrawn
- 2001-12-10 US US10/013,379 patent/US7133783B2/en not_active Expired - Lifetime
- 2001-12-10 IL IL15611001A patent/IL156110A0/xx unknown
- 2001-12-10 DE DE60132815T patent/DE60132815D1/de not_active Expired - Lifetime
- 2001-12-10 EP EP01988295A patent/EP1351982B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2429895A1 (en) | 2002-06-13 |
US20020188108A1 (en) | 2002-12-12 |
EP1351982A2 (de) | 2003-10-15 |
IL156110A0 (en) | 2003-12-23 |
ATE386051T1 (de) | 2008-03-15 |
US7133783B2 (en) | 2006-11-07 |
EP1351982B1 (de) | 2008-02-13 |
AU2002241614A1 (en) | 2002-06-18 |
JP2004532972A (ja) | 2004-10-28 |
WO2002046392A2 (en) | 2002-06-13 |
WO2002046392A3 (en) | 2003-06-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |