DE60126768D1 - ADJUVANTIEN UND VERFAHREN ZUR INDUKTION EINER Th2 IMMUNANTWORT - Google Patents

ADJUVANTIEN UND VERFAHREN ZUR INDUKTION EINER Th2 IMMUNANTWORT

Info

Publication number
DE60126768D1
DE60126768D1 DE60126768T DE60126768T DE60126768D1 DE 60126768 D1 DE60126768 D1 DE 60126768D1 DE 60126768 T DE60126768 T DE 60126768T DE 60126768 T DE60126768 T DE 60126768T DE 60126768 D1 DE60126768 D1 DE 60126768D1
Authority
DE
Germany
Prior art keywords
gingivalis
immune response
detoxified
derivatives
lps
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60126768T
Other languages
English (en)
Other versions
DE60126768T2 (de
Inventor
Bali Pulendran
Jacques F Banchereau
Christopher W Cutler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baylor Research Institute
Original Assignee
Baylor Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor Research Institute filed Critical Baylor Research Institute
Publication of DE60126768D1 publication Critical patent/DE60126768D1/de
Application granted granted Critical
Publication of DE60126768T2 publication Critical patent/DE60126768T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/739—Lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60126768T 2000-06-16 2001-06-18 ADJUVANTIEN UND VERFAHREN ZUR INDUKTION EINER Th2 IMMUNANTWORT Expired - Lifetime DE60126768T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21218200P 2000-06-16 2000-06-16
US212182P 2000-06-16
PCT/US2001/019411 WO2001097838A2 (en) 2000-06-16 2001-06-18 Adjuvants and processes to induce a specific type of immune response

Publications (2)

Publication Number Publication Date
DE60126768D1 true DE60126768D1 (de) 2007-04-05
DE60126768T2 DE60126768T2 (de) 2007-10-25

Family

ID=22789909

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60126768T Expired - Lifetime DE60126768T2 (de) 2000-06-16 2001-06-18 ADJUVANTIEN UND VERFAHREN ZUR INDUKTION EINER Th2 IMMUNANTWORT

Country Status (6)

Country Link
US (1) US6818221B2 (de)
EP (1) EP1292332B1 (de)
AT (1) ATE354371T1 (de)
AU (1) AU2001266983A1 (de)
DE (1) DE60126768T2 (de)
WO (1) WO2001097838A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040259790A1 (en) * 2003-01-30 2004-12-23 Bali Pulendran Methods for identifying and administering agents that bias the immune response via dendritic cells
US20050048072A1 (en) * 2003-08-25 2005-03-03 3M Innovative Properties Company Immunostimulatory combinations and treatments
US7622128B2 (en) * 2005-12-13 2009-11-24 University Of Washington Porphyromonas gingivalis 1435/1449 LPS as an immune modulator

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997034629A1 (en) * 1996-03-22 1997-09-25 University Of Georgia Research Foundation, Inc. Immunogenic compositions comprising porphyromonas gingivalis peptides and methods
AUPN901296A0 (en) * 1996-03-29 1996-04-26 University Of Melbourne, The Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis

Also Published As

Publication number Publication date
US20040082538A1 (en) 2004-04-29
EP1292332A2 (de) 2003-03-19
US6818221B2 (en) 2004-11-16
AU2001266983A1 (en) 2002-01-02
WO2001097838A3 (en) 2002-06-27
EP1292332B1 (de) 2007-02-21
ATE354371T1 (de) 2007-03-15
DE60126768T2 (de) 2007-10-25
WO2001097838A2 (en) 2001-12-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition