ATE354371T1 - Adjuvantien und verfahren zur induktion einer th2 immunantwort - Google Patents

Adjuvantien und verfahren zur induktion einer th2 immunantwort

Info

Publication number
ATE354371T1
ATE354371T1 AT01944590T AT01944590T ATE354371T1 AT E354371 T1 ATE354371 T1 AT E354371T1 AT 01944590 T AT01944590 T AT 01944590T AT 01944590 T AT01944590 T AT 01944590T AT E354371 T1 ATE354371 T1 AT E354371T1
Authority
AT
Austria
Prior art keywords
immune response
gingivalis
detoxified
derivatives
lps
Prior art date
Application number
AT01944590T
Other languages
English (en)
Inventor
Bali Pulendran
Jacques F Banchereau
Christopher W Cutler
Original Assignee
Baylor Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor Res Inst filed Critical Baylor Res Inst
Application granted granted Critical
Publication of ATE354371T1 publication Critical patent/ATE354371T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/739—Lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT01944590T 2000-06-16 2001-06-18 Adjuvantien und verfahren zur induktion einer th2 immunantwort ATE354371T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21218200P 2000-06-16 2000-06-16

Publications (1)

Publication Number Publication Date
ATE354371T1 true ATE354371T1 (de) 2007-03-15

Family

ID=22789909

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01944590T ATE354371T1 (de) 2000-06-16 2001-06-18 Adjuvantien und verfahren zur induktion einer th2 immunantwort

Country Status (6)

Country Link
US (1) US6818221B2 (de)
EP (1) EP1292332B1 (de)
AT (1) ATE354371T1 (de)
AU (1) AU2001266983A1 (de)
DE (1) DE60126768T2 (de)
WO (1) WO2001097838A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040259790A1 (en) * 2003-01-30 2004-12-23 Bali Pulendran Methods for identifying and administering agents that bias the immune response via dendritic cells
EP1660122A4 (de) * 2003-08-25 2007-10-24 3M Innovative Properties Co Immunstimulatorische kombinationen und behandlungen
US7622128B2 (en) * 2005-12-13 2009-11-24 University Of Washington Porphyromonas gingivalis 1435/1449 LPS as an immune modulator

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997034629A1 (en) * 1996-03-22 1997-09-25 University Of Georgia Research Foundation, Inc. Immunogenic compositions comprising porphyromonas gingivalis peptides and methods
AUPN901296A0 (en) * 1996-03-29 1996-04-26 University Of Melbourne, The Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis

Also Published As

Publication number Publication date
AU2001266983A1 (en) 2002-01-02
US6818221B2 (en) 2004-11-16
EP1292332A2 (de) 2003-03-19
WO2001097838A3 (en) 2002-06-27
DE60126768D1 (de) 2007-04-05
WO2001097838A2 (en) 2001-12-27
US20040082538A1 (en) 2004-04-29
DE60126768T2 (de) 2007-10-25
EP1292332B1 (de) 2007-02-21

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties