DE60126307D1 - Marker-unterstützte auswahl von rindvieh für verbesserte milchproduktion unter verwendung des diacylglycerin-acyltransferase-gens dga5 - Google Patents

Marker-unterstützte auswahl von rindvieh für verbesserte milchproduktion unter verwendung des diacylglycerin-acyltransferase-gens dga5

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Publication number
DE60126307D1
DE60126307D1 DE60126307T DE60126307T DE60126307D1 DE 60126307 D1 DE60126307 D1 DE 60126307D1 DE 60126307 T DE60126307 T DE 60126307T DE 60126307 T DE60126307 T DE 60126307T DE 60126307 D1 DE60126307 D1 DE 60126307D1
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Germany
Prior art keywords
dga5
controls
marker assisted
acyltransferase gene
assisted self
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Expired - Lifetime
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DE60126307T
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English (en)
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DE60126307T2 (de
Inventor
Michel Alphonse Julien Georges
Wouter Herman Rober Coppieters
Bernard Marie-Josee Je Grisart
Russell Grant Snell
Suzanne Jean Reid
Christine Ann Ford
Richard John Spelman
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Priority claimed from NZ50788800A external-priority patent/NZ507888A/xx
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE60126307D1 publication Critical patent/DE60126307D1/de
Publication of DE60126307T2 publication Critical patent/DE60126307T2/de
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Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/101Bovine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/02Animal zootechnically ameliorated
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C2230/00Aspects relating to animal feed or genotype
    • A23C2230/05Milk or milk products from transgenic animals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/20Pseudochromosomes, minichrosomosomes
    • C12N2800/204Pseudochromosomes, minichrosomosomes of bacterial origin, e.g. BAC
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/124Animal traits, i.e. production traits, including athletic performance or the like
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE60126307T 2000-10-31 2001-10-31 Marker-unterstützte auswahl von rindvieh für verbesserte milchproduktion unter verwendung des diacylglycerin-acyltransferase-gens dgat1 Expired - Lifetime DE60126307T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
NZ50788800 2000-10-31
NZ50788800A NZ507888A (en) 2000-10-31 2000-10-31 Mutations in bovine milk diglycerol-o-acyltransferase (DAGT1) affecting a quantitative trait locus (QLT) resulting in altered milk characteristics such as increased protein and decreased fat content
NZ50866200 2000-12-06
NZ50866200 2000-12-06
PCT/NZ2001/000245 WO2002036824A1 (en) 2000-10-31 2001-10-31 Marker assisted selection of bovine for improved milk production using diacylglycerol acyltransferase gene dgat1

Publications (2)

Publication Number Publication Date
DE60126307D1 true DE60126307D1 (de) 2007-03-15
DE60126307T2 DE60126307T2 (de) 2007-12-27

Family

ID=26652224

Family Applications (2)

Application Number Title Priority Date Filing Date
DE01992795T Pending DE01992795T1 (de) 2000-10-31 2001-10-31 Marker-unterstützte auswahl von rindvieh für verbesserte milchproduktion unter verwendung des diacylglycerin-acyltransferase-gens dgat1
DE60126307T Expired - Lifetime DE60126307T2 (de) 2000-10-31 2001-10-31 Marker-unterstützte auswahl von rindvieh für verbesserte milchproduktion unter verwendung des diacylglycerin-acyltransferase-gens dgat1

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE01992795T Pending DE01992795T1 (de) 2000-10-31 2001-10-31 Marker-unterstützte auswahl von rindvieh für verbesserte milchproduktion unter verwendung des diacylglycerin-acyltransferase-gens dgat1

Country Status (7)

Country Link
US (1) US7537888B2 (de)
EP (1) EP1330552B1 (de)
AT (1) ATE352627T1 (de)
AU (2) AU2422902A (de)
CA (1) CA2427223C (de)
DE (2) DE01992795T1 (de)
WO (1) WO2002036824A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6444427B1 (en) * 2000-07-11 2002-09-03 The Regents Of The University Of California Polymorphisms in a diacylglycerol acyltransferase gene, and methods of use thereof
CA2453001C (en) * 2001-07-06 2011-05-24 Arbeitsgemeinschaft Deutscher Rinderzuchter E.V. Method of testing a mammal for its predisposition for fat content of milk and/or its predisposition for meat marbling
EP2329722A1 (de) * 2001-07-16 2011-06-08 Therapeutic Foods Limited Milchkuhpopulationen, die Milch mit den gewünschten Eigenschaften produzieren, sowie Herstellungs- und Verwendungsverfahren davon
US20050260603A1 (en) 2002-12-31 2005-11-24 Mmi Genomics, Inc. Compositions for inferring bovine traits
US20040185559A1 (en) 2003-03-21 2004-09-23 Isis Pharmaceuticals Inc. Modulation of diacylglycerol acyltransferase 1 expression
EP1633889B1 (de) 2003-05-30 2010-09-01 The Board Of Trustees Of The University Of Illinois Genexpressionsprofile zur identifizierung von genetisch bevorzugten huftieren
BRPI0415468A (pt) * 2003-10-24 2007-03-27 Mmi Genomics Inc métodos e sistemas para inferir caracterìsticas para controlar criação não de gado
US20060172329A1 (en) * 2005-01-13 2006-08-03 The University Of Missouri System DNA markers for cattle growth
US20060166244A1 (en) * 2005-01-14 2006-07-27 The University Of Missouri System DNA markers for increased milk production in cattle
EP2069530A2 (de) * 2006-02-06 2009-06-17 Aarhus Universitet Qtls für eutergesundheitsmerkmale bei rindern
EP1996722A4 (de) * 2006-03-30 2009-09-09 Innovative Dairy Products Pty Chromosomale blöcke als marker für eigenschaften
WO2008039257A2 (en) * 2006-06-13 2008-04-03 Monsanto Technology Llc Single nucleotide polymorphisms and use of same in selection of dairy cattle
EP2057177B1 (de) 2006-08-04 2012-11-21 Isis Pharmaceuticals, Inc. Zusammensetzungen und ihre verwendung in bezug auf diacylglycerol-acyltransferase 1
WO2008140467A2 (en) * 2006-09-29 2008-11-20 Pfizer Inc. Genetic markers and methods for improving dairy productivity and fitness traits
CA2673174C (en) 2006-12-21 2016-11-08 Agriculture Victoria Services Pty Limited Artificial selection method and reagents
EP2121976A2 (de) * 2007-02-15 2009-11-25 Wageningen Universiteit Verfahren zur auswahl eines milch mit verbesserter fettsäurezusammensetzung produzierenden nichtmenschlichen säugers
AU2008276488A1 (en) * 2007-07-16 2009-01-22 Pfizer Inc. Methods of improving a genomic marker index of dairy animals and products
JP2010538643A (ja) * 2007-09-12 2010-12-16 ファイザー・インコーポレイテッド 遺伝マーカー及び関連するエピスタシス交互作用の使用方法
NZ561999A (en) * 2007-09-26 2010-05-28 Vialactia Biosciences Nz Ltd Marker assisted selection of bovine for milk fat colour
CN101952718A (zh) * 2007-12-17 2011-01-19 美国辉瑞有限公司 改善产乳动物和产品的遗传图谱的方法
BRPI0923636A2 (pt) * 2008-12-24 2016-07-26 Fonterra Co Operative Group seleção de animais para ocmposição desejada de leite e/ou tecido
US20130115596A1 (en) * 2010-03-25 2013-05-09 Genoa Biotecnologia S.A. Dna polymorphisms as molecular markers in cattle
AU2019240760A1 (en) * 2018-03-28 2020-10-15 Agriculture Victoria Services Pty Ltd Milk phospholipids

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3225997A (en) * 1996-05-30 1998-01-05 Trustees Of Columbia University In The City Of New York, The Dna encoding acylcoenzyme a: cholesterol acyltransferase and uses thereof
DK1071710T4 (da) * 1998-04-15 2011-12-12 Merck Serono Biodevelopment Genomisk sekvens for 5-lipoxygenase-aktiveringsproteinet (FLAP), polymorfe markører deri og fremgangsmåder til påvisning af astma
US6344548B1 (en) * 1998-06-24 2002-02-05 The Regents Of The University Of California Diacylglycerol o-acyltransferase

Also Published As

Publication number Publication date
EP1330552A4 (de) 2005-06-22
WO2002036824A1 (en) 2002-05-10
EP1330552B1 (de) 2007-01-24
EP1330552A1 (de) 2003-07-30
AU2002224229B2 (en) 2007-11-29
AU2422902A (en) 2002-05-15
US7537888B2 (en) 2009-05-26
DE60126307T2 (de) 2007-12-27
ATE352627T1 (de) 2007-02-15
CA2427223C (en) 2013-05-14
DE01992795T1 (de) 2004-12-16
CA2427223A1 (en) 2002-05-10
US20040076977A1 (en) 2004-04-22

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