DE60124523D1 - Zusammensetzung einer Parvovirus VP1-Proteinvariante und eines arvovirus NS1-Proteins zur Induktion von Zytolyse - Google Patents
Zusammensetzung einer Parvovirus VP1-Proteinvariante und eines arvovirus NS1-Proteins zur Induktion von ZytolyseInfo
- Publication number
- DE60124523D1 DE60124523D1 DE60124523T DE60124523T DE60124523D1 DE 60124523 D1 DE60124523 D1 DE 60124523D1 DE 60124523 T DE60124523 T DE 60124523T DE 60124523 T DE60124523 T DE 60124523T DE 60124523 D1 DE60124523 D1 DE 60124523D1
- Authority
- DE
- Germany
- Prior art keywords
- protein
- parvovirus
- composition
- arvovirus
- induce cytolysis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 101710132601 Capsid protein Proteins 0.000 title abstract 2
- 101710197658 Capsid protein VP1 Proteins 0.000 title abstract 2
- 241000125945 Protoparvovirus Species 0.000 title abstract 2
- 101710118046 RNA-directed RNA polymerase Proteins 0.000 title abstract 2
- 101710108545 Viral protein 1 Proteins 0.000 title abstract 2
- 206010057248 Cell death Diseases 0.000 title 1
- 101710128560 Initiator protein NS1 Proteins 0.000 title 1
- 101710144127 Non-structural protein 1 Proteins 0.000 title 1
- 230000009089 cytolysis Effects 0.000 title 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 108700038653 parvovirus NS1 Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
- 230000001173 tumoral effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14311—Parvovirus, e.g. minute virus of mice
- C12N2750/14322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01116856A EP1275658B1 (de) | 2001-07-10 | 2001-07-10 | Zusammensetzung einer Parvovirus VP1-Proteinvariante und eines arvovirus NS1-Proteins zur Induktion von Zytolyse |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60124523D1 true DE60124523D1 (de) | 2006-12-28 |
| DE60124523T2 DE60124523T2 (de) | 2007-09-06 |
Family
ID=8178011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60124523T Expired - Lifetime DE60124523T2 (de) | 2001-07-10 | 2001-07-10 | Zusammensetzung einer Parvovirus VP1-Proteinvariante und eines arvovirus NS1-Proteins zur Induktion von Zytolyse |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20040208886A1 (de) |
| EP (1) | EP1275658B1 (de) |
| AT (1) | ATE345352T1 (de) |
| AU (1) | AU2002336926A1 (de) |
| DE (1) | DE60124523T2 (de) |
| WO (1) | WO2003006067A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE345352T1 (de) * | 2001-07-10 | 2006-12-15 | Deutsches Krebsforsch | Zusammensetzung einer parvovirus vp1- proteinvariante und eines arvovirus ns1-proteins zur induktion von zytolyse |
| EP1473306A1 (de) | 2003-04-30 | 2004-11-03 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Als cytotoxin geeignetes fusionspolypeptid |
| ES2556710T3 (es) * | 2004-09-24 | 2016-01-19 | Novartis Ag | Proteínas capsidiales VP1 modificadas del parvovirus B19 |
| EP2404609A1 (de) | 2010-07-07 | 2012-01-11 | Deutsches Krebsforschungszentrum | Verwendung vom Parvovirus zur Beseitigung von Krebsstammzellen |
| US9555098B2 (en) * | 2012-09-10 | 2017-01-31 | Merial Inc. | Attenuated parvovirus vaccine for Muscovy duck parvovirus and goose parvovirus (Derzsys disease) |
| EP3738972A1 (de) | 2019-05-13 | 2020-11-18 | Deutsches Krebsforschungszentrum | Parvolysin |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2282998T3 (es) | 1996-01-02 | 2007-10-16 | Institut Pasteur | Pseudo-particularmente viricas recombinadas y aplicaciomnes vacunales y antitumorales. |
| SE520177C2 (sv) * | 1998-11-24 | 2003-06-03 | Kristina Broliden | Användning av tomma, icke-infektiösa, rekombinanta parvoviruskapsidpartiklar, eller P-antigenblockerande delar därav, för framställning av läkemedel för ihibering av hematopoietiska stamceller |
| ATE345352T1 (de) | 2001-07-10 | 2006-12-15 | Deutsches Krebsforsch | Zusammensetzung einer parvovirus vp1- proteinvariante und eines arvovirus ns1-proteins zur induktion von zytolyse |
-
2001
- 2001-07-10 AT AT01116856T patent/ATE345352T1/de not_active IP Right Cessation
- 2001-07-10 EP EP01116856A patent/EP1275658B1/de not_active Expired - Lifetime
- 2001-07-10 DE DE60124523T patent/DE60124523T2/de not_active Expired - Lifetime
-
2002
- 2002-07-10 US US10/483,234 patent/US20040208886A1/en not_active Abandoned
- 2002-07-10 WO PCT/EP2002/007706 patent/WO2003006067A2/en not_active Application Discontinuation
- 2002-07-10 AU AU2002336926A patent/AU2002336926A1/en not_active Abandoned
-
2009
- 2009-09-30 US US12/570,913 patent/US8450289B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20040208886A1 (en) | 2004-10-21 |
| AU2002336926A1 (en) | 2003-01-29 |
| WO2003006067A2 (en) | 2003-01-23 |
| EP1275658A1 (de) | 2003-01-15 |
| DE60124523T2 (de) | 2007-09-06 |
| WO2003006067A3 (en) | 2003-05-08 |
| EP1275658B1 (de) | 2006-11-15 |
| US8450289B2 (en) | 2013-05-28 |
| US20100029751A1 (en) | 2010-02-04 |
| ATE345352T1 (de) | 2006-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |