DE60116794D1 - Schallausstoss von fluiden aus mehreren behältern - Google Patents

Schallausstoss von fluiden aus mehreren behältern

Info

Publication number
DE60116794D1
DE60116794D1 DE60116794T DE60116794T DE60116794D1 DE 60116794 D1 DE60116794 D1 DE 60116794D1 DE 60116794 T DE60116794 T DE 60116794T DE 60116794 T DE60116794 T DE 60116794T DE 60116794 D1 DE60116794 D1 DE 60116794D1
Authority
DE
Germany
Prior art keywords
fluids
sound outlet
multiple containers
fluid
arrays
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60116794T
Other languages
English (en)
Other versions
DE60116794T2 (de
Inventor
N Ellson
K Foote
W Mutz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Picoliter Inc
Original Assignee
Picoliter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/727,392 external-priority patent/US20020061258A1/en
Application filed by Picoliter Inc filed Critical Picoliter Inc
Application granted granted Critical
Publication of DE60116794D1 publication Critical patent/DE60116794D1/de
Publication of DE60116794T2 publication Critical patent/DE60116794T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • B41J2/135—Nozzles
    • B41J2/14—Structure thereof only for on-demand ink jet heads
    • B41J2/14008—Structure of acoustic ink jet print heads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00378—Piezoelectric or ink jet dispensers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/0059—Sequential processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00608—DNA chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/0061—The surface being organic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00623—Immobilisation or binding
    • B01J2219/00626—Covalent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
    • B01J2219/00641—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium the porous medium being continuous, e.g. porous oxide substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • B05B17/0615—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced at the free surface of the liquid or other fluent material in a container and subjected to the vibrations
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Particle Formation And Scattering Control In Inkjet Printers (AREA)
  • Quick-Acting Or Multi-Walled Pipe Joints (AREA)
DE60116794T 2000-09-25 2001-09-25 Schallausstoss von fluiden aus mehreren behältern Expired - Lifetime DE60116794T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US66999600A 2000-09-25 2000-09-25
US66999700A 2000-09-25 2000-09-25
US669997 2000-09-25
US669996 2000-09-25
US727392 2000-11-29
US09/727,392 US20020061258A1 (en) 2000-09-25 2000-11-29 Focused acoustic energy in the preparation and screening of combinatorial libraries
PCT/US2001/030113 WO2002024325A2 (en) 2000-09-25 2001-09-25 Acoustic ejection of fluids from a plurality of reservoirs

Publications (2)

Publication Number Publication Date
DE60116794D1 true DE60116794D1 (de) 2006-04-06
DE60116794T2 DE60116794T2 (de) 2006-08-31

Family

ID=27418197

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60116794T Expired - Lifetime DE60116794T2 (de) 2000-09-25 2001-09-25 Schallausstoss von fluiden aus mehreren behältern

Country Status (7)

Country Link
EP (2) EP2263791B1 (de)
JP (1) JP4624644B2 (de)
AT (1) ATE315957T1 (de)
AU (2) AU2433602A (de)
CA (1) CA2423068C (de)
DE (1) DE60116794T2 (de)
WO (1) WO2002024325A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001293086B2 (en) * 2000-09-25 2006-04-13 Picoliter Inc. Focused acoustic energy method and device for generating droplets of immiscible fluids
US20020061258A1 (en) * 2000-09-25 2002-05-23 Mutz Mitchell W. Focused acoustic energy in the preparation and screening of combinatorial libraries
US6642061B2 (en) * 2000-09-25 2003-11-04 Picoliter Inc. Use of immiscible fluids in droplet ejection through application of focused acoustic energy
US6596239B2 (en) 2000-12-12 2003-07-22 Edc Biosystems, Inc. Acoustically mediated fluid transfer methods and uses thereof
US6610223B2 (en) 2001-03-30 2003-08-26 Picoliter Inc. Focused acoustic energy in the generation of solid particles
US6416164B1 (en) * 2001-07-20 2002-07-09 Picoliter Inc. Acoustic ejection of fluids using large F-number focusing elements
US6976639B2 (en) * 2001-10-29 2005-12-20 Edc Biosystems, Inc. Apparatus and method for droplet steering
US6932097B2 (en) 2002-06-18 2005-08-23 Picoliter Inc. Acoustic control of the composition and/or volume of fluid in a reservoir
JP4559218B2 (ja) * 2002-06-18 2010-10-06 ピコリター インコーポレイテッド リザーバー中の流体内容物の音響評価および／または制御
US6893115B2 (en) 2002-09-20 2005-05-17 Picoliter Inc. Frequency correction for drop size control
GB0303861D0 (en) * 2003-02-20 2003-03-26 Arrayjet Ltd Improved printing method and apparatus
US20060183261A1 (en) * 2005-02-15 2006-08-17 Dudenhoefer Christie L Method of forming a biological sensor
US10016757B2 (en) * 2011-04-28 2018-07-10 Labcyte Inc. Sample containers adapted for acoustic ejections and sample preservation and methods thereof
WO2016013115A1 (ja) 2014-07-25 2016-01-28 株式会社 リージャー 希釈生体試料成分の分析方法
GB201905181D0 (en) * 2019-04-11 2019-05-29 Arrayjet Ltd Method and apparatus for substrate handling and printing

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4308547A (en) 1978-04-13 1981-12-29 Recognition Equipment Incorporated Liquid drop emitter
US4500707A (en) 1980-02-29 1985-02-19 University Patents, Inc. Nucleosides useful in the preparation of polynucleotides
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US5367066A (en) 1984-10-16 1994-11-22 Chiron Corporation Oligonucleotides with selectably cleavable and/or abasic sites
US5118605A (en) 1984-10-16 1992-06-02 Chiron Corporation Polynucleotide determination with selectable cleavage sites
US4775619A (en) 1984-10-16 1988-10-04 Chiron Corporation Polynucleotide determination with selectable cleavage sites
US5258506A (en) 1984-10-16 1993-11-02 Chiron Corporation Photolabile reagents for incorporation into oligonucleotide chains
US4877745A (en) * 1986-11-17 1989-10-31 Abbott Laboratories Apparatus and process for reagent fluid dispensing and printing
US4797693A (en) 1987-06-02 1989-01-10 Xerox Corporation Polychromatic acoustic ink printing
US6054270A (en) 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
US5700637A (en) 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
GB8822228D0 (en) 1988-09-21 1988-10-26 Southern E M Support-bound oligonucleotides
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5041849A (en) 1989-12-26 1991-08-20 Xerox Corporation Multi-discrete-phase Fresnel acoustic lenses and their application to acoustic ink printing
US5087931A (en) 1990-05-15 1992-02-11 Xerox Corporation Pressure-equalized ink transport system for acoustic ink printers
JPH06504997A (ja) 1990-12-06 1994-06-09 アフィメトリックス，　インコーポレイテッド 非常に大きい規模の固定化されたポリマーの合成
US5629724A (en) * 1992-05-29 1997-05-13 Xerox Corporation Stabilization of the free surface of a liquid
US6015880A (en) 1994-03-16 2000-01-18 California Institute Of Technology Method and substrate for performing multiple sequential reactions on a matrix
US5669971A (en) * 1994-04-06 1997-09-23 Specialty Coating Systems, Inc. Selective coating apparatus
US5565113A (en) * 1994-05-18 1996-10-15 Xerox Corporation Lithographically defined ejection units
US5807522A (en) * 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US5520715A (en) 1994-07-11 1996-05-28 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Directional electrostatic accretion process employing acoustic droplet formation
US5580731A (en) 1994-08-25 1996-12-03 Chiron Corporation N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith
US5985356A (en) * 1994-10-18 1999-11-16 The Regents Of The University Of California Combinatorial synthesis of novel materials
JPH08254446A (ja) 1995-03-16 1996-10-01 Fujitsu Ltd 超音波印字方法，超音波印字装置及び音響レンズの成形方法
JP3296213B2 (ja) * 1996-10-30 2002-06-24 三菱電機株式会社 液体エジェクタおよび液体エジェクタを用いる印刷装置
US5965719A (en) 1996-11-15 1999-10-12 Sunsorb Biotech, Inc. Combinatorial synthesis of carbohydrate libraries
US5780603A (en) 1996-11-15 1998-07-14 Synsorb Biotech, Inc. Combinatorial synthesis of carbohydrate libraries
US5877580A (en) * 1996-12-23 1999-03-02 Regents Of The University Of California Micromachined chemical jet dispenser
US5756712A (en) 1997-01-23 1998-05-26 E. I. Du Pont De Nemours And Company Peptidodisaccharides as oligosaccharide mimetics
US6007183A (en) 1997-11-25 1999-12-28 Xerox Corporation Acoustic metal jet fabrication using an inert gas
DE29823691U1 (de) * 1998-04-16 1999-09-23 EVOTEC BioSystems AG, 22525 Hamburg Vorrichtung zum Erzeugen und Ausstoßen kleiner Fluidtropfen mit einer als reflektivem akustischen Element ausgebildeten Druckkammer
US6048699A (en) * 1998-10-19 2000-04-11 Motorola, Inc. Method of fabricating bio-chip arrays
US6296673B1 (en) * 1999-06-18 2001-10-02 The Regents Of The University Of California Methods and apparatus for performing array microcrystallizations
AU2001293086B2 (en) * 2000-09-25 2006-04-13 Picoliter Inc. Focused acoustic energy method and device for generating droplets of immiscible fluids
US6596239B2 (en) * 2000-12-12 2003-07-22 Edc Biosystems, Inc. Acoustically mediated fluid transfer methods and uses thereof

Also Published As

Publication number Publication date
CA2423068C (en) 2011-01-25
AU2433602A (en) 2002-04-02
WO2002024325A3 (en) 2003-01-23
CA2423068A1 (en) 2002-03-28
DE60116794T2 (de) 2006-08-31
EP1337325A2 (de) 2003-08-27
AU2002224336B2 (en) 2007-01-04
EP2263791B1 (de) 2019-09-25
JP2004518411A (ja) 2004-06-24
WO2002024325A2 (en) 2002-03-28
EP2263791A2 (de) 2010-12-22
EP2263791A3 (de) 2012-06-20
EP1337325B1 (de) 2006-01-18
JP4624644B2 (ja) 2011-02-02
ATE315957T1 (de) 2006-02-15

Similar Documents

Publication Publication Date Title
DE60116794D1 (de) Schallausstoss von fluiden aus mehreren behältern
USD491273S1 (en) Hybridization cartridge
DE60039336D1 (de) Fluid-Transport durch Druckvariation zur Analyse biologischer Flüssigkeiten
ATE354440T1 (de) Vorrichtung zum abgeben von flüssigkeit und abgabemethoden
ATE259678T1 (de) Kapillare drucksysteme
DE60141345D1 (de) Vorrichtung zur abgabe von fliessfähigen medien
DE69817203D1 (de) Ventil zur abgabe von flüssigkeit unter schwerkraft
DE60303504D1 (de) Verfahren und vorrichtung zur kontaktlosen tröpfchenabgabe unterhalb einer fluidischen oberfläche
DE60131285D1 (de) Vorrichtung zur wiederholten abgabe von mediendosen
BR0205617B1 (pt) distribuidor de produto fluido.
SE0001790D0 (sv) Hydrophobic barrier
DE60135453D1 (de) Lackiersystem vom kartuschen verwendenden typ
IT1291122B1 (it) Micropompa per la nebulizzazione di fluidi con valvola dosatrice perfezionata
ITMI20031361A0 (it) Processo per la preparazione di distillati medi e basi lube a partireda cariche idrocarburiche sintetiche
IT1298847B1 (it) Valvola per la erogazione dosata di fluidi
DE60209390D1 (de) Vorrichtung zur Bestimmung des Flüssigkeitsvolumens in einer Mikrogravitationsumgebung
DE50113727D1 (de) Veränderung des gehalts an feinchemikalien in organismen durch genetische veränderung des shikimatweges
IT1291123B1 (it) Micropompa perfezionata per la nebulizzazione di fluidi
ITMI20011296A0 (it) Ricarica per l'emanazione di soluzioni e relativo apparecchio emanatore
DE69819364D1 (de) Vorrichtung zur ermöglichung eines luftstroms von einer umgebung zu einem innenraum
ATA4832001A (de) Einrichtung zur reinigung, insbesondere zur filterung, von flüssigkeiten
ITMI20031900A1 (it) Dispositivo per la distribuzione e l'aspirazione uniforme di piccole quantita' di fluidi.
FR2863939B1 (fr) Instrument d'ecriture a jet de liquide
USD523173S1 (en) Liquid and lotion applicator with finger actuated pump
FR2819402B1 (fr) Vernis a ongle contenant un polymere

Legal Events

Date Code Title Description
8364 No opposition during term of opposition