DE60115382D1 - Verfahren zu identifizierung von hiv-epitopen, die durch zytotoxische t-zellen erkannt werden können - Google Patents

Verfahren zu identifizierung von hiv-epitopen, die durch zytotoxische t-zellen erkannt werden können

Info

Publication number
DE60115382D1
DE60115382D1 DE60115382T DE60115382T DE60115382D1 DE 60115382 D1 DE60115382 D1 DE 60115382D1 DE 60115382 T DE60115382 T DE 60115382T DE 60115382 T DE60115382 T DE 60115382T DE 60115382 D1 DE60115382 D1 DE 60115382D1
Authority
DE
Germany
Prior art keywords
cytotoxic
cells
identified
hiv epitopes
identifying hiv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60115382T
Other languages
English (en)
Inventor
Anders Fomsgaard
Soren Brunak
Soren Buus
Sylvie Corbet
Lise Lauemoller
Jan Hansen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Statens Serum Institut SSI
Original Assignee
Statens Serum Institut SSI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Statens Serum Institut SSI filed Critical Statens Serum Institut SSI
Priority claimed from PCT/DK2001/000059 external-priority patent/WO2001055177A2/en
Application granted granted Critical
Publication of DE60115382D1 publication Critical patent/DE60115382D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
DE60115382T 2000-01-28 2001-01-29 Verfahren zu identifizierung von hiv-epitopen, die durch zytotoxische t-zellen erkannt werden können Expired - Lifetime DE60115382D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00610017 2000-01-28
US17933300P 2000-01-31 2000-01-31
PCT/DK2001/000059 WO2001055177A2 (en) 2000-01-28 2001-01-29 Methods to identify ctl epitopes of hiv

Publications (1)

Publication Number Publication Date
DE60115382D1 true DE60115382D1 (de) 2006-01-05

Family

ID=26073685

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60115382T Expired - Lifetime DE60115382D1 (de) 2000-01-28 2001-01-29 Verfahren zu identifizierung von hiv-epitopen, die durch zytotoxische t-zellen erkannt werden können

Country Status (2)

Country Link
US (1) US20040072162A1 (de)
DE (1) DE60115382D1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8706421B2 (en) * 2006-02-16 2014-04-22 Microsoft Corporation Shift-invariant predictions
US20070192033A1 (en) * 2006-02-16 2007-08-16 Microsoft Corporation Molecular interaction predictors
US8396671B2 (en) * 2006-02-16 2013-03-12 Microsoft Corporation Cluster modeling, and learning cluster specific parameters of an adaptive double threading model
US8121797B2 (en) * 2007-01-12 2012-02-21 Microsoft Corporation T-cell epitope prediction
EP2114427B1 (de) 2007-01-30 2014-06-25 New York University Peptide zur behandlung von zuständen im zusammenhang mit stickoxid
US20210319847A1 (en) * 2020-04-14 2021-10-14 Nec Laboratories America, Inc. Peptide-based vaccine generation system
CN113517038A (zh) * 2021-03-02 2021-10-19 阿里巴巴新加坡控股有限公司 药物与靶点之间亲和力的预测方法、装置及设备

Also Published As

Publication number Publication date
US20040072162A1 (en) 2004-04-15

Similar Documents

Publication Publication Date Title
DE60336406D1 (de) Antikörper, die an zellassoziiertes ca 125/0722p binden, und verfahren zu deren anwendung
DE60020163D1 (de) Fotomaske, verfahren zu ihrer herstellung
DE60139212D1 (de) Verfahren zum organisieren, abfragen und navigieren einer datenbank
ATE323796T1 (de) Verfahren zum abtrennen von hemicellulosen aus hemicellulosehaltiger biomasse
DE60121122D1 (de) Verfahren zum Diffusionsfügen von Bauteilen aus Superlegierung
TW200513330A (en) System and method for fabricating a three-dimensional metal object using solid free-form fabrication
DE60102889T2 (de) Wasserlösliche, Wasser- und Ölabweisende Zusammensetzung sowie Verfahren zu ihrer Herstellung
DE69918184D1 (de) Verfahren zum lösen von verklemmten rohren und werkzeugen und hierzu passendes kriechöl
DE60109339D1 (de) Verfahren zum Drahtbonden
DE69923742D1 (de) Verfahren zur Streckformung von ausgehärteten Blechen aus Aluminiumlegierung
ATE459623T1 (de) Pyridoä2,3-düpyrimidine, die sich als hcv- inhibitoren eignen und verfahren zu deren herstellung
DE50106593D1 (de) Verfahren zum abscheiden von insbesondere kristallinen schichten, gaseinlassorgan sowie vorrichtung zur durchführung des verfahrens
NL1020018A1 (nl) Verbeterde terugwinning van koolwaterstof in een Fischer-Tropsch-proces.
DE10194791T1 (de) Verfahren zum Bilden von Halbleiterstrukturen
DE69833800D1 (de) Schmelzklebstoffe aus blockcopolymeren, verfahren zu ihrer herstellung und gegenstände daraus
ATE230726T1 (de) Verfahren um diaryl-pyridine zu herstellen, die als cox-inhibitoren verwendbar sind
DE60132243D1 (de) Verfahren zum indizieren von entitäten
DE60109959D1 (de) Verfahren um die effizienz eines datenstromes in einem kommunikationssystem zu erhöhen
DE60030488D1 (de) Falznahtverbindung, verfahren und vorrichtung zu deren herstellung
DE60110678D1 (de) Vorrichtung zum Fördern von massiven Gegenständen, insbesondere Metallspulen
DE60115382D1 (de) Verfahren zu identifizierung von hiv-epitopen, die durch zytotoxische t-zellen erkannt werden können
DE60141746D1 (de) Feuchttücher, die ionenempfindliche, wasserdispergierbare polymere enthalten und verfahren zu deren herstellung
EA200400455A1 (ru) Способ приготовления быстрорастворимой дозировочной формы
DE60117118D1 (de) Verfahren zur Herstellung von Folie aus Aluminium-Eisen-Legierung
DE50204533D1 (de) Vorrichtung zum einstapeln flacher, biegsamer gegenstaende

Legal Events

Date Code Title Description
8332 No legal effect for de