DE60032908D1 - Zielgerichtete fiberlose radiative effektoren - Google Patents

Zielgerichtete fiberlose radiative effektoren

Info

Publication number
DE60032908D1
DE60032908D1 DE60032908T DE60032908T DE60032908D1 DE 60032908 D1 DE60032908 D1 DE 60032908D1 DE 60032908 T DE60032908 T DE 60032908T DE 60032908 T DE60032908 T DE 60032908T DE 60032908 D1 DE60032908 D1 DE 60032908D1
Authority
DE
Germany
Prior art keywords
targeted
fiberless radiative
radiative effectors
effectors
fiberless
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60032908T
Other languages
English (en)
Other versions
DE60032908T2 (de
Inventor
A Philbert
Ronald Tjalkens
W Aylott
A Clark
E Monson
Raoul Kopelman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Michigan
Original Assignee
University of Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Michigan filed Critical University of Michigan
Application granted granted Critical
Publication of DE60032908D1 publication Critical patent/DE60032908D1/de
Publication of DE60032908T2 publication Critical patent/DE60032908T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0089—Particulate, powder, adsorbate, bead, sphere
    • A61K49/0091—Microparticle, microcapsule, microbubble, microsphere, microbead, i.e. having a size or diameter higher or equal to 1 micrometer
    • A61K49/0093—Nanoparticle, nanocapsule, nanobubble, nanosphere, nanobead, i.e. having a size or diameter smaller than 1 micrometer, e.g. polymeric nanoparticle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
    • A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
    • A61K51/1244—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles
    • A61K51/1251—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles micro- or nanospheres, micro- or nanobeads, micro- or nanocapsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
DE60032908T 1999-08-02 2000-07-26 Zielgerichtete fiberlose radiative effektoren Expired - Fee Related DE60032908T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36631499A 1999-08-02 1999-08-02
US366314 1999-08-02
PCT/US2000/020292 WO2001008660A2 (en) 1999-08-02 2000-07-26 Targeted fiberless radiative effectors

Publications (2)

Publication Number Publication Date
DE60032908D1 true DE60032908D1 (de) 2007-02-22
DE60032908T2 DE60032908T2 (de) 2007-06-28

Family

ID=23442515

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60032908T Expired - Fee Related DE60032908T2 (de) 1999-08-02 2000-07-26 Zielgerichtete fiberlose radiative effektoren

Country Status (4)

Country Link
EP (1) EP1206288B1 (de)
AU (1) AU6376100A (de)
DE (1) DE60032908T2 (de)
WO (1) WO2001008660A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884603B2 (en) 1998-04-03 2005-04-26 The Penn State Research Foundation Nucleic acids encoding IL13 mutants
AU7863900A (en) * 1999-10-06 2001-05-10 Penn State Research Foundation, The Il13 mutants
JP4141385B2 (ja) 2001-10-21 2008-08-27 ソニック グリップ リミテッド 音響放射デバイス
US20040023337A1 (en) * 2001-10-26 2004-02-05 Heavner George A. IL-13 mutein proteins, antibodies, compositions, methods and uses
GB0126236D0 (en) 2001-11-01 2002-01-02 Univ East Anglia Photosensitiser functionalised nanoparticles
EP1465590B1 (de) * 2001-11-02 2008-03-26 The Governors Of The University Of Alberta Micelle-zusammensetzungen enthaltend pegylierten phospholipide und einen photosensibilisator
US7264629B2 (en) 2001-11-09 2007-09-04 Qlt, Inc. Photodynamic therapy for the treatment of hair loss
JP2005513001A (ja) * 2001-11-09 2005-05-12 キュー エル ティー インク． 脱毛治療のための光力学療法
US20050048109A1 (en) * 2003-08-26 2005-03-03 Ceramoptec Industries, Inc. Non-polar photosensitizer formulations for photodynamic therapy
WO2006055638A2 (en) 2004-11-17 2006-05-26 Abgenix, Inc. Fully human monoclonal antibodies to il-13
US8268567B2 (en) 2005-09-16 2012-09-18 The Charles Stark Draper Laboratory Reaction sensing in living cells
US20080044879A1 (en) 2006-08-17 2008-02-21 The Charles Stark Draper Laboratory, Inc. Systems and methods of voltage-gated ion channel assays
WO2010027514A2 (en) 2008-09-08 2010-03-11 The Charles Stark Draper Laboratory, Inc. Coated sensors and methods related thereto
ES2964574T3 (es) * 2009-07-21 2024-04-08 Udo Bogner Sistema de materiales que contiene endoperóxido con adaptación de la desintegración y aplicaciones
CN111450268B (zh) * 2020-05-29 2021-06-01 南京大学 一种基于四氧化三铁的磁共振成像造影剂的制备方法和应用
EP4247850A1 (de) * 2020-11-20 2023-09-27 Simcere Innovation, Inc. Bewaffnete duale car-t-zusammensetzungen und verfahren zur krebsimmuntherapie

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599923A (en) * 1989-03-06 1997-02-04 Board Of Regents, University Of Tx Texaphyrin metal complexes having improved functionalization
US6027726A (en) * 1994-09-30 2000-02-22 Inex Phamaceuticals Corp. Glycosylated protein-liposome conjugates and methods for their preparation
GB9502065D0 (en) * 1995-02-02 1995-03-22 Nycomed Imaging As Contrast media
EP0954336B1 (de) * 1996-06-04 2004-02-25 Pharmacyclics, Inc. Membraneinbau von texaphyrinen
US6143558A (en) * 1997-07-08 2000-11-07 The Regents Of The University Of Michigan Optical fiberless sensors for analyzing cellular analytes
AR022404A1 (es) * 1999-01-25 2002-09-04 Photogen Inc Metodo y agentes para la terapia de radiacion mejorada

Also Published As

Publication number Publication date
WO2001008660A2 (en) 2001-02-08
AU6376100A (en) 2001-02-19
EP1206288A2 (de) 2002-05-22
DE60032908T2 (de) 2007-06-28
WO2001008660A3 (en) 2001-11-22
EP1206288B1 (de) 2007-01-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee