DE60032143D1 - Verwendung von eif4e-bindungsreagenzien in der therapie - Google Patents

Verwendung von eif4e-bindungsreagenzien in der therapie

Info

Publication number
DE60032143D1
DE60032143D1 DE60032143T DE60032143T DE60032143D1 DE 60032143 D1 DE60032143 D1 DE 60032143D1 DE 60032143 T DE60032143 T DE 60032143T DE 60032143 T DE60032143 T DE 60032143T DE 60032143 D1 DE60032143 D1 DE 60032143D1
Authority
DE
Germany
Prior art keywords
therapy
binding reagents
eif4e binding
eif4e
xxyxxx
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60032143T
Other languages
English (en)
Inventor
Christopher Gregory Proud
Terrence Patrick Herbert
David Philip Lane
Robin Fahraeus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Dundee
Original Assignee
University of Dundee
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Dundee filed Critical University of Dundee
Application granted granted Critical
Publication of DE60032143D1 publication Critical patent/DE60032143D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE60032143T 1999-06-21 2000-06-21 Verwendung von eif4e-bindungsreagenzien in der therapie Expired - Lifetime DE60032143D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9914480.0A GB9914480D0 (en) 1999-06-21 1999-06-21 Use of peptides
PCT/GB2000/002414 WO2000078803A2 (en) 1999-06-21 2000-06-21 Use of eif4e binding agents in therapy

Publications (1)

Publication Number Publication Date
DE60032143D1 true DE60032143D1 (de) 2007-01-11

Family

ID=10855771

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60032143T Expired - Lifetime DE60032143D1 (de) 1999-06-21 2000-06-21 Verwendung von eif4e-bindungsreagenzien in der therapie

Country Status (7)

Country Link
US (1) US7141541B1 (de)
EP (1) EP1189936B1 (de)
JP (1) JP2003502440A (de)
AT (1) ATE346863T1 (de)
DE (1) DE60032143D1 (de)
GB (1) GB9914480D0 (de)
WO (1) WO2000078803A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030144190A1 (en) * 1999-12-02 2003-07-31 Nahum Sonenberg Method of modulating and antiapoptotic and antiapoptotic pathways in cells
US6759394B2 (en) 2001-07-26 2004-07-06 Board Of Supervisors Of La. State Un. & Agricultural And Mechanical College Cancer gene therapy based on translational control of a suicide gene
WO2009083188A2 (en) * 2007-12-28 2009-07-09 Fovea Pharmaceuticals Compositions and methods for prophylaxis and treatment of cellular degenerative disorders
FR2942798B1 (fr) * 2009-03-05 2011-04-08 Centre Nat Rech Scient Peptides utilisables pour le traitement de la leucemie lymphoide chronique
SG184860A1 (en) 2010-04-27 2012-11-29 Agency Science Tech & Res Eif4e binding peptides
CN104411715A (zh) * 2012-07-09 2015-03-11 霍夫曼-拉罗奇有限公司 靶向eIF4E的细胞穿透肽
TW202114681A (zh) 2019-07-02 2021-04-16 美商ｅＦＦＥＣＴＯＲ醫療公司 轉譯抑制劑及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994018345A1 (en) 1993-02-05 1994-08-18 Affymax Technologies N.V. Receptor-binding antiproliferative peptides
US5622852A (en) * 1994-10-31 1997-04-22 Washington University Bcl-x/Bcl-2 associated cell death regulator
CA2282827A1 (en) 1997-03-05 1998-09-11 The Regents Of The University Of California Method of alleviating neuropathic pain
US6610508B1 (en) * 1999-03-08 2003-08-26 Anadys Pharmaceuticals, Inc. Translation driver system and methods for use thereof

Also Published As

Publication number Publication date
WO2000078803A3 (en) 2001-07-26
JP2003502440A (ja) 2003-01-21
EP1189936B1 (de) 2006-11-29
US7141541B1 (en) 2006-11-28
GB9914480D0 (en) 1999-08-18
EP1189936A2 (de) 2002-03-27
WO2000078803A2 (en) 2000-12-28
ATE346863T1 (de) 2006-12-15

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Legal Events

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