DE60030483D1 - Ein verfahren zur herstellung von simvastatin - Google Patents

Ein verfahren zur herstellung von simvastatin

Info

Publication number
DE60030483D1
DE60030483D1 DE60030483T DE60030483T DE60030483D1 DE 60030483 D1 DE60030483 D1 DE 60030483D1 DE 60030483 T DE60030483 T DE 60030483T DE 60030483 T DE60030483 T DE 60030483T DE 60030483 D1 DE60030483 D1 DE 60030483D1
Authority
DE
Germany
Prior art keywords
simvastatin
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60030483T
Other languages
English (en)
Other versions
DE60030483T2 (de
Inventor
Kwang Hyuk Lee
Wan Kim
Do Choi
Hun Bae
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CJ CheilJedang Corp
Original Assignee
CJ Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CJ Corp filed Critical CJ Corp
Publication of DE60030483D1 publication Critical patent/DE60030483D1/de
Application granted granted Critical
Publication of DE60030483T2 publication Critical patent/DE60030483T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60030483T 2000-03-30 2000-03-30 Ein verfahren zur herstellung von simvastatin Expired - Lifetime DE60030483T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2000/000283 WO2001072734A1 (en) 2000-03-30 2000-03-30 A process for producing simvastatin

Publications (2)

Publication Number Publication Date
DE60030483D1 true DE60030483D1 (de) 2006-10-12
DE60030483T2 DE60030483T2 (de) 2007-04-26

Family

ID=19198191

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60030483T Expired - Lifetime DE60030483T2 (de) 2000-03-30 2000-03-30 Ein verfahren zur herstellung von simvastatin

Country Status (9)

Country Link
US (1) US6576775B1 (de)
EP (1) EP1268462B1 (de)
JP (1) JP3946521B2 (de)
CN (1) CN1215064C (de)
AU (1) AU2000234636A1 (de)
BR (1) BR0017141B1 (de)
DE (1) DE60030483T2 (de)
MX (1) MXPA02008693A (de)
WO (1) WO2001072734A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100435142B1 (ko) * 2002-01-09 2004-06-09 한미약품 주식회사 개선된 심바스타틴의 제조방법
SI21187A (sl) 2002-03-26 2003-10-31 Krka, Tovarna Zdravil D.D., Novo Mesto Postopek za pripravo 4-oksitetrahidropiran-2-onov
JP2009534459A (ja) 2006-04-26 2009-09-24 ローズモント・フアーマシユーテイカルズ・リミテツド 液体経口組成物
WO2009148709A1 (en) * 2008-04-16 2009-12-10 University Of Utah Research Foundation Pharmacological targeting of vascular malformations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5159104A (en) * 1991-05-01 1992-10-27 Merck & Co., Inc. Process to simvastatin ester
US5393893A (en) * 1993-11-08 1995-02-28 Apotex, Inc. Process for producing simvastatin and analogs thereof
KR100322630B1 (ko) * 1998-09-30 2002-08-21 제일제당주식회사 심바스타틴및 이의 중간체 화합물을 제조하는 방법

Also Published As

Publication number Publication date
CN1451000A (zh) 2003-10-22
US6576775B1 (en) 2003-06-10
EP1268462A4 (de) 2003-05-21
AU2000234636A1 (en) 2001-10-08
EP1268462A1 (de) 2003-01-02
JP3946521B2 (ja) 2007-07-18
JP2003528869A (ja) 2003-09-30
BR0017141B1 (pt) 2011-07-12
DE60030483T2 (de) 2007-04-26
EP1268462B1 (de) 2006-08-30
BR0017141A (pt) 2002-12-17
CN1215064C (zh) 2005-08-17
WO2001072734A1 (en) 2001-10-04
MXPA02008693A (es) 2004-09-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: CJ CHEILJEDANG CORP., SEOUL, KR