DE60026581D1 - Indolderivate zur behandlung von depression und angstzuständen - Google Patents

Indolderivate zur behandlung von depression und angstzuständen

Info

Publication number
DE60026581D1
DE60026581D1 DE60026581T DE60026581T DE60026581D1 DE 60026581 D1 DE60026581 D1 DE 60026581D1 DE 60026581 T DE60026581 T DE 60026581T DE 60026581 T DE60026581 T DE 60026581T DE 60026581 D1 DE60026581 D1 DE 60026581D1
Authority
DE
Germany
Prior art keywords
depression
scareness
treatment
indole derivatives
withdrawal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60026581T
Other languages
English (en)
Other versions
DE60026581T2 (de
Inventor
Martin Hansen
Xiaoqiang He
Allan Honigschmidt
James Koch
Jonathan Kohn
Patrick Rocco
Gianpietro Spinazze
Kumiko Takeuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE60026581D1 publication Critical patent/DE60026581D1/de
Publication of DE60026581T2 publication Critical patent/DE60026581T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
DE60026581T 1999-12-20 2000-12-06 Indolderivate zur behandlung von depression und angstzuständen Expired - Fee Related DE60026581T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17274899P 1999-12-20 1999-12-20
US172748P 1999-12-20
PCT/US2000/032430 WO2001046181A1 (en) 1999-12-20 2000-12-06 Indole derivatives for the treatment of depression and anxiety

Publications (2)

Publication Number Publication Date
DE60026581D1 true DE60026581D1 (de) 2006-05-04
DE60026581T2 DE60026581T2 (de) 2006-12-28

Family

ID=22629052

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60026581T Expired - Fee Related DE60026581T2 (de) 1999-12-20 2000-12-06 Indolderivate zur behandlung von depression und angstzuständen

Country Status (7)

Country Link
US (1) US7144898B2 (de)
EP (1) EP1242411B1 (de)
AT (1) ATE319709T1 (de)
AU (1) AU1930801A (de)
DE (1) DE60026581T2 (de)
ES (1) ES2259619T3 (de)
WO (1) WO2001046181A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100497334C (zh) 2002-06-24 2009-06-10 先灵公司 用作组胺h3拮抗剂的吲哚衍生物
AR070398A1 (es) * 2008-02-22 2010-03-31 Gruenenthal Chemie Derivados sustituidos de indol
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
WO2014144313A1 (en) 2013-03-15 2014-09-18 Carrier Commercial Refrigeration, Inc. Cooking gap control of a cooking apparatus
CN108129251A (zh) * 2017-12-22 2018-06-08 上海应用技术大学 一种2-乙基苯乙烯的合成工艺
CN108314630B (zh) * 2018-02-08 2020-11-06 广西民族大学 一种肟醚类衍生物及其制备方法与应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2337461A1 (de) * 1973-07-24 1975-02-06 Boehringer Mannheim Gmbh Neue indolderivate und verfahren zu deren herstellung
WO1980000152A1 (en) * 1978-07-03 1980-02-07 Sandoz Ag 3-aminopropoxy-aryl derivates,preparation and use thereof
EP0025111B1 (de) 1979-08-10 1984-07-25 Sandoz Ag 3-Aminopropoxyaryl-Derivate, ihre Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
US5300498A (en) * 1993-06-04 1994-04-05 Hoechst-Roussel Pharmaceuticals Incorporated 6-piperazinyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acids, esters, amides and related compounds
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5789402A (en) * 1995-01-17 1998-08-04 Eli Lilly Company Compounds having effects on serotonin-related systems
US5627196A (en) * 1995-01-17 1997-05-06 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5912256A (en) * 1996-06-20 1999-06-15 Eli Lilly And Company Compounds having effects on serotonin-related systems
US6242450B1 (en) * 1998-07-27 2001-06-05 Eli Lilly And Company 5-HT1F antagonists
HUP0102886A3 (en) * 1998-07-27 2002-12-28 Lilly Co Eli Treatment of anxiety disorders
CA2716369C (en) 1999-05-24 2013-05-14 Mitsubishi Tanabe Pharma Corporation Phenoxypropylamine compounds

Also Published As

Publication number Publication date
EP1242411A1 (de) 2002-09-25
DE60026581T2 (de) 2006-12-28
AU1930801A (en) 2001-07-03
US7144898B2 (en) 2006-12-05
WO2001046181A1 (en) 2001-06-28
ES2259619T3 (es) 2006-10-16
ATE319709T1 (de) 2006-03-15
EP1242411B1 (de) 2006-03-08
US20040006229A1 (en) 2004-01-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee