DE60025270D1 - N-substituierte benzyl oder phenyl arylsulfamide und ihre verwendung - Google Patents

N-substituierte benzyl oder phenyl arylsulfamide und ihre verwendung

Info

Publication number
DE60025270D1
DE60025270D1 DE60025270T DE60025270T DE60025270D1 DE 60025270 D1 DE60025270 D1 DE 60025270D1 DE 60025270 T DE60025270 T DE 60025270T DE 60025270 T DE60025270 T DE 60025270T DE 60025270 D1 DE60025270 D1 DE 60025270D1
Authority
DE
Germany
Prior art keywords
aromatic
bis
phenyl
disubstituted
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60025270T
Other languages
English (en)
Other versions
DE60025270T2 (de
Inventor
Donglu Bai
Weizhou Chen
Yunxin Bu
Yiping Wang
Yueli Dong
Aili Kang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Institute of Materia Medica of CAS
Original Assignee
Shanghai Institute of Materia Medica of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Institute of Materia Medica of CAS filed Critical Shanghai Institute of Materia Medica of CAS
Publication of DE60025270D1 publication Critical patent/DE60025270D1/de
Application granted granted Critical
Publication of DE60025270T2 publication Critical patent/DE60025270T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60025270T 1999-12-10 2000-07-03 N-substituierte benzyl oder phenyl arylsulfamide und ihre verwendung Expired - Lifetime DE60025270T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNB99124236XA CN1172908C (zh) 1999-12-10 1999-12-10 N-取代苄基或苯基芳香磺酰胺化合物及其用途
CN99124236 1999-12-10
PCT/CN2000/000187 WO2001042204A1 (fr) 1999-12-10 2000-07-03 Composes sulfamides aromatiques phenyle ou benzyle n-substitues et leurs applications

Publications (2)

Publication Number Publication Date
DE60025270D1 true DE60025270D1 (de) 2006-02-02
DE60025270T2 DE60025270T2 (de) 2006-08-17

Family

ID=5283321

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60025270T Expired - Lifetime DE60025270T2 (de) 1999-12-10 2000-07-03 N-substituierte benzyl oder phenyl arylsulfamide und ihre verwendung

Country Status (7)

Country Link
US (1) US6605635B1 (de)
EP (1) EP1245561B1 (de)
JP (1) JP4015853B2 (de)
CN (1) CN1172908C (de)
AT (1) ATE314345T1 (de)
DE (1) DE60025270T2 (de)
WO (1) WO2001042204A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1358282A1 (de) * 2000-12-15 2003-11-05 Ucb S.A. Oberflächliche funktionalisierung von pigmenten und/oder farbstoffen für strahlungshärtbare druckfarben und lacke
CN102665714A (zh) * 2009-11-17 2012-09-12 沪亚生物国际有限责任公司 心房纤颤的治疗
ES2569123T3 (es) * 2009-11-17 2016-05-06 Huya Bioscience International Llc Infusión lenta de sulcardina y sus sales
KR20210135990A (ko) 2018-12-13 2021-11-16 후야 바이오사이언스 인터내셔널 엘엘씨 급성 심방 세동의 치료를 위한 설카르딘 투여
BR112021014640A8 (pt) 2019-01-29 2022-12-20 Huya Bioscience Int Llc Sais de sulcardina
CA3140046A1 (en) 2019-05-15 2020-11-19 Bexson Biomedical, Inc. Ketamine formulation for subcutaneous injection
WO2021252959A1 (en) * 2020-06-12 2021-12-16 Huyabio International, Llc Sulcardine administration for treatment of acute atrial fibrillation
EP4247340A1 (de) 2020-11-18 2023-09-27 Bexson Biomedical, Inc. Komplexbildnersalzformulierungen von pharmazeutischen verbindungen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059620A (en) 1985-12-27 1991-10-22 The Du Pont Merck Pharmaceutical Company Aryl substituted aminomethyl benzene derivatives

Also Published As

Publication number Publication date
EP1245561A1 (de) 2002-10-02
CN1172908C (zh) 2004-10-27
ATE314345T1 (de) 2006-01-15
JP4015853B2 (ja) 2007-11-28
CN1299813A (zh) 2001-06-20
JP2003516385A (ja) 2003-05-13
WO2001042204A1 (fr) 2001-06-14
DE60025270T2 (de) 2006-08-17
US6605635B1 (en) 2003-08-12
EP1245561B1 (de) 2005-12-28
EP1245561A4 (de) 2003-04-23

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Legal Events

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