DE60021409D1 - Neurokinin b vorläufer aus menschlicher plazenta - Google Patents

Neurokinin b vorläufer aus menschlicher plazenta

Info

Publication number
DE60021409D1
DE60021409D1 DE60021409T DE60021409T DE60021409D1 DE 60021409 D1 DE60021409 D1 DE 60021409D1 DE 60021409 T DE60021409 T DE 60021409T DE 60021409 T DE60021409 T DE 60021409T DE 60021409 D1 DE60021409 D1 DE 60021409D1
Authority
DE
Germany
Prior art keywords
neurokinin
plazenta
preliminary
human
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60021409T
Other languages
English (en)
Other versions
DE60021409T2 (de
Inventor
Nigel Page
Phillip Lowry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Perinatal Diagnostics Ltd Bolden Tyne & Wea Gb
Original Assignee
University of Reading
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Reading filed Critical University of Reading
Application granted granted Critical
Publication of DE60021409D1 publication Critical patent/DE60021409D1/de
Publication of DE60021409T2 publication Critical patent/DE60021409T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/046—Tachykinins, e.g. eledoisins, substance P; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2410/00—Assays, e.g. immunoassays or enzyme assays, involving peptides of less than 20 animo acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE60021409T 1999-11-16 2000-11-10 Neurokinin b vorläufer aus menschlicher plazenta Expired - Lifetime DE60021409T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9927125.6A GB9927125D0 (en) 1999-11-16 1999-11-16 Placental human neurokinin B precursor
GB9927125 1999-11-16
PCT/GB2000/004315 WO2001036979A2 (en) 1999-11-16 2000-11-10 Placental human neurokinin b precursor

Publications (2)

Publication Number Publication Date
DE60021409D1 true DE60021409D1 (de) 2005-08-25
DE60021409T2 DE60021409T2 (de) 2006-05-24

Family

ID=10864633

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60021409T Expired - Lifetime DE60021409T2 (de) 1999-11-16 2000-11-10 Neurokinin b vorläufer aus menschlicher plazenta

Country Status (15)

Country Link
US (1) US7947458B1 (de)
EP (1) EP1229965B1 (de)
JP (1) JP4668501B2 (de)
CN (1) CN1414871A (de)
AT (1) ATE299739T1 (de)
AU (1) AU778423B2 (de)
CA (1) CA2391531A1 (de)
DE (1) DE60021409T2 (de)
ES (1) ES2244480T3 (de)
GB (1) GB9927125D0 (de)
IL (1) IL149598A0 (de)
NO (1) NO330412B1 (de)
NZ (1) NZ519283A (de)
WO (1) WO2001036979A2 (de)
ZA (1) ZA200203880B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6919433B2 (en) 1997-03-14 2005-07-19 Human Genome Sciences, Inc. Antibodies to protein HPMBQ91
EP1333092A3 (de) * 1997-03-14 2003-12-10 Human Genome Sciences, Inc. 28 menschlich sekretierte Proteine
TW202317533A (zh) 2021-07-02 2023-05-01 美商雅斯治療公司 奧沙奈坦(osanetant)之固體形式

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665157A (en) 1985-09-30 1987-05-12 Mcneilab, Inc. Peptide antagonists of neurokinin B
US4742156A (en) * 1985-09-30 1988-05-03 Mcneilab, Inc. Peptide antagonists of neurokinin B and opthalmic solutions containing them
US5331089A (en) 1988-03-25 1994-07-19 Merck Sharpe & Dohme, Ltd. Peptides useful as tachykinin agonists
US5079171A (en) * 1988-09-15 1992-01-07 Adeza Biomedical Corporation Determining pregnancy induced hypertension and eclampsia by immunoassay of cellular fibronectin
PT533280E (pt) 1991-09-20 2001-01-31 Glaxo Group Ltd Novas utilizacoes medicas para antagonistas de taquiquinina
US5328927A (en) 1992-03-03 1994-07-12 Merck Sharpe & Dohme, Ltd. Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them
US5612336A (en) 1992-07-13 1997-03-18 Merck, Sharp & Dohme Ltd. Heterocyclic amide derivatives as tachykinin antagonists
DE69329712T2 (de) 1992-08-13 2001-04-12 Warner Lambert Co Tachykinin antagonistes
US5922681A (en) * 1992-09-14 1999-07-13 Warner-Lambert Company Endothelin antagonists
FR2696178B1 (fr) 1992-09-30 1994-12-30 Sanofi Elf Amides basiques quaternaires, procédé pour leur préparation et compositions pharmaceutiques en contenant.
US5344830A (en) 1992-12-10 1994-09-06 Merck & Co., Inc. N,N-diacylpiperazine tachykinin antagonists
US5543138A (en) * 1994-03-10 1996-08-06 Genetics Institute, Inc. Methods of diagnosing and treating preeclampsia
FR2719311B1 (fr) * 1994-03-18 1998-06-26 Sanofi Sa Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.
US5491140A (en) 1994-06-30 1996-02-13 Eli Lilly And Company Naphthyl tachykinin receptor antagonists to treat physiological conditions
NZ289652A (en) 1994-07-12 1998-05-27 Lilly Co Eli (r)-3-(1h-indol-3-yl)-1-[n-(2-methoxybenzyl)acetylamino]-2-[n-(2-(4-( piperidin-1-yl)piperidin-1-yl)acetyl)amino]propane dihydrochloride trihydrate; non-peptidyl tachykinin receptor antagonistic medicaments
CA2154116A1 (en) 1994-07-22 1996-01-23 Philip Arthur Hipskind 1-aryl-2-acetamidopentanone derivatives for use as tachykinin receptor antagonists
CA2255910A1 (en) * 1996-05-24 1997-11-27 Mitchell Irvin Steinberg Methods of treating hypertension
GB9618931D0 (en) * 1996-09-11 1996-10-23 Univ London Inositol phosphoglycans for therapeutic use in pre-eclampsia and diabetes
US5846973A (en) 1997-05-23 1998-12-08 Eli Lilly And Company Methods of treating pulmonary hypertension
US5985606A (en) 1997-06-19 1999-11-16 Incyte Pharmaceuticals, Inc. Human preprotachykinin B
CA2236489A1 (en) * 1997-07-14 1999-01-14 Human Genome Sciences Novel compounds
EP0892053A3 (de) * 1997-07-14 1999-12-29 Smithkline Beecham Plc Herstellung von rekombinantem HPMBQ91 Polypeptide und dessen Verwendungen
US6689566B1 (en) * 1999-01-14 2004-02-10 Scantibodies Laboratory, Inc. Methods, kits, and antibodies for detecting parathyroid hormone

Also Published As

Publication number Publication date
NO20022276D0 (no) 2002-05-14
DE60021409T2 (de) 2006-05-24
NZ519283A (en) 2004-05-28
GB9927125D0 (en) 2000-01-12
ZA200203880B (en) 2003-08-15
CA2391531A1 (en) 2001-05-25
NO330412B1 (no) 2011-04-11
CN1414871A (zh) 2003-04-30
ATE299739T1 (de) 2005-08-15
US7947458B1 (en) 2011-05-24
AU778423B2 (en) 2004-12-02
NO20022276L (no) 2002-07-05
IL149598A0 (en) 2002-11-10
WO2001036979A2 (en) 2001-05-25
JP2003515138A (ja) 2003-04-22
EP1229965A2 (de) 2002-08-14
EP1229965B1 (de) 2005-07-20
JP4668501B2 (ja) 2011-04-13
AU1289801A (en) 2001-05-30
ES2244480T3 (es) 2005-12-16
WO2001036979A3 (en) 2002-05-02

Similar Documents

Publication Publication Date Title
EP1470146B8 (de) Antikörper gegen das muc18-antigen
CY1112507T1 (el) Μορια αντισωματος που εχουν ειδικοτητα για την ανθρωπινη ιl-1β
IL156618A0 (en) Crystals of whole antibodies and fragments thereof, methods for the preparation thereof and diagnostic kits utilizing the same
TR200002731T2 (tr) Proteolitik antikorların indüktör ve inhibitörlerinin tanımlanması, kompozisyonları ve kullanımları için metotlar
DE59508864D1 (de) MONOKLONALER ANTIKÖRPER GEGEN CD44v6
ATE465257T1 (de) Agonisten für den rezeptor des hepatozyten- wachstumsfaktors und deren anwendungen
HK1074670A1 (en) Sets of digital antibodies directed against short epitopes, and methods using same
TR200002284T2 (tr) Mage ailesinden tümör ile ilgili tümör türevleri
BR0108001A (pt) Moléculas ativadoras de apc com ligação para cd-40
WO2001034801A3 (en) Recombinant gelatin in vaccines
WO2004007743A3 (en) Use of cpg nucleic acids in prion-disease
CY1108645T1 (el) Θεραπεια και διαγνωση νεοπλασματων χρησιμοποιωντας θυμικη στρωματικη λεμφοποιητινη
EP1340981A3 (de) Antikörper zum Nachweis von Amphetamine-Derivaten
NO971341D0 (no) Promoter for reseptor tyrosinkinase TIE
ATE372336T1 (de) Prozess zur herstellung von pioglitazon via verschiedene zwischenstufen
DE60113445D1 (de) Substanzen mit verzweigten linkermolekülen
CA2419698A1 (en) Compounds, antibodies, reagent kits, methods of producing antibodies, and methods of detecting analytes
EP1572225A4 (de) Thrombospondinfragmente und deren verwendung bei klinischen krebs-tests und der erzeugung von antikörpern und sonstigen bindungsmitteln
DE60021409D1 (de) Neurokinin b vorläufer aus menschlicher plazenta
IT1307864B1 (it) Metodo diagnostico per il riconoscimento di neoplasie umane attraversola determinazione dell'isoforma ctn-c della tn-c, frammenti di
WO2004032599A3 (en) Novel immunogenic proteins of leptospira
ATE103989T1 (de) Monoklonale antikoerper gegen e7-protein des humanen papillomvirus typ 16, verfahren zu ihrer herstellung sowie ihre verwendung.
PL400309A1 (pl) Kwasy nukleinowe, proteiny oraz przeciwciala BTL-II
ATE210460T1 (de) Zusammensetzungen, welche adp-ribosyltransferase- aktivität aufweisen und methoden für ihre herstellung und die verwendung derselben
ATE206138T1 (de) Helicobacter pylori antigen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PERINATAL DIAGNOSTICS LTD., BOLDEN, TYNE & WEA, GB