DE60018738D1 - Polyhydroxydiamin tenside und deren verwendung in gentransfer - Google Patents

Polyhydroxydiamin tenside und deren verwendung in gentransfer

Info

Publication number
DE60018738D1
DE60018738D1 DE60018738T DE60018738T DE60018738D1 DE 60018738 D1 DE60018738 D1 DE 60018738D1 DE 60018738 T DE60018738 T DE 60018738T DE 60018738 T DE60018738 T DE 60018738T DE 60018738 D1 DE60018738 D1 DE 60018738D1
Authority
DE
Germany
Prior art keywords
polyhydroxydiamin
gentransfer
tensides
num
carbohydrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60018738T
Other languages
English (en)
Other versions
DE60018738T2 (de
Inventor
Patrick Camilleri
Jan Bernard Frederick Engberts
Matthew Leigh Fielden
Andreas Kremer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Rijksuniversiteit Groningen
Original Assignee
SmithKline Beecham Ltd
Rijksuniversiteit Groningen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd, Rijksuniversiteit Groningen filed Critical SmithKline Beecham Ltd
Publication of DE60018738D1 publication Critical patent/DE60018738D1/de
Application granted granted Critical
Publication of DE60018738T2 publication Critical patent/DE60018738T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
DE60018738T 1999-06-16 2000-06-16 Polyhydroxydiamin-tenside und deren verwendung beim gentransfer Expired - Lifetime DE60018738T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9914085 1999-06-16
GBGB9914085.7A GB9914085D0 (en) 1999-06-16 1999-06-16 New use
PCT/GB2000/002365 WO2000076954A1 (en) 1999-06-16 2000-06-16 Polyhydroxy diamine surfactants and their use in gene transfer

Publications (2)

Publication Number Publication Date
DE60018738D1 true DE60018738D1 (de) 2005-04-21
DE60018738T2 DE60018738T2 (de) 2006-02-02

Family

ID=10855503

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60018738T Expired - Lifetime DE60018738T2 (de) 1999-06-16 2000-06-16 Polyhydroxydiamin-tenside und deren verwendung beim gentransfer

Country Status (9)

Country Link
US (1) US7005300B1 (de)
EP (1) EP1185502B1 (de)
JP (1) JP4794788B2 (de)
AT (1) ATE291007T1 (de)
AU (1) AU5690500A (de)
DE (1) DE60018738T2 (de)
ES (1) ES2239014T3 (de)
GB (1) GB9914085D0 (de)
WO (1) WO2000076954A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080112915A1 (en) * 2003-10-24 2008-05-15 Marianna Foldvari Dna Delivery with Gemini Cationic Surfactants
CN107670583B (zh) * 2017-10-10 2019-04-30 合肥工业大学 一种葡萄糖基双子非离子表面活性剂、两性表面活性剂及其合成方法
CN107673987B (zh) * 2017-10-10 2019-05-03 合肥工业大学 葡萄糖基双子非离子表面活性剂及其合成方法
CN110523539A (zh) * 2019-08-14 2019-12-03 江西理工大学 一种新型表面活性剂在铝土矿反浮选上的应用方法
CN115078739B (zh) * 2022-08-22 2022-11-22 上海执诚生物科技有限公司 一种检测载脂蛋白a1的试剂盒及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5674908A (en) * 1993-12-20 1997-10-07 Life Technologies, Inc. Highly packed polycationic ammonium, sulfonium and phosphonium lipids
US5837533A (en) * 1994-09-28 1998-11-17 American Home Products Corporation Complexes comprising a nucleic acid bound to a cationic polyamine having an endosome disruption agent
WO1997042819A1 (en) * 1996-05-13 1997-11-20 Alberto Haces Cationic lipids for transfection of negatively charged or neutral molecules into living cells
PT1129064E (pt) * 1998-11-12 2008-01-31 Invitrogen Corp Reagentes de transfecção

Also Published As

Publication number Publication date
US7005300B1 (en) 2006-02-28
GB9914085D0 (en) 1999-08-18
ATE291007T1 (de) 2005-04-15
JP2003502307A (ja) 2003-01-21
DE60018738T2 (de) 2006-02-02
ES2239014T3 (es) 2005-09-16
AU5690500A (en) 2001-01-02
EP1185502B1 (de) 2005-03-16
EP1185502A1 (de) 2002-03-13
WO2000076954A1 (en) 2000-12-21
JP4794788B2 (ja) 2011-10-19

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