DE60016614D1 - Zusammensetzungen zur abgabe osteogener proteine - Google Patents

Zusammensetzungen zur abgabe osteogener proteine

Info

Publication number
DE60016614D1
DE60016614D1 DE2000616614 DE60016614T DE60016614D1 DE 60016614 D1 DE60016614 D1 DE 60016614D1 DE 2000616614 DE2000616614 DE 2000616614 DE 60016614 T DE60016614 T DE 60016614T DE 60016614 D1 DE60016614 D1 DE 60016614D1
Authority
DE
Germany
Prior art keywords
delivery
compositions
osteogenic proteins
osteogenic
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE2000616614
Other languages
English (en)
Other versions
DE60016614T2 (de
Inventor
Rebecca Li
Howard Seeherman
John Wozney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetics Institute LLC
Original Assignee
Genetics Institute LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Institute LLC filed Critical Genetics Institute LLC
Publication of DE60016614D1 publication Critical patent/DE60016614D1/de
Application granted granted Critical
Publication of DE60016614T2 publication Critical patent/DE60016614T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/222—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
DE60016614T 1999-10-15 2000-10-13 Zusammensetzungen zur abgabe osteogener proteine Expired - Fee Related DE60016614T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US15970399P 1999-10-15 1999-10-15
US159703P 1999-10-15
US18573400P 2000-02-29 2000-02-29
US185734P 2000-02-29
PCT/US2000/028471 WO2001028603A1 (en) 1999-10-15 2000-10-13 Formulations for delivery of osteogenic proteins

Publications (2)

Publication Number Publication Date
DE60016614D1 true DE60016614D1 (de) 2005-01-13
DE60016614T2 DE60016614T2 (de) 2005-12-22

Family

ID=26856202

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60016614T Expired - Fee Related DE60016614T2 (de) 1999-10-15 2000-10-13 Zusammensetzungen zur abgabe osteogener proteine

Country Status (8)

Country Link
EP (1) EP1220693B1 (de)
JP (1) JP2003512097A (de)
AT (1) ATE284230T1 (de)
AU (1) AU1086601A (de)
DE (1) DE60016614T2 (de)
ES (1) ES2233469T3 (de)
PT (1) PT1220693E (de)
WO (1) WO2001028603A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
SI1448246T2 (sl) 2001-11-19 2015-12-31 Scil Technology Gmbh Postopek za proizvodnjo homogeno obložene naprave, ki ima osteoinduktivne in osteokonduktivne lastnosti
EP2289566A1 (de) 2001-12-21 2011-03-02 Ferrosan Medical Devices A/S Medizinischen Vorrichtung enthaltend ein hämostatisches Mittel und Kit enthaltend die medizinische Vorrichtung
AU2003253049A1 (en) 2002-09-10 2004-04-30 Scil Technology Gmbh Metal implant coated under reduced oxygen concentration with osteoinductive protein
US7927626B2 (en) 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
US20060019868A1 (en) 2004-01-30 2006-01-26 Pendharkar Sanyog M Hemostatic compositions and devices
US8440225B2 (en) 2003-08-07 2013-05-14 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
SI1675608T1 (sl) * 2003-09-12 2007-08-31 Wyeth Corp Injektibilne trdne paličice kalcijevega fosfata za dajanje osteogenih proteinov
CA2558395C (en) 2004-03-10 2011-11-29 Scil Technology Gmbh Coated implants, their manufacturing and use thereof
FR2881651A1 (fr) * 2005-02-09 2006-08-11 Urodelia Sa Nouveau produit pharmaceutique et procede de fabrication de ce produit pharmaceutique
CN102014973A (zh) 2008-02-29 2011-04-13 弗罗桑医疗设备公司 用于促进止血和/或伤口愈合的装置
WO2011143226A1 (en) 2010-05-11 2011-11-17 Howmedica Osteonics Corp. Organophosphorous, multivalent metal compounds, & polymer adhesive interpenetrating network compositions & methods
RU2657955C2 (ru) 2012-03-06 2018-06-18 Ферросан Медикал Дивайсиз А/С Контейнер под давлением, содержащий гемостатическую пасту
EP2825216B1 (de) 2012-06-12 2015-08-19 Ferrosan Medical Devices A/S Trockene blutstillende zusammensetzung
JP6390873B2 (ja) 2013-06-21 2018-09-19 フェッローサン メディカル ディバイス エー／エス 減圧膨張させた乾燥組成物およびそれを保持するためのシリンジ
US10111980B2 (en) 2013-12-11 2018-10-30 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
BR112017007466B1 (pt) 2014-10-13 2021-03-02 Ferrosan Medical Devices A/S método para preparar uma composição seca, método para reconstituir a composição seca, pasta, composição seca, recipiente, kit homeostático, e, uso de uma composição seca
WO2016102446A1 (en) 2014-12-24 2016-06-30 Ferrosan Medical Devices A/S Syringe for retaining and mixing first and second substances
BR112017027695A2 (pt) 2015-07-03 2018-09-04 Ferrosan Medical Devices As seringa para retenção e mistura de primeira e segunda substâncias
CN111278910A (zh) 2017-09-12 2020-06-12 希尔帕医疗保健有限公司 用于膝关节置换术的氨甲环酸喷雾
US10675330B2 (en) 2018-03-21 2020-06-09 Warsaw Orthopedic, Inc. Injectable bone morphogenetic protein
CA3097819A1 (en) 2018-05-09 2019-11-14 Ferrosan Medical Devices A/S Method for preparing a haemostatic composition
US11324806B2 (en) 2018-10-19 2022-05-10 Warsaw Orthopedic, Inc. Sustained delivery of a growth differentiation factor
CN113144277B (zh) * 2021-04-13 2022-06-14 武汉理工大学 一种可注射流体明胶及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6432371A (en) * 1987-07-29 1989-02-02 Nec Corp Inter-processor communicator system
DE69333556T2 (de) * 1992-02-28 2005-06-30 Cohesion Technologies, Inc., Palo Alto Injizierbare keramische Zusammensetzungen sowie Verfahren für ihre Herstellung und Verwendung
EP0906415B1 (de) * 1996-04-19 2009-08-19 Osiris Therapeutics, Inc. Die wiederherstellung und verstärkung von knochen mittels mesenchymalen stammzellen
US20020076429A1 (en) * 1998-01-28 2002-06-20 John F. Wironen Bone paste subjected to irradiative and thermal treatment
CN1094759C (zh) * 1998-12-21 2002-11-27 冶金工业部钢铁研究总院 骨基质明胶载体的去活方法

Also Published As

Publication number Publication date
PT1220693E (pt) 2005-02-28
AU1086601A (en) 2001-04-30
WO2001028603A1 (en) 2001-04-26
JP2003512097A (ja) 2003-04-02
ES2233469T3 (es) 2005-06-16
ATE284230T1 (de) 2004-12-15
EP1220693B1 (de) 2004-12-08
EP1220693A1 (de) 2002-07-10
DE60016614T2 (de) 2005-12-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee