DE60001737D1 - Verfahren zur herstellung von beta-laktamderivaten - Google Patents

Verfahren zur herstellung von beta-laktamderivaten

Info

Publication number
DE60001737D1
DE60001737D1 DE60001737T DE60001737T DE60001737D1 DE 60001737 D1 DE60001737 D1 DE 60001737D1 DE 60001737 T DE60001737 T DE 60001737T DE 60001737 T DE60001737 T DE 60001737T DE 60001737 D1 DE60001737 D1 DE 60001737D1
Authority
DE
Germany
Prior art keywords
extraction
acid
glutaryl
producing beta
lactam derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60001737T
Other languages
English (en)
Other versions
DE60001737T2 (de
Inventor
Enrico Siviero
Walter Cabri
Mario Terrassan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olon SpA
Original Assignee
Antibioticos SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antibioticos SpA filed Critical Antibioticos SpA
Application granted granted Critical
Publication of DE60001737D1 publication Critical patent/DE60001737D1/de
Publication of DE60001737T2 publication Critical patent/DE60001737T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/02—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60001737T 1999-05-21 2000-05-16 Verfahren zur herstellung von beta-laktamderivaten Expired - Fee Related DE60001737T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI001120A IT1312567B1 (it) 1999-05-21 1999-05-21 Processo per la sintesi di derivati beta-lattamici.
PCT/EP2000/004372 WO2000071547A1 (en) 1999-05-21 2000-05-16 A PROCESS FOR THE PREPARATION OF β-LACTAM DERIVATIVES

Publications (2)

Publication Number Publication Date
DE60001737D1 true DE60001737D1 (de) 2003-04-24
DE60001737T2 DE60001737T2 (de) 2003-10-16

Family

ID=11383012

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60001737T Expired - Fee Related DE60001737T2 (de) 1999-05-21 2000-05-16 Verfahren zur herstellung von beta-laktamderivaten

Country Status (14)

Country Link
US (2) US6458558B1 (de)
EP (1) EP1178991B1 (de)
KR (1) KR20020033624A (de)
CN (1) CN1351605A (de)
AT (1) ATE234844T1 (de)
AU (1) AU5066100A (de)
CA (1) CA2374686A1 (de)
DE (1) DE60001737T2 (de)
DK (1) DK1178991T3 (de)
ES (1) ES2193962T3 (de)
IT (1) IT1312567B1 (de)
PT (1) PT1178991E (de)
TR (1) TR200103306T2 (de)
WO (1) WO2000071547A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102093390B (zh) * 2011-01-27 2012-08-22 蚌埠丰原涂山制药有限公司 一种制备头孢呋辛酸的方法
CN104230957B (zh) * 2013-06-09 2017-02-08 广东立国制药有限公司 头孢呋辛酸的制备方法及该过程中去除dcc内酯的方法
CN104072516A (zh) * 2014-06-18 2014-10-01 珠海保税区丽珠合成制药有限公司 一种合成头孢呋辛酸的方法
CN106565748B (zh) * 2016-09-30 2019-03-22 华北制药河北华民药业有限责任公司 头孢呋辛钠及其制剂的制备方法
KR102651647B1 (ko) 2019-03-12 2024-03-26 루머스 리미티드 이미지 프로젝터
CN115176458B (zh) 2020-04-20 2024-06-07 鲁姆斯有限公司 具有增强的激光效率和眼睛安全的近眼显示器
WO2022130393A1 (en) 2020-12-20 2022-06-23 Lumus Ltd. Image projector with laser scanning over spatial light modulator

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2020792A6 (es) * 1990-08-03 1991-09-16 Antibioticos Sa Un procedimiento enzimatico para la presentacion de acido 7-amino-cefa-losporanico y un procedimiento para expresar la enzima 7b (4-carboxibutanamido) cefalosporinacilasa.
IT1252308B (it) * 1990-12-21 1995-06-08 Antibioticos Spa Procedimento enzimatico per la produzione di acido 7- amminocefalosporanico e derivati
AU3661597A (en) * 1996-07-29 1998-02-20 Bristol-Myers Squibb Company Solvent extraction of 3-hydroxymethylcephalosporins
KR100187959B1 (ko) * 1997-03-31 1999-06-01 윤재승 저융점 무정형 세푸록심 악세틸의 제조방법

Also Published As

Publication number Publication date
IT1312567B1 (it) 2002-04-22
TR200103306T2 (tr) 2002-05-21
EP1178991B1 (de) 2003-03-19
DE60001737T2 (de) 2003-10-16
EP1178991A1 (de) 2002-02-13
ITMI991120A1 (it) 2000-11-21
PT1178991E (pt) 2003-06-30
WO2000071547A1 (en) 2000-11-30
DK1178991T3 (da) 2003-07-14
CA2374686A1 (en) 2000-11-30
CN1351605A (zh) 2002-05-29
ES2193962T3 (es) 2003-11-16
ATE234844T1 (de) 2003-04-15
US20030004336A1 (en) 2003-01-02
AU5066100A (en) 2000-12-12
KR20020033624A (ko) 2002-05-07
US6458558B1 (en) 2002-10-01

Similar Documents

Publication Publication Date Title
KR970701786A (ko) 스트렙토마이세스 sp. P 6621 FERM P 2804의 발효액으로부터 클라불란산과 제약학적으로 허용가능한 이들의 염을 단리하는 신규한 방법(NOVEL PROCESS FOR THE ISOLATION OF CLAVULANIC ACID AND OF PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF FROM THE FERMENTATION BROTH OF STREPTOMYCES SP. P 6621 FERM P 2804)
DE60001737T2 (de) Verfahren zur herstellung von beta-laktamderivaten
US4389489A (en) Optically pure heterocyclic aminoacid compounds, a process for their use for the synthesis of medicaments
EP0977883B1 (de) Verbessertes verfahren zur fermentativer herstellung von penizillin
ATE183778T1 (de) Verfahren zur herstellung von cephalosporinen
ATE160589T1 (de) Verfahren zur enzymatischen herstellung von beta- lactam derivaten und abtrennung von d- phenylglycine amid
WO1998004565A1 (en) Solvent extraction of 3-hydroxymethylcephalosporins
ATE288962T1 (de) Verbessertes verfahren zur fermentativen herstellung von cephalosporin
ATE319785T1 (de) Verfahren zur herstellung von farbmitteln
EP0336511A2 (de) Verfahren zum Schutz von Carboxyl-Gruppen in der Chemie von beta-Lactamverbindungen
RU93004674A (ru) Способ получения цефалоспоринов
ITMI931954A0 (it) Metodo per produrre acido 7-amminocefalosporanico per bioconversione diretta mediante enzimi liberi recuperati per ultrafiltrazione e reimpiegati della soluzione permeata dall'ultrafiltrazione di brodocoltura harvest di cefalosporina c.
IT9022512A1 (it) Procedimento enzimatico per la produzione di acido 7b- (4carbossibutanamido) cefalosporanici.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee