DE3889964D1 - Verfahren und Zusammensetzung zur Behandlung und Vorbeugung von Virus-Infektionen. - Google Patents

Verfahren und Zusammensetzung zur Behandlung und Vorbeugung von Virus-Infektionen.

Info

Publication number
DE3889964D1
DE3889964D1 DE3889964T DE3889964T DE3889964D1 DE 3889964 D1 DE3889964 D1 DE 3889964D1 DE 3889964 T DE3889964 T DE 3889964T DE 3889964 T DE3889964 T DE 3889964T DE 3889964 D1 DE3889964 D1 DE 3889964D1
Authority
DE
Germany
Prior art keywords
treatment
prevention
composition
virus infections
steroids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3889964T
Other languages
English (en)
Other versions
DE3889964T2 (de
Inventor
Anthony Atkinson
Graham Lloyd
Peter Morgan Sutton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbiological Research Authority
Original Assignee
HEALTH LAB SERVICE BOARD
Public Health Laboratory Service Board
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HEALTH LAB SERVICE BOARD, Public Health Laboratory Service Board filed Critical HEALTH LAB SERVICE BOARD
Application granted granted Critical
Publication of DE3889964D1 publication Critical patent/DE3889964D1/de
Publication of DE3889964T2 publication Critical patent/DE3889964T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
DE3889964T 1987-03-17 1988-03-16 Verfahren und Zusammensetzung zur Behandlung und Vorbeugung von Virus-Infektionen. Expired - Fee Related DE3889964T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878706313A GB8706313D0 (en) 1987-03-17 1987-03-17 Treatment & prevention of viral infections

Publications (2)

Publication Number Publication Date
DE3889964D1 true DE3889964D1 (de) 1994-07-14
DE3889964T2 DE3889964T2 (de) 1994-09-15

Family

ID=10614085

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3889964T Expired - Fee Related DE3889964T2 (de) 1987-03-17 1988-03-16 Verfahren und Zusammensetzung zur Behandlung und Vorbeugung von Virus-Infektionen.

Country Status (10)

Country Link
US (1) US4957910A (de)
EP (1) EP0285285B1 (de)
JP (1) JPS63301823A (de)
AT (1) ATE106729T1 (de)
AU (1) AU619174B2 (de)
CA (1) CA1317224C (de)
DE (1) DE3889964T2 (de)
DK (1) DK143088A (de)
GB (1) GB8706313D0 (de)
ZA (1) ZA881856B (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO178843C (no) * 1988-07-11 1996-06-19 Sspl Sa Safe Sex Prod Licens Fremgangsmåte for fremstilling av et farmasöytisk preparat for å forhindre seksuelt overförbare sykdommer
EP0435926A1 (de) * 1988-09-20 1991-07-10 FISONS plc Gallensäuren zur behandlung von viralen infektionen
DK603988D0 (da) * 1988-10-28 1988-10-28 Klaus Bendtzen Farmaceutisk praeparat
US5079240A (en) * 1990-03-15 1992-01-07 The Regents Of The University Of California Synthetic conjugated bile acid and method of use thereof
US5206008A (en) * 1991-04-15 1993-04-27 Virginia Commonwealth University Enhancement of immune response
IT1255450B (it) * 1992-06-30 1995-10-31 Montefarmaco Spa Uso di acidi biliari come agenti antivirali
CA2156717C (en) * 1993-02-23 2001-05-29 Daniel E. Kahne Solution and solid-phase formation of glycosidic linkages
US5639866A (en) * 1993-02-23 1997-06-17 Princeton University Single-step formation of multiple glycosidic linkages
DE4316347C1 (de) * 1993-02-26 1994-08-18 Ina Dr Levi Verfahren zur Herstellung einer pharmazeutischen Zubereitung und Verwendung derselben zur Behandlung bestimmter Erkrankungen
EP0773029A4 (de) * 1993-07-19 1997-09-03 Tokyo Tanabe Co Inhibitor der hepatitis-c-virus-proliferation
US6551623B1 (en) 1993-09-09 2003-04-22 Lorus Therapeutics Inc. Immunomodulating compositions from bile
ES2207639T3 (es) * 1993-09-09 2004-06-01 Lorus Therapeutics Inc. Composiciones modulares inmunologicas a partir de las bilis.
US5658560A (en) * 1994-01-18 1997-08-19 Serikov; Vladimir B. Method of treating endotoxemia by administering tyloxapol
US5646316A (en) * 1994-04-08 1997-07-08 Osteoarthritis Sciences, Inc. Bile acid inhibitors of metalloproteinase enzymes
AU711294B2 (en) 1995-03-16 1999-10-07 Erin Mills Biotech Inc. Immunomodulating compositions from bile for the treatment of immune system disorders
IT1282943B1 (it) * 1995-12-27 1998-04-02 Sanofi Winthrop S P A Composizione farmaceutica iniettabile__a base di acido ursodesossicoli co o tauroursodesossicolico
DE19631122A1 (de) * 1996-08-01 1998-02-05 Falk Pharma Gmbh Verwendung von Ursodeoxycholsäure bei HIV-Infektion
US7169889B1 (en) 1999-06-19 2007-01-30 Biocon Limited Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin
EP1333847A1 (de) * 2000-11-08 2003-08-13 Lorus Therapeutics Inc. Kombinationpräparate enthltend biologische verhaltensändernde stoffe und krebsmittel und ihre verwendung
KR20030005204A (ko) * 2000-12-25 2003-01-17 가부시키가이샤 시세이도 교감신경 활성화 향료 조성물
US7060675B2 (en) 2001-02-15 2006-06-13 Nobex Corporation Methods of treating diabetes mellitus
US6867183B2 (en) 2001-02-15 2005-03-15 Nobex Corporation Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US7713932B2 (en) 2001-06-04 2010-05-11 Biocon Limited Calcitonin drug-oligomer conjugates, and uses thereof
US6835802B2 (en) * 2001-06-04 2004-12-28 Nobex Corporation Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
US6828297B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6828305B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6713452B2 (en) * 2001-06-04 2004-03-30 Nobex Corporation Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6858580B2 (en) * 2001-06-04 2005-02-22 Nobex Corporation Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
EP1399140A1 (de) * 2001-06-20 2004-03-24 Lorus Therapeutics Inc. Immunmodulatorische zusammensetzungen und deren anwendung
US7053076B2 (en) 2001-08-29 2006-05-30 Xenoport, Inc. Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs
US6770625B2 (en) * 2001-09-07 2004-08-03 Nobex Corporation Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
US7166571B2 (en) * 2001-09-07 2007-01-23 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US6913903B2 (en) 2001-09-07 2005-07-05 Nobex Corporation Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US7312192B2 (en) * 2001-09-07 2007-12-25 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US7030082B2 (en) * 2001-09-07 2006-04-18 Nobex Corporation Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
US7196059B2 (en) 2001-09-07 2007-03-27 Biocon Limited Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US7601688B2 (en) * 2002-06-13 2009-10-13 Biocon Limited Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus
CA2580313C (en) 2004-07-19 2016-03-15 Biocon Limited Insulin-oligomer conjugates, formulations and uses thereof
CN101939023B (zh) 2007-10-16 2016-08-03 百康有限公司 可经口给药的固体药物组合物及其方法
CN103570790B (zh) * 2012-08-07 2016-06-01 中国科学院上海药物研究所 原人参二醇衍生物及其制备方法、包含该衍生物的组合物及其用途
US11072630B2 (en) 2015-03-10 2021-07-27 Metselex, Inc. Fluorinated and alkylated bile acids
US11534420B2 (en) 2019-05-14 2022-12-27 Tyme, Inc. Compositions and methods for treating cancer
US10905698B1 (en) 2020-05-14 2021-02-02 Tyme, Inc. Methods of treating SARS-COV-2 infections
WO2021231931A1 (en) * 2020-05-14 2021-11-18 Tyme, Inc. Methods of treating sars-cov-2 infections

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE44263B1 (en) * 1975-12-03 1981-09-23 Leo Pharm Prod Ltd New fusidic acid derivatives
GB8417895D0 (en) * 1984-07-13 1984-08-15 Marples B A Pharmaceutical anti-fungal composition

Also Published As

Publication number Publication date
EP0285285A2 (de) 1988-10-05
DK143088A (da) 1988-09-18
ZA881856B (en) 1989-04-26
US4957910A (en) 1990-09-18
AU619174B2 (en) 1992-01-23
JPS63301823A (ja) 1988-12-08
DE3889964T2 (de) 1994-09-15
EP0285285A3 (en) 1990-12-05
CA1317224C (en) 1993-05-04
DK143088D0 (da) 1988-03-16
ATE106729T1 (de) 1994-06-15
EP0285285B1 (de) 1994-06-08
GB8706313D0 (en) 1987-04-23
AU1321688A (en) 1988-09-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee
8327 Change in the person/name/address of the patent owner

Owner name: MICROBIOLOGICAL RESEARCH AUTHORITY, SALISBURY, GB