DE3888541T2 - Verbesserung der toxizitätskurven in der chemotherapie. - Google Patents

Verbesserung der toxizitätskurven in der chemotherapie.

Info

Publication number
DE3888541T2
DE3888541T2 DE3888541T DE3888541T DE3888541T2 DE 3888541 T2 DE3888541 T2 DE 3888541T2 DE 3888541 T DE3888541 T DE 3888541T DE 3888541 T DE3888541 T DE 3888541T DE 3888541 T2 DE3888541 T2 DE 3888541T2
Authority
DE
Germany
Prior art keywords
chemotherapy
improvement
toxicity curves
toxicity
curves
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3888541T
Other languages
English (en)
Other versions
DE3888541D1 (de
Inventor
Philip Schein
James Piper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
U S BIOSCIENCE BLUE BELL
Original Assignee
U S BIOSCIENCE BLUE BELL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by U S BIOSCIENCE BLUE BELL filed Critical U S BIOSCIENCE BLUE BELL
Application granted granted Critical
Publication of DE3888541D1 publication Critical patent/DE3888541D1/de
Publication of DE3888541T2 publication Critical patent/DE3888541T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/10Expectorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE3888541T 1987-12-22 1988-12-15 Verbesserung der toxizitätskurven in der chemotherapie. Expired - Lifetime DE3888541T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13672187A 1987-12-22 1987-12-22
PCT/US1988/004445 WO1989005637A1 (en) 1987-12-22 1988-12-15 Improving toxicity profiles in chemotherapy

Publications (2)

Publication Number Publication Date
DE3888541D1 DE3888541D1 (de) 1994-04-21
DE3888541T2 true DE3888541T2 (de) 1994-06-23

Family

ID=22474077

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3888541T Expired - Lifetime DE3888541T2 (de) 1987-12-22 1988-12-15 Verbesserung der toxizitätskurven in der chemotherapie.

Country Status (6)

Country Link
EP (1) EP0391971B1 (de)
JP (1) JP2951344B2 (de)
AU (1) AU629533B2 (de)
CA (1) CA1328619C (de)
DE (1) DE3888541T2 (de)
WO (1) WO1989005637A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5567686A (en) * 1992-03-13 1996-10-22 Arch Development Corporation Method for protection against genotoxic mutagenesis
US5869338A (en) * 1992-03-13 1999-02-09 Arch Development Corporation Method for protection against genotoxic mutagenesis
US5260340A (en) * 1992-11-19 1993-11-09 Baranowitz Steven A Prevention and amelioration of acetaminophen toxicity with beta-carotene
US6573253B2 (en) 1997-02-12 2003-06-03 Medimmune Oncology Inc. Methods for the administration of amifostine and related compounds
US5994409A (en) 1997-12-09 1999-11-30 U.S. Bioscience, Inc. Methods for treatment of neuro--and nephro--disorders and therapeutic toxicities using aminothiol compounds
US6384259B1 (en) 1998-11-16 2002-05-07 Medimmune Oncology, Inc. Stable amorphous amifostine compositions and dosage form
US7053072B2 (en) 2001-05-11 2006-05-30 Medimmune Oncology, Inc. Methods for the administration of amifostine and related compounds
US6863718B2 (en) 2001-10-31 2005-03-08 Silberline Manufacturing Co., Inc. Phosphonic acid derivative treatment of metallic flakes
US7629333B2 (en) 2002-03-29 2009-12-08 Medimmune, Llc Stable amorphous amifostine compositions and methods for the preparation and use of same
US7345018B2 (en) 2002-04-25 2008-03-18 Reception Aps Method of treating side effects induced by therapeutic agents
CN100441175C (zh) * 2003-03-26 2008-12-10 里斯普蒂康公司 化合物用于制备预防药物诱导的细胞毒性药物的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3892824A (en) * 1968-12-16 1975-07-01 Southern Res Inst S-{107 -({107 -aminoalkylamino)alkyl dihydrogen phosphorothioates
US4424216A (en) * 1979-07-31 1984-01-03 The Rockefeller University Method for the reduction of mucin viscosity
US4314989A (en) * 1980-05-07 1982-02-09 Rosen Gerald M Methionine sulfoxide amflioration of acetaminophen toxicity
US4676979A (en) * 1984-12-31 1987-06-30 Eastern Virginia Medical Authority/Med. Ctr. Hosp. Method of protecting animals against ionizing radiation

Also Published As

Publication number Publication date
JP2951344B2 (ja) 1999-09-20
AU629533B2 (en) 1992-10-08
EP0391971A1 (de) 1990-10-17
CA1328619C (en) 1994-04-19
EP0391971B1 (de) 1994-03-16
EP0391971A4 (en) 1991-10-02
AU2922389A (en) 1989-07-19
DE3888541D1 (de) 1994-04-21
JPH03503162A (ja) 1991-07-18
WO1989005637A1 (en) 1989-06-29

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Legal Events

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8364 No opposition during term of opposition