DE3887611T2 - Butensäure-Amide, deren Salze, diese enthaltende pharmazeutische Zusammensetzungen und Verfahren zu deren Herstellung. - Google Patents

Butensäure-Amide, deren Salze, diese enthaltende pharmazeutische Zusammensetzungen und Verfahren zu deren Herstellung.

Info

Publication number
DE3887611T2
DE3887611T2 DE88308831T DE3887611T DE3887611T2 DE 3887611 T2 DE3887611 T2 DE 3887611T2 DE 88308831 T DE88308831 T DE 88308831T DE 3887611 T DE3887611 T DE 3887611T DE 3887611 T2 DE3887611 T2 DE 3887611T2
Authority
DE
Germany
Prior art keywords
salts
processes
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88308831T
Other languages
English (en)
Other versions
DE3887611D1 (de
Inventor
Tamas Fodor
Laszlo Dobay
Janos Fischer
Bela Stefko
Elemer Ezer
Katalin Saghy
Laszlo Szporny
Judit Matuz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of DE3887611D1 publication Critical patent/DE3887611D1/de
Application granted granted Critical
Publication of DE3887611T2 publication Critical patent/DE3887611T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
    • C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C235/78—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE88308831T 1987-09-25 1988-09-23 Butensäure-Amide, deren Salze, diese enthaltende pharmazeutische Zusammensetzungen und Verfahren zu deren Herstellung. Expired - Fee Related DE3887611T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU874302A HU198446B (en) 1987-09-25 1987-09-25 Process for production of new amids of buten acid and medical compositions containing such active substances

Publications (2)

Publication Number Publication Date
DE3887611D1 DE3887611D1 (de) 1994-03-17
DE3887611T2 true DE3887611T2 (de) 1994-05-11

Family

ID=10967585

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88308831T Expired - Fee Related DE3887611T2 (de) 1987-09-25 1988-09-23 Butensäure-Amide, deren Salze, diese enthaltende pharmazeutische Zusammensetzungen und Verfahren zu deren Herstellung.

Country Status (11)

Country Link
US (1) US4923888A (de)
EP (1) EP0309261B1 (de)
JP (1) JPH01156949A (de)
KR (1) KR930006195B1 (de)
CN (1) CN1015452B (de)
AT (1) ATE101119T1 (de)
CA (1) CA1328277C (de)
DE (1) DE3887611T2 (de)
ES (1) ES2063045T3 (de)
HU (1) HU198446B (de)
SU (1) SU1711671A3 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU209487B (en) * 1991-12-19 1994-06-28 Richter Gedeon Vegyeszet Process for producing tetrahydro-naphtaline derivatives and pharmaceutical compositions containing them as active agents
HU210698B (en) * 1992-12-23 1995-08-28 Richter Gedeon Vegyeszet Process to prepare the novel 4-(4-hidroxy-3-nitro-phenyl)-4-oxo butenic acid and its salt and pharmaceutical compositions to prepare them

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1193955B (it) * 1980-07-22 1988-08-31 Real Di Alberto Reiner S A S Derivati ammidici dell'acido p-isobutilfenilpropionico, procedimento per la loro preparazione e relative composizioni farmaceutici
FR2504127B1 (fr) * 1981-04-17 1985-07-19 Roussel Uclaf Nouveaux derives d'acides phenyl aliphatique carboxyliques, procede pour leur preparation et leur application comme medicaments
EP0099960B1 (de) * 1982-07-20 1985-04-10 EPROVA AG Forschungsinstitut Verfahren zur Herstellung von Niederalkylestern von N-L-alpha-Aspartyl-L-phenylalanin und neue Zwischenprodukte zu deren Herstellung
CA1277993C (en) * 1986-03-27 1990-12-18 Kazuhiko Yamada N2-(1-carboxy-3-oxo-3-phenylpropyl)-l-lysine compounds and their derivatives
HU198294B (en) * 1987-06-10 1989-09-28 Richter Gedeon Vegyeszet Process for producing butenoic acid amides and pharmaceutical compositions comprising such active ingredient

Also Published As

Publication number Publication date
HUT47900A (en) 1989-04-28
EP0309261A2 (de) 1989-03-29
EP0309261B1 (de) 1994-02-02
CN1033044A (zh) 1989-05-24
DE3887611D1 (de) 1994-03-17
KR930006195B1 (ko) 1993-07-08
ES2063045T3 (es) 1995-01-01
SU1711671A3 (ru) 1992-02-07
EP0309261A3 (en) 1990-06-13
JPH01156949A (ja) 1989-06-20
CN1015452B (zh) 1992-02-12
HU198446B (en) 1989-10-30
US4923888A (en) 1990-05-08
KR890005032A (ko) 1989-05-11
ATE101119T1 (de) 1994-02-15
CA1328277C (en) 1994-04-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee