DE3883596T2 - Reinigung von rekombiniertem Hepatitis-B-Oberflächen-Antigen. - Google Patents

Reinigung von rekombiniertem Hepatitis-B-Oberflächen-Antigen.

Info

Publication number
DE3883596T2
DE3883596T2 DE88301779T DE3883596T DE3883596T2 DE 3883596 T2 DE3883596 T2 DE 3883596T2 DE 88301779 T DE88301779 T DE 88301779T DE 3883596 T DE3883596 T DE 3883596T DE 3883596 T2 DE3883596 T2 DE 3883596T2
Authority
DE
Germany
Prior art keywords
antigen
purification
surface antigen
yeast
daltons
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88301779T
Other languages
English (en)
Other versions
DE3883596D1 (de
Inventor
William M Hurni
Dennis J Kubek
William J Miller
Mark S Rienstra
Edward M Scolnick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE3883596D1 publication Critical patent/DE3883596D1/de
Application granted granted Critical
Publication of DE3883596T2 publication Critical patent/DE3883596T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
DE88301779T 1987-03-09 1988-03-01 Reinigung von rekombiniertem Hepatitis-B-Oberflächen-Antigen. Expired - Fee Related DE3883596T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2334787A 1987-03-09 1987-03-09

Publications (2)

Publication Number Publication Date
DE3883596D1 DE3883596D1 (de) 1993-10-07
DE3883596T2 true DE3883596T2 (de) 1994-02-17

Family

ID=21814559

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88301779T Expired - Fee Related DE3883596T2 (de) 1987-03-09 1988-03-01 Reinigung von rekombiniertem Hepatitis-B-Oberflächen-Antigen.

Country Status (10)

Country Link
EP (1) EP0291146B1 (de)
JP (1) JPS63270629A (de)
AT (1) ATE93891T1 (de)
AU (1) AU608813B2 (de)
CA (1) CA1304887C (de)
CY (1) CY1790A (de)
DE (1) DE3883596T2 (de)
DK (1) DK123288A (de)
ES (1) ES2043808T3 (de)
HK (1) HK48094A (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960023066A (ko) * 1994-12-10 1996-07-18 성재갑 전에스 (s) 2 펩티드 함유 비 (b) 형 간염 표면항원의 정제 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL69202A (en) * 1982-09-08 1991-08-16 Smith Kline Rit Surface antigen polypeptides of hbv virus produced in yeast and the preparation thereof
EP0401941A3 (de) * 1984-07-11 1991-04-17 Takeda Chemical Industries, Ltd. Hepatitis B-Virus-Oberflächen-Antigen und seine Herstellung
US4895800A (en) * 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen
JPS62298536A (ja) * 1986-06-17 1987-12-25 Green Cross Corp:The 生理活性物質の自動精製方法および自動精製装置
DE3882154T2 (de) * 1987-02-27 1993-12-02 Merck & Co Inc Verfahren zur Herstellung des pres 1/S2/S-Hepatitis-B-Antigens aus Hefe.

Also Published As

Publication number Publication date
HK48094A (en) 1994-05-20
JPS63270629A (ja) 1988-11-08
AU1277888A (en) 1988-09-08
EP0291146B1 (de) 1993-09-01
ES2043808T3 (es) 1994-01-01
ATE93891T1 (de) 1993-09-15
AU608813B2 (en) 1991-04-18
CA1304887C (en) 1992-07-07
DE3883596D1 (de) 1993-10-07
EP0291146A3 (en) 1989-12-06
DK123288D0 (da) 1988-03-08
CY1790A (en) 1995-10-20
EP0291146A2 (de) 1988-11-17
DK123288A (da) 1988-09-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee