DE3883478D1 - Peridinin-Chlorophyll-Komplex als fluoreszierende Erkennungszeichen. - Google Patents

Peridinin-Chlorophyll-Komplex als fluoreszierende Erkennungszeichen.

Info

Publication number
DE3883478D1
DE3883478D1 DE88309940T DE3883478T DE3883478D1 DE 3883478 D1 DE3883478 D1 DE 3883478D1 DE 88309940 T DE88309940 T DE 88309940T DE 3883478 T DE3883478 T DE 3883478T DE 3883478 D1 DE3883478 D1 DE 3883478D1
Authority
DE
Germany
Prior art keywords
peridinin
pair
chlorophyll
fluorescent
chlorophyll complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE88309940T
Other languages
English (en)
Other versions
DE3883478T2 (de
Inventor
Diether J Recktenwald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of DE3883478D1 publication Critical patent/DE3883478D1/de
Application granted granted Critical
Publication of DE3883478T2 publication Critical patent/DE3883478T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/802—Chromogenic or luminescent peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE88309940T 1987-10-21 1988-10-21 Peridinin-Chlorophyll-Komplex als fluoreszierende Erkennungszeichen. Expired - Lifetime DE3883478T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/111,209 US4876190A (en) 1987-10-21 1987-10-21 Peridinin-chlorophyll complex as fluorescent label

Publications (2)

Publication Number Publication Date
DE3883478D1 true DE3883478D1 (de) 1993-09-30
DE3883478T2 DE3883478T2 (de) 1994-02-17

Family

ID=22337182

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88309940T Expired - Lifetime DE3883478T2 (de) 1987-10-21 1988-10-21 Peridinin-Chlorophyll-Komplex als fluoreszierende Erkennungszeichen.

Country Status (6)

Country Link
US (1) US4876190A (de)
EP (1) EP0314406B1 (de)
JP (1) JPH0614043B2 (de)
AT (1) ATE93628T1 (de)
DE (1) DE3883478T2 (de)
ES (1) ES2059533T3 (de)

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US5224058A (en) * 1990-05-01 1993-06-29 Becton, Dickinson And Company Method for data transformation
IE76732B1 (en) * 1990-08-07 1997-11-05 Becton Dickinson Co One step test for absolute counts
FR2672128B1 (fr) * 1991-01-28 1995-08-18 Cis Bio Int Procede de mesure de la luminescence emise dans un dosage par luminescence.
US6352672B1 (en) 1991-01-28 2002-03-05 Cis Bio International Apparatus for measuring the luminescence emitted in a luminescent assay
US5776709A (en) * 1991-08-28 1998-07-07 Becton Dickinson And Company Method for preparation and analysis of leukocytes in whole blood
CA2087086A1 (en) 1992-01-22 1993-07-23 Leon Wmm Terstappen Multidimensional cell differential analysis
US6861264B2 (en) * 1992-01-27 2005-03-01 Cis Bio International Method of measuring the luminescence emitted in a luminescent assay
ES2151494T3 (es) * 1992-03-05 2001-01-01 Becton Dickinson Co Metodo para la preparacion y analisis de leucocitos en sangre completa mediante la utilizacion de citometria de flujo.
IL102645A (en) * 1992-07-26 1998-02-22 Yeda Res & Dev Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them
EP0586183B1 (de) * 1992-09-04 1999-10-13 Becton, Dickinson and Company Kontroll-Teilchen für die Zellzählung und Instrumentenlinearität
US6008373A (en) 1995-06-07 1999-12-28 Carnegie Mellon University Fluorescent labeling complexes with large stokes shift formed by coupling together cyanine and other fluorochromes capable of resonance energy transfer
WO1998005944A1 (en) * 1996-08-02 1998-02-12 The Regents Of The University Of California Phytofluors as fluorescent labels
US6544797B1 (en) 1997-04-09 2003-04-08 Biosite Diagnostics, Inc. Compositions and methods for inhibiting light-induced inactivation of biological reagents
US7745142B2 (en) 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US7632651B2 (en) 1997-09-15 2009-12-15 Mds Analytical Technologies (Us) Inc. Molecular modification assays
US7070921B2 (en) 2000-04-28 2006-07-04 Molecular Devices Corporation Molecular modification assays
US6133429A (en) * 1997-10-03 2000-10-17 Becton Dickinson And Company Chromophores useful for the preparation of novel tandem conjugates
US6821740B2 (en) * 1998-02-25 2004-11-23 Becton, Dickinson And Company Flow cytometric methods for the concurrent detection of discrete functional conformations of PRB in single cells
US6200766B1 (en) 1998-12-03 2001-03-13 Becton Dickinson And Company Methods and reagents for quantitation of HLA-DR expression on peripheral blood cells
US6423505B1 (en) 1998-12-03 2002-07-23 Becton Dickinson And Company Methods and reagents for quantitation of HLA-DR and CD11b expression on peripheral blood cells
US6197520B1 (en) * 1999-08-13 2001-03-06 University Of Utah Research Foundation Solution-based color compensation adjusted for temperature and electronic gains
WO2001027625A1 (en) 1999-10-08 2001-04-19 Leif Robert C Conjugated polymer tag complexes
CA2454515A1 (en) * 2001-07-25 2003-02-06 Mitsubishi Pharma Corporation Cancer diagnostics
US20040248128A1 (en) * 2001-08-27 2004-12-09 Sakura Sakano Method of analyzing interaction between material and biological substance
WO2006081620A1 (en) * 2005-02-02 2006-08-10 Newsouth Innovations Pty Limited Cd4+ cd25+ t-cells activated to a specific antigen
DK2441461T3 (da) 2005-11-07 2014-07-28 Amorcyte Inc Sammensætninger og fremgangsmåder til reparation af vaskulær skade
US8569059B2 (en) 2006-08-02 2013-10-29 Newsouth Innovations Pty Limited Method of identifying CD4+ CD25+ T-cells activated to an antigen which express CD8
EP2361930A3 (de) 2007-03-26 2011-10-26 Dako Denmark A/S Multimere von peptide-mhc komplexen und deren verwendung in borrelia infektionskrankheiten
EP2167536A1 (de) * 2007-07-03 2010-03-31 Dako Denmark A/S Mhc-multimere, verfahren zu ihrer herstellung, markierung und verwendung
US7816135B2 (en) 2007-07-05 2010-10-19 Becton, Dickinson And Company Method of analyzing lymphocytes
US10611818B2 (en) 2007-09-27 2020-04-07 Agilent Technologies, Inc. MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
US10968269B1 (en) 2008-02-28 2021-04-06 Agilent Technologies, Inc. MHC multimers in borrelia diagnostics and disease
US10722562B2 (en) 2008-07-23 2020-07-28 Immudex Aps Combinatorial analysis and repair
GB0817244D0 (en) * 2008-09-20 2008-10-29 Univ Cardiff Use of a protein kinase inhibitor to detect immune cells, such as T cells
US11992518B2 (en) 2008-10-02 2024-05-28 Agilent Technologies, Inc. Molecular vaccines for infectious disease
US10369204B2 (en) 2008-10-02 2019-08-06 Dako Denmark A/S Molecular vaccines for infectious disease
US8153442B2 (en) * 2009-10-21 2012-04-10 Siemens Healthcare Diagnostics Inc. Stabilization of signal generation in particles used in assays
EP2491114B8 (de) 2009-10-23 2017-01-25 Amorcyte, Inc. Zusammensetzungen und verwendungen zur behandlung fortschreitender myokardialverletzungen aufgrund von gefässinsuffizienz
US9533010B2 (en) 2011-10-31 2017-01-03 Amorcyte, Llc Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency
GB201205288D0 (en) * 2012-03-26 2012-05-09 Protein Technologies Ltd Peridinin-chlorophyll binding proteins
JP7222884B2 (ja) 2016-08-29 2023-02-15 ハッケンサック ユニヴァーシティ メディカル センター Ｔ細胞区画において自己反応性を低下させることにより免疫障害関連疾患を治療する方法
BR112018016717A2 (pt) 2016-12-16 2018-12-26 H Lundbeck As agentes, usos e métodos
CA3071287A1 (en) 2017-08-31 2019-03-07 Agilent Technologies, Inc. Composition for stabilization of antibody formulations containing percp
US20200309796A1 (en) 2017-12-21 2020-10-01 H. Lundbeck A/S Assay, method and treatment of alpha-synucleinopathies
CN114563362B (zh) * 2022-01-29 2022-11-04 大连海事大学 一种船舶压载水微藻含量的检测方法

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JPS5371898A (en) * 1976-12-07 1978-06-26 Kuraray Co Quantitative analysis of immune substance
US4238195A (en) * 1979-01-18 1980-12-09 Miles Laboratories, Inc. Fluorescer-labeled specific binding assays
CA1186621A (en) * 1981-08-10 1985-05-07 John L. Hendrix Fluoro immuno assay system
DE3262442D1 (en) * 1981-10-06 1985-03-28 Univ Leland Stanford Junior Fluorescent conjugates for analysis of molecules and cells
US4542104A (en) * 1983-04-06 1985-09-17 The Board Of Trustees Of The Leland Stanford Jr. Univ. Phycobiliprotein fluorescent conjugates
DE3464252D1 (en) * 1983-06-03 1987-07-23 Hoffmann La Roche Labelled molecules for fluorescence immunoassays and processes and intermediates for their preparation
US4745285A (en) * 1986-08-21 1988-05-17 Becton Dickinson And Company Multi-color fluorescence analysis with single wavelength excitation

Also Published As

Publication number Publication date
ES2059533T3 (es) 1994-11-16
EP0314406B1 (de) 1993-08-25
US4876190A (en) 1989-10-24
EP0314406A1 (de) 1989-05-03
JPH01147368A (ja) 1989-06-09
DE3883478T2 (de) 1994-02-17
JPH0614043B2 (ja) 1994-02-23
ATE93628T1 (de) 1993-09-15

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Legal Events

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