DE3880691D1 - Zusammensetzung und verfahren zur anwendung von in liposomen eingeschlossenen verbindungen in der neutroneneinfangtherapie von tumoren. - Google Patents

Zusammensetzung und verfahren zur anwendung von in liposomen eingeschlossenen verbindungen in der neutroneneinfangtherapie von tumoren.

Info

Publication number
DE3880691D1
DE3880691D1 DE8989900703T DE3880691T DE3880691D1 DE 3880691 D1 DE3880691 D1 DE 3880691D1 DE 8989900703 T DE8989900703 T DE 8989900703T DE 3880691 T DE3880691 T DE 3880691T DE 3880691 D1 DE3880691 D1 DE 3880691D1
Authority
DE
Germany
Prior art keywords
neutron capture
capture therapy
tumor
composition
enclosed components
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8989900703T
Other languages
English (en)
Other versions
DE3880691T2 (de
Inventor
Gary Fujii
Paul Schmidt
Ronald Gamble
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nexstar Pharmaceuticals Inc
Original Assignee
Vestar Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vestar Inc filed Critical Vestar Inc
Application granted granted Critical
Publication of DE3880691D1 publication Critical patent/DE3880691D1/de
Publication of DE3880691T2 publication Critical patent/DE3880691T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009—Neutron capture therapy, e.g. using uranium or non-boron material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009—Neutron capture therapy, e.g. using uranium or non-boron material
    • A61K41/0095—Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A61K51/1234—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE8989900703T 1987-11-04 1988-11-03 Zusammensetzung und verfahren zur anwendung von in liposomen eingeschlossenen verbindungen in der neutroneneinfangtherapie von tumoren. Expired - Lifetime DE3880691T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11676487A 1987-11-04 1987-11-04
PCT/US1988/003820 WO1989004176A1 (en) 1987-11-04 1988-11-03 Composition and method of use for liposome encapsulated compounds for neutron capture tumor therapy

Publications (2)

Publication Number Publication Date
DE3880691D1 true DE3880691D1 (de) 1993-06-03
DE3880691T2 DE3880691T2 (de) 1993-08-12

Family

ID=22369060

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989900703T Expired - Lifetime DE3880691T2 (de) 1987-11-04 1988-11-03 Zusammensetzung und verfahren zur anwendung von in liposomen eingeschlossenen verbindungen in der neutroneneinfangtherapie von tumoren.

Country Status (8)

Country Link
EP (1) EP0386146B1 (de)
JP (1) JP2710847B2 (de)
KR (1) KR970009893B1 (de)
AT (1) ATE88642T1 (de)
AU (1) AU2820689A (de)
CA (1) CA1314209C (de)
DE (1) DE3880691T2 (de)
WO (1) WO1989004176A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648532A (en) * 1993-06-03 1997-07-15 The Regents Of The University Of California Compositions for boron neutron capture therapy and methods thereof
NO312708B1 (no) * 2000-02-21 2002-06-24 Anticancer Therapeutic Inv Sa Radioaktive liposomer til terapi
US20040170677A1 (en) * 2002-11-26 2004-09-02 Ning Hu Method of drug loading in liposomes by gradient
CA2768444A1 (en) 2009-07-17 2011-01-20 Rigshospitalet Loading technique for preparing radionuclide and ionophore containing liposomes in which the ionophore is 2-hydroxyquionoline (carbostyril) or structurally related 2-hydroxyquinolines
AU2011344865B2 (en) 2010-12-14 2017-03-09 Rigshospitalet Entrapment of radionuclides in nanoparticle compositions
WO2024044621A1 (en) * 2022-08-23 2024-02-29 San Jose State University Research Foundation Boronated nanoscale substrate and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992513A (en) * 1975-01-07 1976-11-16 Atomic Energy Of Canada Limited Labelled phospholipid material colloidially dispersed and sized to localize at preselected organs
US4516535A (en) 1982-06-22 1985-05-14 Nuclear Medicine, Inc. Methods for neutron-capture tumor therapy
US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
US4674480A (en) * 1984-05-25 1987-06-23 Lemelson Jerome H Drug compositions and methods of applying same

Also Published As

Publication number Publication date
KR890701134A (ko) 1989-12-19
EP0386146A1 (de) 1990-09-12
DE3880691T2 (de) 1993-08-12
JP2710847B2 (ja) 1998-02-10
KR970009893B1 (en) 1997-06-19
EP0386146B1 (de) 1993-04-28
ATE88642T1 (de) 1993-05-15
EP0386146A4 (en) 1990-10-24
AU2820689A (en) 1989-06-01
CA1314209C (en) 1993-03-09
JPH03500888A (ja) 1991-02-28
WO1989004176A1 (en) 1989-05-18

Similar Documents

Publication Publication Date Title
Gentry Radioactive halos
Dudley et al. Deposition of radiogallium (Ga72) in proliferating tissues
DE69133325D1 (de) Verwendung von 5,10,15,20-tetrakis(r-carboxyphenyl)porphin zum nachweis und zur behandlung von lungenkrebs
Ingrand Characteristics of radio-isotopes for intra-articular therapy.
ATE238545T1 (de) Verfahren zur identifizierung von chemikalien durch nicht-radioaktive isotope
DE3667353D1 (de) Verfahren und vorrichtung zur bestrahlung von bestrahlungsgut mittels ionisierender strahlung.
SE7404824L (sv) Sett och anordning for metning av koncentrationer av en komponent, ex. vis. jern, i en materialmengd.
DE3880691D1 (de) Zusammensetzung und verfahren zur anwendung von in liposomen eingeschlossenen verbindungen in der neutroneneinfangtherapie von tumoren.
NL7600104A (nl) Dragermateriaal voor plaatsbepaling met radio-ak- tieve isotopen in medisch onderzoek en werkwijze voor de bereiding daarvan.
KR940005295A (ko) 부위- 지향성 치료방법 및 치료수단
DE69024960D1 (de) Verfahren und Gerät zur Herstellung eines radiodiagnostischen gasförmigen Radionukleids
Mays et al. Progress in the beagle studies at the University of Utah
FI924363A0 (fi) Foerfarande foer behandling och/eller diagnostisering av mjukvaevnadstumoerer.
EP0752709A1 (de) Verfahren zur Erzeugung von Actinium-225
RU93003328A (ru) Способ трансмутации изотопов
ATA170284A (de) Verfahren zur intensivierung des trockenmahlens von natuerlichen mineralien und synthetisch hergestellten mineralartigen stoffen
SE7609120L (sv) Analyssett
Lawrence Artificial radio-activity and neutron rays in biology and medicine
GB1365405A (en) Radionuclide generator and method for producing same
Buchtela et al. Electrophoretic separation of carrier-free radionuclides
RU93026033A (ru) Способ маркировки и радиационного контроля объектов
DE3219114A1 (de) Verfahren zur verbesserung der eingenschaften von verfestigungen radioaktiver festabfaelle
GB1512873A (en) Method of separating at least one component of an isotope mixture
Harby Donner Laboratory: Fifty Years of Nuclear Medicine Innovation
GB1240767A (en) Track registration process

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NEXSTAR PHARMACEUTICALS INC. (N.D.GES.D. STAATES D