ATE88642T1 - Zusammensetzung und verfahren zur anwendung von in liposomen eingeschlossenen verbindungen in der neutroneneinfangtherapie von tumoren. - Google Patents

Zusammensetzung und verfahren zur anwendung von in liposomen eingeschlossenen verbindungen in der neutroneneinfangtherapie von tumoren.

Info

Publication number
ATE88642T1
ATE88642T1 AT89900703T AT89900703T ATE88642T1 AT E88642 T1 ATE88642 T1 AT E88642T1 AT 89900703 T AT89900703 T AT 89900703T AT 89900703 T AT89900703 T AT 89900703T AT E88642 T1 ATE88642 T1 AT E88642T1
Authority
AT
Austria
Prior art keywords
compounds
tumors
capture therapy
neutron
entracled
Prior art date
Application number
AT89900703T
Other languages
English (en)
Inventor
Gary Fujii
Paul Gardner Schmidt
Ronald Carl Gamble
Original Assignee
Vestar Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vestar Inc filed Critical Vestar Inc
Application granted granted Critical
Publication of ATE88642T1 publication Critical patent/ATE88642T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009—Neutron capture therapy, e.g. using uranium or non-boron material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009—Neutron capture therapy, e.g. using uranium or non-boron material
    • A61K41/0095—Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A61K51/1234—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT89900703T 1987-11-04 1988-11-03 Zusammensetzung und verfahren zur anwendung von in liposomen eingeschlossenen verbindungen in der neutroneneinfangtherapie von tumoren. ATE88642T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11676487A 1987-11-04 1987-11-04
PCT/US1988/003820 WO1989004176A1 (en) 1987-11-04 1988-11-03 Composition and method of use for liposome encapsulated compounds for neutron capture tumor therapy
EP89900703A EP0386146B1 (de) 1987-11-04 1988-11-03 Zusammensetzung und verfahren zur anwendung von in liposomen eingeschlossenen verbindungen in der neutroneneinfangtherapie von tumoren

Publications (1)

Publication Number Publication Date
ATE88642T1 true ATE88642T1 (de) 1993-05-15

Family

ID=22369060

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89900703T ATE88642T1 (de) 1987-11-04 1988-11-03 Zusammensetzung und verfahren zur anwendung von in liposomen eingeschlossenen verbindungen in der neutroneneinfangtherapie von tumoren.

Country Status (8)

Country Link
EP (1) EP0386146B1 (de)
JP (1) JP2710847B2 (de)
KR (1) KR970009893B1 (de)
AT (1) ATE88642T1 (de)
AU (1) AU2820689A (de)
CA (1) CA1314209C (de)
DE (1) DE3880691T2 (de)
WO (1) WO1989004176A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648532A (en) * 1993-06-03 1997-07-15 The Regents Of The University Of California Compositions for boron neutron capture therapy and methods thereof
NO312708B1 (no) 2000-02-21 2002-06-24 Anticancer Therapeutic Inv Sa Radioaktive liposomer til terapi
EP1599183A2 (de) * 2002-11-26 2005-11-30 Gilead Sciences, Inc. Verfahren zur arzneimittelladung von liposomen durch gradient.
CA2768444A1 (en) 2009-07-17 2011-01-20 Rigshospitalet Loading technique for preparing radionuclide and ionophore containing liposomes in which the ionophore is 2-hydroxyquionoline (carbostyril) or structurally related 2-hydroxyquinolines
WO2012079582A1 (en) 2010-12-14 2012-06-21 Technical University Of Denmark Entrapment of radionuclides in nanoparticle compositions
WO2024044621A1 (en) * 2022-08-23 2024-02-29 San Jose State University Research Foundation Boronated nanoscale substrate and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992513A (en) * 1975-01-07 1976-11-16 Atomic Energy Of Canada Limited Labelled phospholipid material colloidially dispersed and sized to localize at preselected organs
US4516535A (en) 1982-06-22 1985-05-14 Nuclear Medicine, Inc. Methods for neutron-capture tumor therapy
US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
US4674480A (en) * 1984-05-25 1987-06-23 Lemelson Jerome H Drug compositions and methods of applying same

Also Published As

Publication number Publication date
DE3880691T2 (de) 1993-08-12
JP2710847B2 (ja) 1998-02-10
KR890701134A (ko) 1989-12-19
WO1989004176A1 (en) 1989-05-18
JPH03500888A (ja) 1991-02-28
CA1314209C (en) 1993-03-09
KR970009893B1 (en) 1997-06-19
EP0386146A1 (de) 1990-09-12
AU2820689A (en) 1989-06-01
EP0386146B1 (de) 1993-04-28
DE3880691D1 (de) 1993-06-03
EP0386146A4 (en) 1990-10-24

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time