DE3876846T2 - MORPHOLINE DERIVATIVES AND THEIR USE. - Google Patents

MORPHOLINE DERIVATIVES AND THEIR USE.

Info

Publication number
DE3876846T2
DE3876846T2 DE8888302048T DE3876846T DE3876846T2 DE 3876846 T2 DE3876846 T2 DE 3876846T2 DE 8888302048 T DE8888302048 T DE 8888302048T DE 3876846 T DE3876846 T DE 3876846T DE 3876846 T2 DE3876846 T2 DE 3876846T2
Authority
DE
Germany
Prior art keywords
morpholine derivatives
morpholine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888302048T
Other languages
German (de)
Other versions
DE3876846D1 (en
Inventor
Jonathan Robert S Beecham Arch
Norman Harold Rogers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878705587A external-priority patent/GB8705587D0/en
Priority claimed from GB888803261A external-priority patent/GB8803261D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of DE3876846D1 publication Critical patent/DE3876846D1/en
Application granted granted Critical
Publication of DE3876846T2 publication Critical patent/DE3876846T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Fodder In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8888302048T 1987-03-10 1988-03-09 MORPHOLINE DERIVATIVES AND THEIR USE. Expired - Fee Related DE3876846T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878705587A GB8705587D0 (en) 1987-03-10 1987-03-10 Compounds
GB888803261A GB8803261D0 (en) 1988-02-12 1988-02-12 Compounds & treatment

Publications (2)

Publication Number Publication Date
DE3876846D1 DE3876846D1 (en) 1993-02-04
DE3876846T2 true DE3876846T2 (en) 1993-04-29

Family

ID=26291994

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888302048T Expired - Fee Related DE3876846T2 (en) 1987-03-10 1988-03-09 MORPHOLINE DERIVATIVES AND THEIR USE.

Country Status (9)

Country Link
US (2) US4914202A (en)
EP (1) EP0290122B1 (en)
JP (1) JPS646262A (en)
AU (2) AU598644B2 (en)
DE (1) DE3876846T2 (en)
DK (1) DK123788A (en)
HU (1) HU199440B (en)
NZ (1) NZ223812A (en)
PT (1) PT86919B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5281623A (en) * 1990-08-27 1994-01-25 Eli Lilly And Company Method for treating inflammation
CA2264685C (en) 1996-08-27 2002-10-15 Kyoji Noda 2-phenylmorpholin-5-one derivatives and pharmaceutical composition comprising the same
JP2002522499A (en) * 1998-08-12 2002-07-23 スミスクライン・ビーチャム・コーポレイション Calcium decomposing compound
US9784726B2 (en) 2013-01-08 2017-10-10 Atrogi Ab Screening method, a kit, a method of treatment and a compound for use in a method of treatment
WO2018085886A1 (en) * 2016-11-09 2018-05-17 Charles Sturt University Livestock supplement and use thereof
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2832777A (en) * 1956-11-26 1958-04-29 Searle & Co 2-aminophenyl-3-methylmorpholines
US3192208A (en) * 1962-07-31 1965-06-29 Lilly Co Eli Novel substituted morpholines and piperazines and processes for their synthesis
US3256278A (en) * 1963-04-01 1966-06-14 Rexall Drug Chemical N-hydroxy ethyl-ortho acetyl and carbalkoxy amino phenyl-glyoxamides and process formaking 2-orthoamino phenyl-morpholines
US4404222A (en) * 1980-08-25 1983-09-13 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby
EP0049728B1 (en) * 1980-08-25 1986-11-12 American Cyanamid Company Method for enhancing the growth rate of meat-producing animals and for improving the lean meat to fat ratio thereof
DE3476386D1 (en) * 1983-11-02 1989-03-02 Beecham Group Plc MORPHOLINE DERIVATIVES
GB8412862D0 (en) * 1984-05-19 1984-06-27 Beecham Group Plc Compounds
GB8418657D0 (en) * 1984-07-21 1984-08-22 Beecham Group Plc Compounds
ES8800842A1 (en) * 1985-03-01 1987-12-01 Beecham Group Plc Ethanolamine derivatives for administering to livestock.

Also Published As

Publication number Publication date
EP0290122B1 (en) 1992-12-23
HU199440B (en) 1990-02-28
EP0290122A1 (en) 1988-11-09
DE3876846D1 (en) 1993-02-04
HUT49594A (en) 1989-10-30
PT86919A (en) 1988-04-01
US5082840A (en) 1992-01-21
NZ223812A (en) 1991-11-26
JPS646262A (en) 1989-01-10
AU6301990A (en) 1991-01-10
DK123788A (en) 1988-09-11
AU598644B2 (en) 1990-06-28
AU1279788A (en) 1988-09-08
DK123788D0 (en) 1988-03-08
PT86919B (en) 1992-05-29
US4914202A (en) 1990-04-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee