DE3875076D1 - Herstellung von ligand-polymer-konjugat mit einer kontrollierten zahl von eingefuehrten liganden. - Google Patents

Herstellung von ligand-polymer-konjugat mit einer kontrollierten zahl von eingefuehrten liganden.

Info

Publication number
DE3875076D1
DE3875076D1 DE8888118110T DE3875076T DE3875076D1 DE 3875076 D1 DE3875076 D1 DE 3875076D1 DE 8888118110 T DE8888118110 T DE 8888118110T DE 3875076 T DE3875076 T DE 3875076T DE 3875076 D1 DE3875076 D1 DE 3875076D1
Authority
DE
Germany
Prior art keywords
imported
ligands
ligand
production
polymer conjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888118110T
Other languages
English (en)
Other versions
DE3875076T2 (de
Inventor
Lynette A Lewis
Kin Fai Yip
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Inc filed Critical Miles Inc
Application granted granted Critical
Publication of DE3875076D1 publication Critical patent/DE3875076D1/de
Publication of DE3875076T2 publication Critical patent/DE3875076T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DE8888118110T 1987-11-09 1988-10-31 Herstellung von ligand-polymer-konjugat mit einer kontrollierten zahl von eingefuehrten liganden. Expired - Fee Related DE3875076T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/118,566 US4968742A (en) 1987-11-09 1987-11-09 Preparation of ligand-polymer conjugate having a controlled number of introduced ligands

Publications (2)

Publication Number Publication Date
DE3875076D1 true DE3875076D1 (de) 1992-11-05
DE3875076T2 DE3875076T2 (de) 1993-02-18

Family

ID=22379397

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888118110T Expired - Fee Related DE3875076T2 (de) 1987-11-09 1988-10-31 Herstellung von ligand-polymer-konjugat mit einer kontrollierten zahl von eingefuehrten liganden.

Country Status (6)

Country Link
US (1) US4968742A (de)
EP (1) EP0317796B1 (de)
JP (1) JP2607386B2 (de)
AU (1) AU601087B2 (de)
CA (1) CA1305809C (de)
DE (1) DE3875076T2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5585481A (en) * 1987-09-21 1996-12-17 Gen-Probe Incorporated Linking reagents for nucleotide probes
US6031091A (en) * 1987-09-21 2000-02-29 Gen-Probe Incorporated Non-nucleotide linking reagents for nucleotide probes
US5378807A (en) * 1991-08-08 1995-01-03 University Of Massachusetts At Lowell γ-poly(glutamic acid) esters
DE4140142A1 (de) * 1991-12-05 1993-06-09 Boehringer Mannheim Gmbh, 6800 Mannheim, De Multivalentes dextranreagenz zum einsatz in praezipitationstests
GB9200247D0 (en) * 1992-01-07 1992-02-26 Erba Carlo Spa Pharmaceutical compositions containing polymer derivative-bound anthracycline glycosides and a method for their preparation
DE4211351A1 (de) * 1992-04-04 1993-10-07 Behringwerke Ag Verfahren zur Analyse partikelverstärkter Agglutinationsreaktionen auf Zentrifugalanalysatoren durch Bestimmung der Trübungsaufhellung
US5447846A (en) * 1992-07-17 1995-09-05 Fuji Photo Film C., Ltd. Homogeneous Immunoassay process using covalent conjugate of enzyme and plural monoclonal antibodies for different epitopes on analyte
US5440023A (en) * 1992-09-18 1995-08-08 Beckman Instruments, Inc. Method for making valproic acid derivatives
EP0593956B1 (de) * 1992-10-21 2002-02-13 Dade Behring Inc. Agglutinationstest unter Anwendung eines multivalenten Liganden
JP3607289B2 (ja) * 1993-03-29 2005-01-05 ミネソタ マイニング アンド マニュファクチャリング カンパニー 多孔質支持体（ｐ．ｅ．アズラクトン）の内部にリガンドをカップリングする方法及びその使用法
US5449720A (en) * 1993-05-24 1995-09-12 Biotech Australia Pty Limited Amplification of the VB12 uptake system using polymers
US5561097A (en) * 1994-04-28 1996-10-01 Minnesota Mining And Manufacturing Company Method of controlling density of ligand coupled onto supports and products produced therefrom
JP3715027B2 (ja) 1996-05-07 2005-11-09 シスメックス株式会社 Ｃ型肝炎ウイルス感染症診断薬
US7459127B2 (en) 2002-02-26 2008-12-02 Siemens Healthcare Diagnostics Inc. Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces
US7094354B2 (en) 2002-12-19 2006-08-22 Bayer Healthcare Llc Method and apparatus for separation of particles in a microfluidic device
US7125711B2 (en) 2002-12-19 2006-10-24 Bayer Healthcare Llc Method and apparatus for splitting of specimens into multiple channels of a microfluidic device
US7347617B2 (en) 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
JP4581571B2 (ja) * 2004-09-06 2010-11-17 富士ゼロックス株式会社 粒子のマレイミジル基量を測定する定量方法
US7421348B2 (en) * 2005-03-18 2008-09-02 Swanson Brian G Predictive emissions monitoring method
US8574913B2 (en) * 2007-10-30 2013-11-05 Panasonic Corporation Method for measurement of hemoglobin and hemoglobin derivative, and measurement kit
JP5563470B2 (ja) * 2007-11-20 2014-07-30 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッド 糖化ヘモグロビン検出法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2402664A1 (fr) * 1977-09-07 1979-04-06 Agronomique Inst Nat Rech Produits de couplage phosphorylcholine, composes amines procede d'obtention et applications
AU533026B2 (en) * 1979-10-26 1983-10-27 Dynasciences Corp. Passively adsorbing immuno-reactive haptens to solid phases
DE3224788A1 (de) * 1981-07-17 1983-02-03 South African Inventions Development Corp., Scientia, Pretoria,Transvaal Traegergebundenes immunogenes material
US4434150A (en) * 1981-10-19 1984-02-28 Ortho Diagnostic Systems, Inc. Immunological reagents employing polymeric backbone possessing reactive functional groups
JPS58209994A (ja) * 1982-05-10 1983-12-07 Fujirebio Inc 活性蛋白等固定化物を用いた抗原の測定方法
US4711840A (en) * 1984-01-27 1987-12-08 Genetic Systems Corporation Polymerization-induced separation immunoassays
US4752638A (en) * 1983-11-10 1988-06-21 Genetic Systems Corporation Synthesis and use of polymers containing integral binding-pair members
DE3486275T2 (de) * 1983-11-10 1994-09-08 Genetic Systems Corp Integralantikörper enthaltende polymerisierbare Verbindungen und deren Anwendungen in Immuntesten mit durch Polymerisation induzierter Trennung.
FR2557458B1 (fr) * 1983-12-30 1987-09-04 Centre Nat Rech Scient Nouveaux anticorps capables de reconnaitre specifiquement des groupements hapteniques, leur preparation et leur application, et nouveaux antigenes permettant de les preparer
GB8423228D0 (en) * 1984-09-14 1984-10-17 Unilever Plc Specific binding materials
DE3613111A1 (de) * 1986-04-18 1987-10-22 Behringwerke Ag Dispersionspolymere, verfahren zu ihrer herstellung und ihre verwendung
EP0251527A3 (de) * 1986-06-13 1990-01-24 Panab Laboratories, Inc. Haptenylierte Reagenzien und Immunotests

Also Published As

Publication number Publication date
DE3875076T2 (de) 1993-02-18
AU2465788A (en) 1989-06-01
AU601087B2 (en) 1990-08-30
EP0317796A1 (de) 1989-05-31
JP2607386B2 (ja) 1997-05-07
EP0317796B1 (de) 1992-09-30
CA1305809C (en) 1992-07-28
JPH01155272A (ja) 1989-06-19
US4968742A (en) 1990-11-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee