DE3866303D1 - Verfahren zum loesen von argininamiden und sie enthaltende pharmazeutische mittel. - Google Patents

Verfahren zum loesen von argininamiden und sie enthaltende pharmazeutische mittel.

Info

Publication number
DE3866303D1
DE3866303D1 DE8888401968T DE3866303T DE3866303D1 DE 3866303 D1 DE3866303 D1 DE 3866303D1 DE 8888401968 T DE8888401968 T DE 8888401968T DE 3866303 T DE3866303 T DE 3866303T DE 3866303 D1 DE3866303 D1 DE 3866303D1
Authority
DE
Germany
Prior art keywords
solving
same
pharmaceutical agents
agents containing
arginine amides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8888401968T
Other languages
English (en)
Inventor
Kunihiko - Mitsubishi-K Ofuchi
Tatsuo - Mitsubishi-Kas Nomura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Chemical Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Application granted granted Critical
Publication of DE3866303D1 publication Critical patent/DE3866303D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
DE8888401968T 1987-07-28 1988-07-28 Verfahren zum loesen von argininamiden und sie enthaltende pharmazeutische mittel. Expired - Lifetime DE3866303D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62188484A JPS6431727A (en) 1987-07-28 1987-07-28 Dissolution of argininamide and drug composition containing argininamides

Publications (1)

Publication Number Publication Date
DE3866303D1 true DE3866303D1 (de) 1992-01-02

Family

ID=16224539

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8888401968T Expired - Lifetime DE3866303D1 (de) 1987-07-28 1988-07-28 Verfahren zum loesen von argininamiden und sie enthaltende pharmazeutische mittel.
DE122005000056C Active DE122005000056I2 (de) 1987-07-28 1988-07-28 Verfahren zum Lösen von Argininamiden und sie enthaltende pharmazeutische Mittel.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE122005000056C Active DE122005000056I2 (de) 1987-07-28 1988-07-28 Verfahren zum Lösen von Argininamiden und sie enthaltende pharmazeutische Mittel.

Country Status (3)

Country Link
EP (1) EP0301970B1 (de)
JP (1) JPS6431727A (de)
DE (2) DE3866303D1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2053057T3 (es) * 1990-04-03 1994-07-16 Friedrich Geb Elemento de proteccion para las superficies de hermeticidad en la construccion de vertederos y procedimiento para elaborar una capa protectora.
JPH06219948A (ja) * 1993-01-25 1994-08-09 Mitsubishi Kasei Corp 抗トロンビン剤及びその製造方法
JPH06219949A (ja) * 1993-01-25 1994-08-09 Mitsubishi Kasei Corp 抗トロンビン剤及びその製造方法
ATE177635T1 (de) * 1993-04-22 1999-04-15 Senju Pharma Co Wässrige arzneizubereitungen enthaltend argatroban und cyclodextrin oder coffein
FR2715566B1 (fr) * 1994-02-03 1996-03-08 Synthelabo Solutions aqueuses concentrées d'argatroban.
JP2006008696A (ja) * 2003-03-20 2006-01-12 Mitsubishi Pharma Corp アルギニンアミド類を含有する医薬製剤
JP3781308B2 (ja) * 2003-03-20 2006-05-31 三菱ウェルファーマ株式会社 アルギニンアミド類を含有する医薬製剤
US7915290B2 (en) 2008-02-29 2011-03-29 Baxter International Inc. Argatroban formulations and methods for making and using same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2854380A (en) * 1955-09-06 1958-09-30 Upjohn Co Aqueous therapeutic composition comprising reserpine, propylene glycol and sorbitol
US4258192A (en) * 1977-12-16 1981-03-24 Mitsubishi Chemical Industries Limited N2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
JPS5692213A (en) * 1979-12-25 1981-07-25 Mitsubishi Chem Ind Ltd Anticoagulant comprising n2-arylsulfonyl-l-arginine amide or its salt as active ingredient
JPS5782314A (en) * 1980-11-13 1982-05-22 Mitsubishi Chem Ind Ltd Carcinostatic agent

Also Published As

Publication number Publication date
JPH0576929B2 (de) 1993-10-25
JPS6431727A (en) 1989-02-02
DE122005000056I2 (de) 2008-10-02
EP0301970B1 (de) 1991-11-21
EP0301970A1 (de) 1989-02-01
DE122005000056I1 (de) 2006-02-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MITSUBISHI CHEMICAL CORP., TOKIO/TOKYO, JP

V448 Application of spc

Free format text: PRODUCT NAME: ARGATROBAN ODER EIN SALZ HIERVON; REGISTRATION NO/DATE: 62085.00.00, 20050601

Spc suppl protection certif: 12 2005 000 056

Filing date: 20051122

Free format text: PRODUCT NAME: ARGATROBAN; REGISTRATION NO/DATE: 62085.00.00, 20050601

Spc suppl protection certif: 12 2005 000 056

Filing date: 20051122

V484 Delivery of the decision of grant

Free format text: PRODUCT NAME: ARGATROBAN; REGISTRATION NO/DATE: 62085.00.00, 20050601

Spc suppl protection certif: 12 2005 000 056

Filing date: 20051122

V457 Spc granted

Free format text: PRODUCT NAME: ARGATROBAN; REGISTRATION NO/DATE: 62085.00.00, 20050601

Spc suppl protection certif: 12 2005 000 056

Filing date: 20051122

R071 Expiry of right

Free format text: PRODUCT NAME: ARGATROBAN ODER EIN SALZ HIERVON; NAT. REGISTRATION NO/DATE: 62085.00.00 20050601; FIRST REGISTRATION: SE 19239 20041015

Spc suppl protection certif: 122005000056

Filing date: 20051122

Expiry date: 20080729

Extension date: 20130728

R071 Expiry of right

Free format text: PRODUCT NAME: ARGATROBAN ODER EIN SALZ HIERVON; NAT. REGISTRATION NO/DATE: 62085.00.00 20050601; FIRST REGISTRATION: SE 19239 20041015

Spc suppl protection certif: 122005000056

Filing date: 20051122

Expiry date: 20080729

Extension date: 20130728

Effective date: 20130729