DE3853535D1 - Ärztliche antimikrobielle polypeptide, deren verwendung und verfahren zur herstellung. - Google Patents

Ärztliche antimikrobielle polypeptide, deren verwendung und verfahren zur herstellung.

Info

Publication number
DE3853535D1
DE3853535D1 DE3853535T DE3853535T DE3853535D1 DE 3853535 D1 DE3853535 D1 DE 3853535D1 DE 3853535 T DE3853535 T DE 3853535T DE 3853535 T DE3853535 T DE 3853535T DE 3853535 D1 DE3853535 D1 DE 3853535D1
Authority
DE
Germany
Prior art keywords
phage
antimicrobial agents
cells
protein
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3853535T
Other languages
English (en)
Other versions
DE3853535T2 (de
Inventor
Jesse Jaynes
Frederick M Enright
Kenneth White
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helix Biomedix Inc
Original Assignee
Louisiana State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Louisiana State University filed Critical Louisiana State University
Application granted granted Critical
Publication of DE3853535D1 publication Critical patent/DE3853535D1/de
Publication of DE3853535T2 publication Critical patent/DE3853535T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06Lysis of microorganisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Insects & Arthropods (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Enzymes And Modification Thereof (AREA)
DE3853535T 1987-07-06 1988-07-06 Ärztliche antimikrobielle polypeptide, deren verwendung und verfahren zur herstellung. Expired - Lifetime DE3853535T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6965387A 1987-07-06 1987-07-06
PCT/US1988/002265 WO1989000199A1 (en) 1987-07-06 1988-07-06 Therapeutic antimicrobial polypeptides, their use and methods for preparation

Publications (2)

Publication Number Publication Date
DE3853535D1 true DE3853535D1 (de) 1995-05-11
DE3853535T2 DE3853535T2 (de) 1995-10-12

Family

ID=22090376

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3853535T Expired - Lifetime DE3853535T2 (de) 1987-07-06 1988-07-06 Ärztliche antimikrobielle polypeptide, deren verwendung und verfahren zur herstellung.

Country Status (8)

Country Link
US (1) US6303568B1 (de)
EP (1) EP0365598B1 (de)
KR (1) KR970005048B1 (de)
AT (1) ATE120795T1 (de)
AU (1) AU2071488A (de)
CA (1) CA1327311C (de)
DE (1) DE3853535T2 (de)
WO (1) WO1989000199A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110754400A (zh) * 2019-10-28 2020-02-07 长江大学 一种提高黄鳝苗种人工孵化率的方法

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US5861478A (en) 1987-07-06 1999-01-19 Helix Biomedix, Inc. Lytic peptides
WO1989000194A1 (en) * 1987-07-06 1989-01-12 Louisiana State University Agricultural And Mechan Inhibition of eucaryotic pathogens and neoplasms and stimulation of fibroblasts and lymphocytes with lytic peptides
US5968904A (en) * 1993-06-04 1999-10-19 Demegen, Inc. Modified arginine containing lytic peptides and method of making the same by glyoxylation
WO1995001424A1 (en) * 1993-06-30 1995-01-12 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Transformed mammalian cells capable of expressing cecropin b
AU7321294A (en) * 1993-06-30 1995-01-24 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College, The Transformed eukaryotic cells, and transposon-based transformation vectors
US6156568A (en) * 1993-06-30 2000-12-05 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Transformed eukaryotic cells
US5856178A (en) * 1993-08-30 1999-01-05 Utah State University DNA cassettes for expression of lytic peptides in mammalian cells and transgenic organisms containing same
US5998698A (en) * 1995-06-07 1999-12-07 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Transgenic fish capable of expressing exogenous lytic peptides
US6288212B1 (en) 1998-08-28 2001-09-11 The University Of British Columbia Anti-endotoxic, antimicrobial cationic peptides and methods of use therefor
AU774841B2 (en) * 1998-12-03 2004-07-08 Targanta Therapeutics Inc. Development of novel anti-microbial agents based on bacteriophage genomics
US6982153B1 (en) 1998-12-03 2006-01-03 Targanta Therapeutics, Inc. DNA sequences from staphylococcus aureus bacteriophage 77 that encode anti-microbial polypeptides
US6753407B2 (en) 2000-08-15 2004-06-22 North Carolina State University Antimicrobial peptides isolated from fish
AU2001287179A1 (en) * 2000-08-15 2002-02-25 North Carolina State University Antimicrobial peptides isolated from fish
JP2004515251A (ja) 2000-12-19 2004-05-27 ファゲテック,インコーポレイティド スタフィロコッカス・アウレウス必須遺伝子及びそのコードされるタンパク質staau_r9に関連する組成物及び方法
US20080124787A1 (en) * 2001-02-13 2008-05-29 Avigenics, Inc. Microinjection devices and methods of use
US6875744B2 (en) * 2001-03-28 2005-04-05 Helix Biomedix, Inc. Short bioactive peptides
KR100891157B1 (ko) * 2001-03-28 2009-04-07 헬릭스 바이오메딕스, 인코포레이티드 짧은 생물활성 펩티드 및 그것들의 사용 방법
US20050209157A1 (en) * 2001-03-28 2005-09-22 Owen Donald R Short bioactive peptides and methods for their use
WO2003089455A2 (en) * 2002-04-22 2003-10-30 Dow Global Technologies Inc. Low-cost production of peptides
US20040172667A1 (en) 2002-06-26 2004-09-02 Cooper Richard K. Administration of transposon-based vectors to reproductive organs
US20040235011A1 (en) * 2002-06-26 2004-11-25 Cooper Richard K. Production of multimeric proteins
US7527966B2 (en) 2002-06-26 2009-05-05 Transgenrx, Inc. Gene regulation in transgenic animals using a transposon-based vector
WO2004072251A2 (en) * 2003-02-07 2004-08-26 Wisconsin Alumni Research Foundation Directed genetic modifications of human stem cells
WO2005062881A2 (en) 2003-12-24 2005-07-14 Transgenrx, Inc. Gene therapy using transposon-based vectors
WO2005090385A2 (en) * 2004-03-18 2005-09-29 Ansata Therapeutics, Inc. Compositions having antimicrobial activity and uses thereof
CA2597191C (en) * 2005-02-09 2014-04-01 Helix Biomedix Inc. Antimicrobial hexapeptides
US20070129690A1 (en) 2005-12-02 2007-06-07 Joel Rosenblatt Catheter with polymeric coating
US20080188830A1 (en) * 2007-02-06 2008-08-07 Arrow International, Inc. Selectively reinforced medical devices
US20090175967A1 (en) * 2008-01-04 2009-07-09 Nutracea Methods for treatment of intestinal carcinogenesis with rice bran
KR101749310B1 (ko) * 2008-01-24 2017-06-21 에스퍼란스 파마슈티컬스, 인코포레이티드 용해 도메인 융합 구성물 및 이를 제조하고 사용하는 방법
US9157097B2 (en) 2008-09-25 2015-10-13 Proteovec Holding, L.L.C. Vectors for production of growth hormone
US9150880B2 (en) 2008-09-25 2015-10-06 Proteovec Holding, L.L.C. Vectors for production of antibodies
WO2010039828A1 (en) * 2008-10-01 2010-04-08 Teleflex Medical Incorporated Article containing segregated biguanide and lewis acid
WO2010118360A1 (en) 2009-04-09 2010-10-14 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Production of proteins using transposon-based vectors
DK2914633T3 (da) 2012-10-30 2022-03-14 Esperance Pharmaceuticals Inc Antistof/lægemiddel-konjugater og anvendelsesfremgangsmåder

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FR489987A (fr) 1917-07-04 1919-03-26 Otis Pifre Ateliers Sa Perfectionnement apporté aux tours et machines similaires
GB140556A (en) 1919-04-09 1920-04-01 Sidney George Palmer Improvements in and relating to the construction of buildings
FR7869M (de) * 1967-11-03 1970-04-27
US3911110A (en) 1972-12-22 1975-10-07 Canadian Patents Dev Insecticidal compositions
US4704362A (en) 1977-11-08 1987-11-03 Genentech, Inc. Recombinant cloning vehicle microbial polypeptide expression
US4355104A (en) * 1980-06-17 1982-10-19 Kabigen Ab Bacteriolytic proteins
US4520016A (en) * 1980-06-17 1985-05-28 Kabigen Ab Bacteriolytic proteins
DE3023787A1 (de) * 1980-06-25 1982-01-21 Studiengesellschaft Kohle mbH, 4330 Mülheim Verfahren zur erhoehung der inkorporation und der expression von genetischem material in die kerne von intakten zellen mit hilfe von liposomen
JPH0795953B2 (ja) 1981-04-27 1995-10-18 ワシントン・リサ−チ・ファンデ−ション 大腸菌中のバシルス・ツリンギエンシス細晶性蛋白質
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US4751081A (en) 1984-03-26 1988-06-14 Advanced Genetic Sciences, Inc. Chitinase-producing bacteria
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US5206154A (en) * 1985-01-28 1993-04-27 Xoma Corporation Method of producing cecropins by microbiological techniques
EP0460709B1 (de) * 1985-01-28 1997-05-21 Xoma Corporation AraB-Promoter und Verfahren zur Herstellung von Polypeptiden einschliesslich Cecropinen mittels mikrobiologischer Verfahren
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110754400A (zh) * 2019-10-28 2020-02-07 长江大学 一种提高黄鳝苗种人工孵化率的方法

Also Published As

Publication number Publication date
WO1989000199A1 (en) 1989-01-12
EP0365598A4 (en) 1991-04-03
US6303568B1 (en) 2001-10-16
EP0365598A1 (de) 1990-05-02
DE3853535T2 (de) 1995-10-12
AU2071488A (en) 1989-01-30
EP0365598B1 (de) 1995-04-05
CA1327311C (en) 1994-03-01
KR890701746A (ko) 1989-12-21
ATE120795T1 (de) 1995-04-15
KR970005048B1 (ko) 1997-04-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: HELIX BIOMEDIX, INC., BATON ROUGE, LA., US

8327 Change in the person/name/address of the patent owner

Owner name: HELIX BIOMEDIX, INC., BOTHELL, WASH., US