DE3853320D1 - Fluorophore für die Abkapselung in Liposome. - Google Patents

Fluorophore für die Abkapselung in Liposome.

Info

Publication number
DE3853320D1
DE3853320D1 DE3853320T DE3853320T DE3853320D1 DE 3853320 D1 DE3853320 D1 DE 3853320D1 DE 3853320 T DE3853320 T DE 3853320T DE 3853320 T DE3853320 T DE 3853320T DE 3853320 D1 DE3853320 D1 DE 3853320D1
Authority
DE
Germany
Prior art keywords
compounds
fluorescein
metal
fluorescence
fluorophores
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3853320T
Other languages
English (en)
Other versions
DE3853320T2 (de
Inventor
Michael D Fiechtner
Christopher Bieniarz
Mohamed Shipchandler
Maciej Adamczyk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE3853320D1 publication Critical patent/DE3853320D1/de
Publication of DE3853320T2 publication Critical patent/DE3853320T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/5432—Liposomes or microcapsules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/586—Liposomes, microcapsules or cells

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Nanotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE3853320T 1987-06-29 1988-06-01 Fluorophore für die Abkapselung in Liposome. Expired - Fee Related DE3853320T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/067,833 US4912208A (en) 1987-06-29 1987-06-29 Fluorophores for encapsulation into liposomes

Publications (2)

Publication Number Publication Date
DE3853320D1 true DE3853320D1 (de) 1995-04-20
DE3853320T2 DE3853320T2 (de) 1995-10-19

Family

ID=22078712

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3853320T Expired - Fee Related DE3853320T2 (de) 1987-06-29 1988-06-01 Fluorophore für die Abkapselung in Liposome.

Country Status (8)

Country Link
US (1) US4912208A (de)
EP (1) EP0297303B1 (de)
JP (1) JPS6422878A (de)
AT (1) ATE119904T1 (de)
AU (1) AU598385B2 (de)
CA (1) CA1295999C (de)
DE (1) DE3853320T2 (de)
ES (1) ES2072253T3 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130446A (en) * 1985-06-25 1992-07-14 Siska Diagnostics, Inc. Fluorescent compounds for tagging nucleic acid probes
NO884565L (no) * 1987-10-15 1989-04-17 Univ Moskovsk Preparat for kontrastdannelse ved diagnose av ondartet neoplasma.
US5375606A (en) * 1990-02-28 1994-12-27 Zynaxis, Inc. Bio-analytical separation method
ATE155893T1 (de) * 1990-05-16 1997-08-15 Abbott Lab Test für barbiturate, tracer, immunogene, antikörper und testsatz dafür
US5272260A (en) * 1992-01-29 1993-12-21 Abbott Laboratories Reagents and methods for the determination of glycohydrolytic enzymes
ES2198823T3 (es) * 1992-03-30 2004-02-01 Abbott Laboratories Reactivos que permiten la deteccion y la cuantificacion de la tiroxina en muestras de fluido.
US5352803A (en) * 1992-03-30 1994-10-04 Abbott Laboratories 5(6)-methyl substituted fluorescein derivatives
EP1792897B1 (de) 1993-06-30 2009-09-16 Abbott Laboratories Interkalatoren mit DNA-Affinität und Anwendungsverfahren
IT1298693B1 (it) * 1996-04-24 2000-01-12 Hoffmann La Roche Derivati della fluoresceina 4'-metil sostituiti
TWI239847B (en) * 1997-12-02 2005-09-21 Elan Pharm Inc N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
WO2002004562A2 (en) * 2000-07-07 2002-01-17 Massachussets Institute Of Technology Fluorescein-based metal sensors, and methods of making and using the same
US20040110828A1 (en) * 2002-11-27 2004-06-10 Chowdhury Dipak K. Tetrahydrocannabinol compositions and methods of manufacture and use thereof
US7399639B2 (en) 2003-05-04 2008-07-15 Massachusetts Institute Of Technology Sensors, and methods of making and using the same
US7615377B2 (en) 2003-09-05 2009-11-10 Massachusetts Institute Of Technology Fluorescein-based metal sensors
US20080113014A1 (en) * 2004-01-28 2008-05-15 Ltt Bio-Pharma Co., Ltd. Method for Screening for Compounds Safe for Gastric Mucosa
GB0811385D0 (en) * 2008-06-20 2008-07-30 Artemis Intelligent Power Ltd Fluid working machines and method
KR101933622B1 (ko) * 2012-10-09 2018-12-28 삼성전자주식회사 소포를 모니터링하기 위한 조성물, 키트 및 이를 이용하여 소포를 모니터링하는 방법

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4130634A (en) * 1974-03-15 1978-12-19 University Of Illinois Foundation Method for detecting and quantifying antigens
US4318846A (en) * 1979-09-07 1982-03-09 Syva Company Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers
US4342826A (en) * 1980-02-04 1982-08-03 Collaborative Research, Inc. Immunoassay products and methods
US4304720A (en) * 1980-04-30 1981-12-08 Merck & Co., Inc. Fluorescein esters and ethers and the preparation thereof
US4439356A (en) * 1981-03-03 1984-03-27 Syva Company Unsymmetrical fluorescein derivatives
US4350676A (en) * 1981-05-21 1982-09-21 Laties Alan M Ophthalmic use of carboxyfluorescein
US4668640A (en) * 1981-12-11 1987-05-26 Abbott Laboratories Fluorescence polarization immunoassay utilizing substituted carboxyfluoresceins
US4517303A (en) * 1982-10-20 1985-05-14 E. I. Du Pont De Nemours And Company Specific binding assays utilizing analyte-cytolysin conjugates
US4476229A (en) * 1982-11-08 1984-10-09 Abbott Laboratories Substituted carboxyfluoresceins
US4510251A (en) * 1982-11-08 1985-04-09 Abbott Laboratories Fluorescent polarization assay for ligands using aminomethylfluorescein derivatives as tracers
US4614823A (en) * 1982-11-08 1986-09-30 Abbott Laboratories Aminomethylfluorescein derivatives
EP0201633A3 (de) * 1984-12-20 1989-02-22 Abbott Laboratories Substituierte Anilid-Verbindungen und ihre Verwendung
EP0200960A1 (de) * 1985-05-08 1986-11-12 Abbott Laboratories Fluoreszenzpolarisationsimmunoassay auf Gesamtöstriol
EP0218010A3 (de) * 1985-07-10 1988-01-07 Abbott Laboratories Verfahren zur Bestimmung von Liganden und substituierte Carboxyfluoreszein-Markers zur Durchführung desselben
DE3689688T2 (de) * 1985-10-15 1994-08-25 Abbott Lab Verbindungen und Immunoassay für tricyclische Antidepressiva.
EP0232736A1 (de) * 1986-02-06 1987-08-19 Abbott Laboratories Herstellung von 4'-Aminomethylfluoreszeinderivaten für Fluoreszenzpolarisations-Immunassays

Also Published As

Publication number Publication date
DE3853320T2 (de) 1995-10-19
ES2072253T3 (es) 1995-07-16
JPS6422878A (en) 1989-01-25
AU598385B2 (en) 1990-06-21
CA1295999C (en) 1992-02-18
EP0297303A3 (en) 1989-09-20
US4912208A (en) 1990-03-27
ATE119904T1 (de) 1995-04-15
AU1848288A (en) 1989-01-05
EP0297303A2 (de) 1989-01-04
EP0297303B1 (de) 1995-03-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee