DE381292C - Process for the production of scattering powders - Google Patents
Process for the production of scattering powdersInfo
- Publication number
- DE381292C DE381292C DEF50596D DEF0050596D DE381292C DE 381292 C DE381292 C DE 381292C DE F50596 D DEF50596 D DE F50596D DE F0050596 D DEF0050596 D DE F0050596D DE 381292 C DE381292 C DE 381292C
- Authority
- DE
- Germany
- Prior art keywords
- parts
- scattering
- carbamide
- production
- powders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
Verfahren zur Herstellung von Streupulvern. Streupulver bestehen ganz allgemein aus einer indifferenten Grundlage anorganischer oder organischer Herkunft, wie Talkum, Stärke, Lykopodium u. a., der ein Arzneimittel als wirksames Agens zugesetzt ist. Der Zweck der Grundlage ist, eine feine Verteilung des wirksamen Arzneimittels zu gewährleisten, daneben kommt ihr selbst in manchen Fällen eine aufsaugende und trocknende Wirkung zu. In vielen Fällen ist nun-eine derartige Wirkung nicht erwünscht. Der unlösliche Bestandteil des Streupulvers bleibt namentlich in größeren nässenden Wunden liegen und übt da eine schädliche Reizwirkung aus. Eine einwandfreie lösliche Grundlage für Streupulver war bisher nicht bekannt, da lösliche Stoffe, soweit sie therapeutisch indifferent sind, durch den osmotischen Lösungsdruck meist eine sehr erhebliche Reizwirkung ausüben. Dies ist auch bei dem für Streupulver empfohlenen -Milchzucker der Fall.Process for the production of scattering powders. Scatter powders are whole generally from an indifferent basis of inorganic or organic origin, such as talc, starch, lycopodium and others, to which a medicine is added as an effective agent is. The purpose of the foundation is a fine distribution of the effective drug to ensure that you also come in some cases an absorbent and drying effect too. In many cases, such an effect is not desired. The insoluble constituent of the scattering powder remains in particular in larger, weeping ones Wounds lie and have a harmful irritant effect. A flawless soluble The basis for scattering powder was not previously known, as soluble substances, as far as they are are therapeutically indifferent, mostly very much due to the osmotic pressure of the solution have a considerable irritating effect. This is also recommended for sprinkling powder -Milk sugar the case.
Es wurde nun gefunden, (1a1 staubfein gepulvertes reines- Karbamid eine vorzügliche Grundlage für Streupulver ist. Das Karbaniid ist osmotisch indifferent, löslich, gegenüber dem Gewebe harmlos und als körpereigene Substanz völlig ungiftig. Es kann als Grundlage für Streupulver zur Behandlung selbst größerer nässender Wunden dienen. Die Herstellung von Streupulvern erfolgt in der üblichen Weise durch 'Mischung des für die Behandlung vorgesehenen Arzneimittels niit dem 1`arbamid in staubfeiner Form. Beispiele. r. 2,5 g Isooktylhydrol#zupreiti werden- mit 97,5 g Karbamid in der Kugelmühle fein,gemahlen und die Mischung durch ein feines Haarsieb geschlagen.It has now been found (1a1 powdered pure carbamide is an excellent basis for scattering powder. The carbaniid is osmotically indifferent, soluble, harmless to the tissue and completely non-toxic as an endogenous substance. It can be used as the basis for scattering powder for the treatment of even larger weeping wounds to serve. Scattering powders are produced in the usual way by mixing them of the drug intended for the treatment with the 1'arbamide in dust-fine form Shape. Examples. r. 2.5 g of isooctylhydrol are prepared with 97.5 g of carbamide in the ball mill finely, ground and the mixture beaten through a fine hair sieve.
2. 5,o g fein gepulverte Borsäure werden niit 95,o g fein gepulvertem Karbamid gemischt.2. 5, o g finely powdered boric acid becomes 95, o g finely powdered Mixed carbamide.
3. ro Teile p-Aminobenzoesäureäthvlester «-erden mit c)o Teilen Karbamid, zu feinstem Pulver zerrieben, gemischt.3. ro parts of p-aminobenzoic acid ether "earths with c) o parts of carbamide, Grated to the finest powder, mixed.
4.. io Teile p Aminobenzoesäureäthvlester, j o Teile Wismutsubgallat, 8o Teile Karbamid -u-erden als feines Pulver gemischt, 5. 5 Teile in Amino-p-oxybenzoesäuren:ethvIester, 5 Teile Borsäure, 2; Teile Karbamid werden als feinstes Pulver gemischt.4 .. io parts p aminobenzoic acid ether, j o parts bismuth subgallate, 80 parts of carbamide and earth mixed as a fine powder, 5. 5 parts in amino-p-oxybenzoic acids: ethyl ester, 5 parts boric acid, 2; Parts of carbamide are mixed as the finest powder.
6. o,r Teile o-Dioxyphenyläthanolmethylamin, i oo Teile Karbamid «-erden in feinst verteilter Form gemischt.6. o, r parts of o-dioxyphenylethanolmethylamine, 100 parts of carbamide «earths mixed in finely divided form.
In gleicher Weise können andere Heilmittel, wie Isoamylhydrokuprein oder 2 # 6 # 9 - Äthoxvcliaminoakridinhvdrochlorid, mit Karbainid zu Streupulvern verarbeitet werden.In the same way, you can use other remedies, such as isoamylhydrocupreine or 2 # 6 # 9 - ethoxylaminoacridine hydrochloride, with carbainide to form powdered powders are processed.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF50596D DE381292C (en) | 1921-11-18 | 1921-11-18 | Process for the production of scattering powders |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF50596D DE381292C (en) | 1921-11-18 | 1921-11-18 | Process for the production of scattering powders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE381292C true DE381292C (en) | 1923-09-18 |
Family
ID=7103921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DEF50596D Expired DE381292C (en) | 1921-11-18 | 1921-11-18 | Process for the production of scattering powders |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE381292C (en) |
-
1921
- 1921-11-18 DE DEF50596D patent/DE381292C/en not_active Expired
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