DE3788955D1 - Pyridinyl-Derivate von 2-Aminoacetamid. - Google Patents

Pyridinyl-Derivate von 2-Aminoacetamid.

Info

Publication number
DE3788955D1
DE3788955D1 DE87118509T DE3788955T DE3788955D1 DE 3788955 D1 DE3788955 D1 DE 3788955D1 DE 87118509 T DE87118509 T DE 87118509T DE 3788955 T DE3788955 T DE 3788955T DE 3788955 D1 DE3788955 D1 DE 3788955D1
Authority
DE
Germany
Prior art keywords
pyridinyl
aminoacetamide
pyridinyl derivatives
phenyl
independently selected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE87118509T
Other languages
English (en)
Other versions
DE3788955T2 (de
Inventor
Ronald C Griffith
James J Napier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Fisons Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fisons Corp filed Critical Fisons Corp
Application granted granted Critical
Publication of DE3788955D1 publication Critical patent/DE3788955D1/de
Publication of DE3788955T2 publication Critical patent/DE3788955T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
DE87118509T 1987-02-06 1987-12-14 Pyridinyl-Derivate von 2-Aminoacetamid. Expired - Fee Related DE3788955T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/011,983 US4769466A (en) 1987-02-06 1987-02-06 2-aminoacetamide pyridinyl derivatives

Publications (2)

Publication Number Publication Date
DE3788955D1 true DE3788955D1 (de) 1994-03-10
DE3788955T2 DE3788955T2 (de) 1994-05-11

Family

ID=21752815

Family Applications (1)

Application Number Title Priority Date Filing Date
DE87118509T Expired - Fee Related DE3788955T2 (de) 1987-02-06 1987-12-14 Pyridinyl-Derivate von 2-Aminoacetamid.

Country Status (8)

Country Link
US (1) US4769466A (de)
EP (1) EP0278090B1 (de)
JP (1) JPH0825998B2 (de)
AT (1) ATE100798T1 (de)
CA (1) CA1299571C (de)
DE (1) DE3788955T2 (de)
IE (1) IE61880B1 (de)
PT (1) PT86251B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430044A (en) * 1987-02-06 1995-07-04 Fisons Corporation Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties
ES2083972T3 (es) * 1988-08-12 1996-05-01 Astra Ab Arilalquil-aminas y -amidas con propiedades anticonvulsivas y neuroprotectoras.
SG47949A1 (en) * 1991-10-30 1998-04-17 Astra Ab 2-Heterocyclicethylamine derivatives and their use as pharmaceuticals
US5541213A (en) * 1993-06-24 1996-07-30 Eisai Co., Ltd. Propenoic acid derivatives diazole propenoic acid compounds which have useful pharmaceutical utility
EP3564234B1 (de) * 2013-11-05 2021-09-29 AstraZeneca AB Nmda-antagonist-prodrugs
WO2018098344A1 (en) * 2016-11-28 2018-05-31 Biohaven Pharmaceutical Holding Company Ltd. Prodrugs of lanicemine and their method of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE955508C (de) * 1954-07-28 1957-01-03 Cilag Ag Verfahren zur Herstellung von antikonvulsivisch wirkenden Carbonsaeureamiden
CH343388A (de) * 1956-03-09 1959-12-31 Cilag Chemie Aktiengesellschaf Verfahren zur Herstellung neuer Amide
US4500714A (en) * 1981-10-15 1985-02-19 Chugai Seiyaku Kabushiki Kaisha 3-Substituted-ureido-N-pyridyl benzamides

Also Published As

Publication number Publication date
EP0278090A3 (en) 1990-04-11
IE872931L (en) 1988-08-06
DE3788955T2 (de) 1994-05-11
EP0278090A2 (de) 1988-08-17
ATE100798T1 (de) 1994-02-15
JPH0825998B2 (ja) 1996-03-13
PT86251A (en) 1987-12-01
CA1299571C (en) 1992-04-28
IE61880B1 (en) 1994-11-30
JPS63201169A (ja) 1988-08-19
EP0278090B1 (de) 1994-01-26
PT86251B (pt) 1991-02-08
US4769466A (en) 1988-09-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ASTRA AB, SOEDERTAELJE, SE

8339 Ceased/non-payment of the annual fee