DE3783084T2 - Chirale phosphinopyrrolidin-verbindungen und ihre verwendung fuer asymetrische synthese optisch aktiver verbindungen. - Google Patents

Chirale phosphinopyrrolidin-verbindungen und ihre verwendung fuer asymetrische synthese optisch aktiver verbindungen.

Info

Publication number
DE3783084T2
DE3783084T2 DE8787109039T DE3783084T DE3783084T2 DE 3783084 T2 DE3783084 T2 DE 3783084T2 DE 8787109039 T DE8787109039 T DE 8787109039T DE 3783084 T DE3783084 T DE 3783084T DE 3783084 T2 DE3783084 T2 DE 3783084T2
Authority
DE
Germany
Prior art keywords
compounds
phosphinopyrrolidin
chiral
optically active
active compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787109039T
Other languages
English (en)
Other versions
DE3783084D1 (de
Inventor
Kazuo Achiwa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP62052177A external-priority patent/JPS635094A/ja
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE3783084D1 publication Critical patent/DE3783084D1/de
Publication of DE3783084T2 publication Critical patent/DE3783084T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0073—Rhodium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C07C29/145—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones with hydrogen or hydrogen-containing gases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/48—Preparation of compounds having groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
DE8787109039T 1986-06-25 1987-06-24 Chirale phosphinopyrrolidin-verbindungen und ihre verwendung fuer asymetrische synthese optisch aktiver verbindungen. Expired - Fee Related DE3783084T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP61147167 1986-06-25
JP5217887 1987-03-09
JP62052177A JPS635094A (ja) 1987-03-09 1987-03-09 新規なホスフイノピロリジン化合物

Publications (2)

Publication Number Publication Date
DE3783084D1 DE3783084D1 (de) 1993-01-28
DE3783084T2 true DE3783084T2 (de) 1993-04-15

Family

ID=27294568

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787109039T Expired - Fee Related DE3783084T2 (de) 1986-06-25 1987-06-24 Chirale phosphinopyrrolidin-verbindungen und ihre verwendung fuer asymetrische synthese optisch aktiver verbindungen.

Country Status (5)

Country Link
US (1) US4879389A (de)
EP (1) EP0251164B1 (de)
CA (1) CA1337298C (de)
DE (1) DE3783084T2 (de)
ES (1) ES2052515T3 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0218970B1 (de) * 1985-10-18 1992-06-17 F. Hoffmann-La Roche Ag Chirale Rhodium-diphosphinkomplexe für asymmetrische Hydrierungen
JP2816555B2 (ja) * 1988-03-07 1998-10-27 富士薬品工業株式会社 新規なホスフイノピロリジン化合物およびそれを用いる不斉合成法
DE4001019A1 (de) * 1990-01-16 1991-07-18 Degussa Verfahren zur asymmetrischen hydrierung von (alpha)-ketocarbonylverbindungen zu optisch aktiven (alpha)-hydroxycarbonylverbindungen
DK0512416T3 (da) * 1991-05-03 1997-06-30 Hoechst Ag Nye homochirale diphosfiner
US5543559A (en) 1994-07-07 1996-08-06 Hoffman-La Roche Inc. Process for the enantioselective hydrogenation of ketosiophorone derivatives
US5777062A (en) * 1996-02-23 1998-07-07 Novartis Corporation Diphosphines bonded to side chains of polymers, and metal complexes thereof
WO1998023624A1 (fr) * 1996-11-29 1998-06-04 Fuji Yakuhin Kogyo Kabushiki Kaisha Nouveaux composes de phosphinopyrrolidine et procede de fabrication
US6307049B1 (en) 1998-09-30 2001-10-23 The Procter & Gamble Co. Heterocyclic 2-substituted ketoamides
US6300341B1 (en) 1998-09-30 2001-10-09 The Procter & Gamble Co. 2-substituted heterocyclic sulfonamides
DE19938709C1 (de) * 1999-08-14 2001-01-18 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Adrenalin
DE10002973A1 (de) * 2000-01-24 2001-07-26 Degussa Polymere Diphosphinliganden für homogen lösliche Hydrierkatalysatoren, Verfahren zu deren Herstellung und Verwendung
US20050197503A1 (en) * 2004-03-05 2005-09-08 Boehringer Ingelheim International Gmbh Process for the preparation of N-alkyl-N-methyl-3-hydroxy-3-(2-thienyl)-propylamines
DE102004033313A1 (de) 2004-07-08 2006-01-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung von Enantiomeren 3-hydroxy-3-phenyl-propylaminen
CN102381990A (zh) * 2010-08-31 2012-03-21 凯瑞斯德生化(苏州)有限公司 一种光学活性的n-苄基新福林的制备方法
CN103249484B (zh) 2010-11-29 2015-09-30 高砂香料工业株式会社 不对称氢化催化剂和利用它制备光学活性的羰基化合物的方法
CN104725173B (zh) * 2015-02-13 2017-01-11 万华化学集团股份有限公司 一种制备光学活性醛或酮的方法及其催化剂的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4343741A (en) * 1981-04-22 1982-08-10 Hoffmann-La Roche Inc. Chiral phosphines
US4539411A (en) * 1982-02-05 1985-09-03 Hoffmann-La Roche Inc. Rhodium complexes of chiral phosphines

Also Published As

Publication number Publication date
US4879389A (en) 1989-11-07
ES2052515T3 (es) 1994-07-16
EP0251164B1 (de) 1992-12-16
EP0251164A3 (en) 1989-07-05
EP0251164A2 (de) 1988-01-07
CA1337298C (en) 1995-10-10
DE3783084D1 (de) 1993-01-28

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee