DE3773800D1 - PROTEIN SYNTHESIS INHIBITOR, METHOD FOR THE PRODUCTION THEREOF, USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME. - Google Patents

PROTEIN SYNTHESIS INHIBITOR, METHOD FOR THE PRODUCTION THEREOF, USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME.

Info

Publication number
DE3773800D1
DE3773800D1 DE8787401656T DE3773800T DE3773800D1 DE 3773800 D1 DE3773800 D1 DE 3773800D1 DE 8787401656 T DE8787401656 T DE 8787401656T DE 3773800 T DE3773800 T DE 3773800T DE 3773800 D1 DE3773800 D1 DE 3773800D1
Authority
DE
Germany
Prior art keywords
pharmaceutical compositions
production
same
compositions containing
protein synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787401656T
Other languages
German (de)
Inventor
Luigi Barbieri
Pierre Casellas
Fiorenzo Stirpe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Application granted granted Critical
Publication of DE3773800D1 publication Critical patent/DE3773800D1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A61K36/428—Trichosanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Botany (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The present invention relates to a novel glycoprotein, extracted from the seeds of Trichosanthes kirilowii, called: trichokirin, as well as to its modified derivatives containing a free or blocked SH group. It relates to a process for its preparation, to its use and to pharmaceutical compositions in which it is present.
DE8787401656T 1986-07-15 1987-07-15 PROTEIN SYNTHESIS INHIBITOR, METHOD FOR THE PRODUCTION THEREOF, USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME. Expired - Fee Related DE3773800D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8610296A FR2601680B1 (en) 1986-07-15 1986-07-15 PROTEIN SYNTHESIS INHIBITOR, ISOLATION METHOD, USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

Publications (1)

Publication Number Publication Date
DE3773800D1 true DE3773800D1 (en) 1991-11-21

Family

ID=9337439

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787401656T Expired - Fee Related DE3773800D1 (en) 1986-07-15 1987-07-15 PROTEIN SYNTHESIS INHIBITOR, METHOD FOR THE PRODUCTION THEREOF, USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME.

Country Status (15)

Country Link
US (1) US5037960A (en)
EP (1) EP0256907B1 (en)
JP (1) JPS6323900A (en)
KR (1) KR880001698A (en)
AT (1) ATE68351T1 (en)
AU (1) AU594482B2 (en)
DE (1) DE3773800D1 (en)
DK (1) DK369387A (en)
ES (1) ES2038680T3 (en)
FR (1) FR2601680B1 (en)
GR (1) GR3002918T3 (en)
IL (1) IL83182A (en)
NZ (1) NZ221066A (en)
PT (1) PT85316B (en)
ZA (1) ZA875175B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990011767A1 (en) * 1989-04-04 1990-10-18 Genelabs Incorporated Purified trichosanthin and method of preparation
GB9007384D0 (en) * 1990-04-02 1990-05-30 Duncan Ruth Coupling between polymers and other organic molecular entities utilising thiol-specific reactive groups
DE69131253T2 (en) * 1990-10-09 2000-02-24 New York University New York USEFUL VEGETABLE PROTEIN FOR TREATING TUMORS AND HIV INFECTIONS
AU672749B2 (en) * 1991-04-15 1996-10-17 American Biosciences, Inc An anti-HIV protein, TAP 29, from trichosanthes, DNA coding therefor and therapeutic uses thereof
CN1056383C (en) * 1997-11-29 2000-09-13 中国科学院昆明动物研究所 Chinese trichosanthes protein, preparation method and use in pharmacy
US20090181409A1 (en) * 2008-01-10 2009-07-16 Ye Fang Optical biosensor method for cell-cell interaction
US20100240990A1 (en) * 2009-03-19 2010-09-23 Besiki Surguladze Diagnosis and treatment method of malignant tumours and marker compound

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2437213A1 (en) * 1978-09-28 1980-04-25 Cm Ind CYTOTOXIC PRODUCTS FORMED BY COVALENT BINDING OF THE CHAIN TO RICIN WITH AN ANTIBODY AND THEIR PREPARATION METHOD
FR2566271B1 (en) * 1984-06-20 1986-11-07 Sanofi Sa NOVEL CYTOTOXIC CONJUGATES FOR USE IN THERAPEUTICS AND PROCESS FOR OBTAINING SAME
US4744981A (en) * 1985-10-17 1988-05-17 Neorx Corporation Trichothecene antibody conjugates

Also Published As

Publication number Publication date
AU7539787A (en) 1988-01-21
GR3002918T3 (en) 1993-01-25
PT85316B (en) 1990-04-30
NZ221066A (en) 1991-02-26
PT85316A (en) 1987-08-01
IL83182A (en) 1992-05-25
DK369387A (en) 1988-01-16
ES2038680T3 (en) 1993-08-01
ZA875175B (en) 1988-03-30
US5037960A (en) 1991-08-06
KR880001698A (en) 1988-04-26
ATE68351T1 (en) 1991-11-15
JPS6323900A (en) 1988-02-01
EP0256907B1 (en) 1991-10-16
EP0256907A1 (en) 1988-02-24
DK369387D0 (en) 1987-07-15
AU594482B2 (en) 1990-03-08
FR2601680B1 (en) 1990-06-29
FR2601680A1 (en) 1988-01-22
IL83182A0 (en) 1987-12-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee