ATE125707T1 - KAWA-KAWA EXTRACT, PROCESS FOR ITS PRODUCTION AND ITS USE. - Google Patents

KAWA-KAWA EXTRACT, PROCESS FOR ITS PRODUCTION AND ITS USE.

Info

Publication number
ATE125707T1
ATE125707T1 AT91915521T AT91915521T ATE125707T1 AT E125707 T1 ATE125707 T1 AT E125707T1 AT 91915521 T AT91915521 T AT 91915521T AT 91915521 T AT91915521 T AT 91915521T AT E125707 T1 ATE125707 T1 AT E125707T1
Authority
AT
Austria
Prior art keywords
extract
content
kawa
flavokavin
solution
Prior art date
Application number
AT91915521T
Other languages
German (de)
Inventor
Klaus-Peter Schwabe
Original Assignee
Schwabe Willmar Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schwabe Willmar Gmbh & Co filed Critical Schwabe Willmar Gmbh & Co
Application granted granted Critical
Publication of ATE125707T1 publication Critical patent/ATE125707T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicinal Preparation (AREA)

Abstract

Described is a dry kava extract with a total kavalactone content of at least 50 % by wt. and a flavokavin content of at the most 0.3 % by wt. The extract is readily soluble in water and has high bio-availability following oral administration. In order to increase the kavalactone content and decrease the flavokavin content of the extract, a method is proposed in which the raw extract is brought into solution and the flavokavin content reduced by cold precipitation or by solvent partition, after which the solution is concentrated to dryness. The dry extract can be used to prepare drugs.
AT91915521T 1990-09-12 1991-09-05 KAWA-KAWA EXTRACT, PROCESS FOR ITS PRODUCTION AND ITS USE. ATE125707T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4028945A DE4028945A1 (en) 1990-09-12 1990-09-12 KAWA-KAWA EXTRACT, METHOD FOR PRODUCING IT AND ITS USE

Publications (1)

Publication Number Publication Date
ATE125707T1 true ATE125707T1 (en) 1995-08-15

Family

ID=6414114

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91915521T ATE125707T1 (en) 1990-09-12 1991-09-05 KAWA-KAWA EXTRACT, PROCESS FOR ITS PRODUCTION AND ITS USE.

Country Status (7)

Country Link
EP (1) EP0505519B1 (en)
JP (1) JPH05502457A (en)
AT (1) ATE125707T1 (en)
DE (2) DE4028945A1 (en)
DK (1) DK0505519T3 (en)
ES (1) ES2076543T3 (en)
WO (1) WO1992004036A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4401646A1 (en) * 1994-01-21 1995-07-27 Krewel Werke Gmbh Optimally releasing kava extracts
FR2771002B1 (en) * 1997-11-17 2000-03-31 Sederma Sa COMPOSITIONS FOR COSMETIC OR DERMOPHARMACEUTICAL USE CONTAINING A PLANT EXTRACT OBTAINED FROM THE ROOTS OF KAVA PIPER METHYSTICUM
EP0987026A1 (en) * 1998-08-21 2000-03-22 Max Zeller Söhne AG Process of preparation of a Kawa-Kawa Extract
NL1011082C2 (en) * 1999-01-20 2000-07-21 Danny Van Eijsselsteijn Herbal composition for increasing erogenous sensitivity, especially in women, comprises muira puama and damiana
WO2002007743A2 (en) * 2000-07-26 2002-01-31 Vitaplant Ag Piper methysticum plant extract
EP1222925B1 (en) 2000-12-18 2005-02-23 Meiji Dairies Corporation Kavalactone as TNF-alpha production inhibitor
WO2005021017A1 (en) * 2003-08-27 2005-03-10 Finzelberg Gmbh & Co. Kg Alkaloid-reduced kava extract
CN100456937C (en) * 2004-09-24 2009-02-04 余内逊 Process for preparing kawa sleeping aid and tonifying gastric juice soy-milk powder
JP5548916B2 (en) * 2009-03-04 2014-07-16 公益財団法人岐阜県研究開発財団 Pharmaceutical preparations containing Kawalactone derivatives
AU2012223307A1 (en) * 2011-03-01 2013-08-29 Phytomedics Corporation Inc. Methods of processing extracts of a T. wilfordii Hook F. plant

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE197806C (en) *
GB943121A (en) * 1961-05-24 1963-11-27 Thomae Gmbh Dr K Medicines containing lactones from piper methysticum
DE1617812A1 (en) * 1967-06-05 1972-02-17 Spezialchemie Gmbh & Co Process for the production of endoanaesthetic solutions of active ingredients in kava
DE3303398A1 (en) * 1983-02-02 1984-08-02 Ewald Dr.med.vet. 2060 Bad Oldesloe Karstens Product for maintaining and enhancing mental and physical performance

Also Published As

Publication number Publication date
DK0505519T3 (en) 1995-09-18
DE4028945A1 (en) 1992-03-19
WO1992004036A1 (en) 1992-03-19
DE59106162D1 (en) 1995-09-07
EP0505519A1 (en) 1992-09-30
JPH05502457A (en) 1993-04-28
ES2076543T3 (en) 1995-11-01
EP0505519B1 (en) 1995-08-02

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Legal Events

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