DE3770308D1 - Methacryl-polymer- oder copolymer-nanopartikel, verfahren zu ihrer herstellung und ihre anwendung als arzneimittelvektor. - Google Patents

Methacryl-polymer- oder copolymer-nanopartikel, verfahren zu ihrer herstellung und ihre anwendung als arzneimittelvektor.

Info

Publication number
DE3770308D1
DE3770308D1 DE8787400695T DE3770308T DE3770308D1 DE 3770308 D1 DE3770308 D1 DE 3770308D1 DE 8787400695 T DE8787400695 T DE 8787400695T DE 3770308 T DE3770308 T DE 3770308T DE 3770308 D1 DE3770308 D1 DE 3770308D1
Authority
DE
Germany
Prior art keywords
production
methacrylic polymer
copolymer nanoparticles
medicine vector
medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787400695T
Other languages
English (en)
Inventor
Roger Leverge
Alain Rolland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Rennes 1
Original Assignee
Universite de Rennes 1
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite de Rennes 1 filed Critical Universite de Rennes 1
Application granted granted Critical
Publication of DE3770308D1 publication Critical patent/DE3770308D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
    • A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A61K49/1878—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles the nanoparticle having a magnetically inert core and a (super)(para)magnetic coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DE8787400695T 1986-03-28 1987-03-27 Methacryl-polymer- oder copolymer-nanopartikel, verfahren zu ihrer herstellung und ihre anwendung als arzneimittelvektor. Expired - Lifetime DE3770308D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8604535A FR2596399B1 (fr) 1986-03-28 1986-03-28 Nanoparticules a base de polymere ou copolymere methacrylique, procede de preparation, et application comme vecteur de medicament

Publications (1)

Publication Number Publication Date
DE3770308D1 true DE3770308D1 (de) 1991-07-04

Family

ID=9333692

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787400695T Expired - Lifetime DE3770308D1 (de) 1986-03-28 1987-03-27 Methacryl-polymer- oder copolymer-nanopartikel, verfahren zu ihrer herstellung und ihre anwendung als arzneimittelvektor.

Country Status (4)

Country Link
EP (1) EP0240424B1 (de)
DE (1) DE3770308D1 (de)
ES (1) ES2029844T3 (de)
FR (1) FR2596399B1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4925678A (en) * 1987-04-01 1990-05-15 Ranney David F Endothelial envelopment drug carriers
US5108759A (en) * 1987-04-01 1992-04-28 Ranney David F Endothelial envelopment drug carriers
FR2631826B1 (fr) * 1988-05-27 1992-06-19 Centre Nat Rech Scient Vecteur particulaire utile notamment pour le transport de molecules a activite biologique et procede pour sa preparation
US5078994A (en) * 1990-04-12 1992-01-07 Eastman Kodak Company Microgel drug delivery system
US5401492A (en) * 1992-12-17 1995-03-28 Sterling Winthrop, Inc. Water insoluble non-magnetic manganese particles as magnetic resonance contract enhancement agents
US6106866A (en) * 1995-07-31 2000-08-22 Access Pharmaceuticals, Inc. In vivo agents comprising cationic drugs, peptides and metal chelators with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles, including tumor sites
DE19746362A1 (de) * 1996-10-23 1998-04-30 Sueddeutsche Kalkstickstoff Verfahren zur Herstellung von biologisch aktiven Polymernanopartikel-Nucleinsäure-Konjugaten
EP1031354A3 (de) * 1999-01-19 2003-02-05 Rohm And Haas Company Polymere MRI Kontrastmittel
DE19961277A1 (de) * 1999-12-18 2001-06-21 Cognis Deutschland Gmbh Verwendung von nanoskaligen Polymeren
KR100466545B1 (ko) * 2002-02-19 2005-01-15 한국전자통신연구원 고분자 나노 입자 제조방법
US20040161466A1 (en) 2003-02-14 2004-08-19 Biocompatibles Uk Limited Chemoembolisation
GB2407500A (en) * 2003-11-03 2005-05-04 Ist Superiore Sanita Use of microparticles for antigen delivery
US8012457B2 (en) 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
US8303931B2 (en) 2006-02-17 2012-11-06 Topass Gmbh Multimodal imaging using a three compartment polymer nanoparticle with cell specificity
BR112016005768B1 (pt) 2013-09-19 2021-09-21 Microvention, Inc Películas de polímero
US9546236B2 (en) 2013-09-19 2017-01-17 Terumo Corporation Polymer particles
CA2929235C (en) 2013-11-08 2018-07-17 Terumo Corporation Polymer particles
EP2963103A1 (de) * 2014-07-04 2016-01-06 Henkel AG & Co. KGaA pH-sensitive Nanokapseln
WO2016154592A1 (en) 2015-03-26 2016-09-29 Microvention, Inc. Embiolic particles
JP6653047B2 (ja) 2016-09-28 2020-02-26 テルモ株式会社 ポリマー粒子

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK143689C (da) * 1975-03-20 1982-03-15 J Kreuter Fremgangsmaade til fremstilling af en adsorberet vaccine

Also Published As

Publication number Publication date
EP0240424B1 (de) 1991-05-29
FR2596399A1 (fr) 1987-10-02
ES2029844T3 (es) 1992-10-01
EP0240424A1 (de) 1987-10-07
FR2596399B1 (fr) 1988-09-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee