DE3688983T2 - Faktor IX-Protein. - Google Patents

Faktor IX-Protein.

Info

Publication number
DE3688983T2
DE3688983T2 DE19863688983 DE3688983T DE3688983T2 DE 3688983 T2 DE3688983 T2 DE 3688983T2 DE 19863688983 DE19863688983 DE 19863688983 DE 3688983 T DE3688983 T DE 3688983T DE 3688983 T2 DE3688983 T2 DE 3688983T2
Authority
DE
Germany
Prior art keywords
protein
factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE19863688983
Other languages
English (en)
Other versions
DE3688983D1 (de
Inventor
Donald Stewart Anson
George Gow Brownlee
Ian Martin Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
British Technology Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858506767A external-priority patent/GB8506767D0/en
Priority claimed from GB858515416A external-priority patent/GB8515416D0/en
Application filed by British Technology Group Ltd filed Critical British Technology Group Ltd
Publication of DE3688983D1 publication Critical patent/DE3688983D1/de
Application granted granted Critical
Publication of DE3688983T2 publication Critical patent/DE3688983T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE19863688983 1985-03-15 1986-03-12 Faktor IX-Protein. Expired - Lifetime DE3688983T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858506767A GB8506767D0 (en) 1985-03-15 1985-03-15 Factor 1x protein
GB858515416A GB8515416D0 (en) 1985-06-18 1985-06-18 Factor ix protein

Publications (2)

Publication Number Publication Date
DE3688983D1 DE3688983D1 (de) 1993-10-07
DE3688983T2 true DE3688983T2 (de) 1994-02-17

Family

ID=26288979

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8686301791T Expired - Lifetime DE3684947D1 (de) 1985-03-15 1986-03-12 Faktor-ix-protein.
DE19863688983 Expired - Lifetime DE3688983T2 (de) 1985-03-15 1986-03-12 Faktor IX-Protein.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE8686301791T Expired - Lifetime DE3684947D1 (de) 1985-03-15 1986-03-12 Faktor-ix-protein.

Country Status (3)

Country Link
EP (2) EP0430930B1 (de)
JP (1) JPH082300B2 (de)
DE (2) DE3684947D1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4770999A (en) * 1985-04-22 1988-09-13 Genetics Institute, Inc. High yield production of active Factor IX
FR2599752B1 (fr) * 1986-06-10 1989-11-03 Transgene Sa Variants de l'alpha1- antitrypsine utiles notamment comme inhibiteurs de la kallikreine
FR2600334B1 (fr) * 1986-06-23 1989-05-12 Transgene Sa Vecteurs d'integration dans les cellules eucaryotes assurant l'expression du facteur ix, lignees celullaires obtenues et procede pour leur preparation
EP0289586A4 (de) * 1986-11-17 1990-04-10 New England Medical Ct Steigerung der gamma-carboxylation von rekombinanten, vitamin-k-abhängigen proteinen.
US5648254A (en) * 1988-01-15 1997-07-15 Zymogenetics, Inc. Co-expression in eukaryotic cells
US5120537A (en) * 1989-06-14 1992-06-09 Oklahoma Medical Research Foundation Factor xa based anticoagulant compositions
GB9122609D0 (en) * 1991-10-24 1991-12-04 Brownlee George G Improvements relating to the treatment of haemophilia
US5484720A (en) * 1994-09-08 1996-01-16 Genentech, Inc. Methods for calcium phosphate transfection
DK0779931T3 (da) * 1994-09-08 2003-03-03 Genentech Inc Fremgangsmåder til udførelse af calciumphosphattransfektion
DE4435520A1 (de) * 1994-10-04 1996-04-11 Immuno Ag Verfahren zur Trennung von rekombinantem pro-Faktor IX von rekombinantem Faktor IX
JP2002531093A (ja) 1998-12-01 2002-09-24 アベンティス、パストゥール、リミテッド クラミジア抗原および対応するｄｎａ断片ならびにその使用
AU2002226028A1 (en) 2000-11-14 2002-05-27 Board Of Regents, Unversity Of Texas Systems Mutant human factor ix with an increased resistance to inhibition by heparin
WO2005033140A1 (ja) * 2003-09-30 2005-04-14 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute 高純度血液凝固ｉｘ因子調製物およびその精製方法
US7829745B1 (en) 2009-08-18 2010-11-09 Corning Incorporated Methods for selectively synthesizing 1-aryl-2-tetralones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125409B (en) * 1982-08-04 1985-11-13 Nat Res Dev Genetic engineering
FR2564106B1 (fr) * 1984-05-09 1988-04-22 Transgene Sa Vecteurs d'expression du facteur ix, cellules transformees par ces vecteurs et procede de preparation du facteur ix.

Also Published As

Publication number Publication date
JPS61263926A (ja) 1986-11-21
DE3684947D1 (de) 1992-05-27
EP0430930B1 (de) 1993-09-01
JPH082300B2 (ja) 1996-01-17
DE3688983D1 (de) 1993-10-07
EP0195592A3 (en) 1987-06-24
EP0430930A1 (de) 1991-06-05
EP0195592A2 (de) 1986-09-24
EP0195592B1 (de) 1992-04-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition