DE3688870D1 - Dns-sequenz. - Google Patents

Dns-sequenz.

Info

Publication number
DE3688870D1
DE3688870D1 DE8686902345T DE3688870T DE3688870D1 DE 3688870 D1 DE3688870 D1 DE 3688870D1 DE 8686902345 T DE8686902345 T DE 8686902345T DE 3688870 T DE3688870 T DE 3688870T DE 3688870 D1 DE3688870 D1 DE 3688870D1
Authority
DE
Germany
Prior art keywords
dna
dna fragment
desired polypeptide
sequence
coding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686902345T
Other languages
English (en)
Other versions
DE3688870T2 (de
Inventor
Henrik Andersen
Hans Dahl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Application granted granted Critical
Publication of DE3688870D1 publication Critical patent/DE3688870D1/de
Publication of DE3688870T2 publication Critical patent/DE3688870T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Diabetes (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE86902345T 1985-04-03 1986-04-03 Dns-sequenz. Expired - Fee Related DE3688870T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK151585A DK151585D0 (da) 1985-04-03 1985-04-03 Dna-sekvens

Publications (2)

Publication Number Publication Date
DE3688870D1 true DE3688870D1 (de) 1993-09-16
DE3688870T2 DE3688870T2 (de) 1993-12-23

Family

ID=8105641

Family Applications (1)

Application Number Title Priority Date Filing Date
DE86902345T Expired - Fee Related DE3688870T2 (de) 1985-04-03 1986-04-03 Dns-sequenz.

Country Status (7)

Country Link
EP (1) EP0218651B1 (de)
JP (1) JP2612264B2 (de)
AT (1) ATE92961T1 (de)
AU (1) AU5695086A (de)
DE (1) DE3688870T2 (de)
DK (2) DK151585D0 (de)
WO (1) WO1986005804A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340725A (en) * 1986-10-09 1994-08-23 Fujisawa Pharmaceutical Co., Ltd. Expression vector for insulin-like growth factor I and method of production
EP0264074B1 (de) * 1986-10-09 1992-12-30 Fujisawa Pharmaceutical Co., Ltd. Expressionsvektor für menschlichen insulinähnlichen Wachstumsfaktor-I
WO1990005185A1 (fr) * 1988-11-07 1990-05-17 L'universite De L'etat A Liege Hormone de croissance humaine modifiee
US20080076706A1 (en) 1997-07-14 2008-03-27 Bolder Biotechnology, Inc. Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof
ATE375363T1 (de) * 1997-07-14 2007-10-15 Bolder Biotechnology Inc Derivate des wachstumshormons und verwandte proteine
US6753165B1 (en) 1999-01-14 2004-06-22 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
US8288126B2 (en) 1999-01-14 2012-10-16 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
US7446183B2 (en) 2000-06-16 2008-11-04 Asterion Limited Fusion protein comprising growth hormone and growth hormone receptor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009930B2 (de) * 1978-10-10 1988-08-24 The Board Of Trustees Of The Leland Stanford Junior University Rekombinante DNA, Verfahren zu ihrer Herstellung und Herstellung fremder Proteine durch einzellige Wirte, die sie enthalten
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
CA1200773A (en) * 1980-02-29 1986-02-18 William J. Rutter Expression linkers
JPS5967297A (ja) * 1982-10-08 1984-04-16 Kyowa Hakko Kogyo Co Ltd 新規ベクタ−
DE3247922A1 (de) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten
US4755465A (en) * 1983-04-25 1988-07-05 Genentech, Inc. Secretion of correctly processed human growth hormone in E. coli and Pseudomonas
JPS60502136A (ja) * 1983-08-10 1985-12-12 アムジエン　インコーポレイテツド 微生物によるインタ−ル−キン２の形質発現

Also Published As

Publication number Publication date
JP2612264B2 (ja) 1997-05-21
DE3688870T2 (de) 1993-12-23
DK580886D0 (da) 1986-12-03
DK151585D0 (da) 1985-04-03
ATE92961T1 (de) 1993-08-15
DK580886A (da) 1986-12-03
EP0218651B1 (de) 1993-08-11
EP0218651A1 (de) 1987-04-22
JPS62502657A (ja) 1987-10-15
WO1986005804A1 (en) 1986-10-09
AU5695086A (en) 1986-10-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee