DE3678680D1 - Alpha-tocopherol(halo)uridin-diester von phosphorsaeure, deren salze und verfahren zu deren herstellung. - Google Patents

Alpha-tocopherol(halo)uridin-diester von phosphorsaeure, deren salze und verfahren zu deren herstellung.

Info

Publication number
DE3678680D1
DE3678680D1 DE8686114793T DE3678680T DE3678680D1 DE 3678680 D1 DE3678680 D1 DE 3678680D1 DE 8686114793 T DE8686114793 T DE 8686114793T DE 3678680 T DE3678680 T DE 3678680T DE 3678680 D1 DE3678680 D1 DE 3678680D1
Authority
DE
Germany
Prior art keywords
uridine
diester
tocopherol
halo
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686114793T
Other languages
English (en)
Inventor
Kazumi Ogata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3678680D1 publication Critical patent/DE3678680D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE8686114793T 1985-12-18 1986-10-24 Alpha-tocopherol(halo)uridin-diester von phosphorsaeure, deren salze und verfahren zu deren herstellung. Expired - Fee Related DE3678680D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60284940A JPS62265299A (ja) 1985-12-18 1985-12-18 α―トコフェロールとウリジンとのリン酸ジエステル，そのハロゲン置換体もしくはこれらの塩およびそれらの製造法

Publications (1)

Publication Number Publication Date
DE3678680D1 true DE3678680D1 (de) 1991-05-16

Family

ID=17685034

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686114793T Expired - Fee Related DE3678680D1 (de) 1985-12-18 1986-10-24 Alpha-tocopherol(halo)uridin-diester von phosphorsaeure, deren salze und verfahren zu deren herstellung.

Country Status (6)

Country Link
US (1) US4742163A (de)
EP (1) EP0226753B1 (de)
JP (1) JPS62265299A (de)
CA (1) CA1271191A (de)
DE (1) DE3678680D1 (de)
ES (1) ES2021574B3 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4849515A (en) * 1988-08-22 1989-07-18 E. I. Du Pont De Nemours And Company Clindamycin-2-phosphoryl benzylate
FR2657526B1 (fr) * 1990-01-31 1994-10-28 Lvmh Rech Utilisation d'un phosphate d'alpha-tocopherol, ou de l'un de ses derives, pour la preparation de compositions cosmetiques, dermatologiques, ou pharmaceutiques; compositions ainsi obtenues.
US7115585B2 (en) * 2000-08-21 2006-10-03 Inspire Pharmaceuticals, Inc. Compositions for treating epithelial and retinal tissue diseases
AT500404A1 (de) * 2003-07-17 2005-12-15 Jsw Res Forschungslabor Gmbh Chemische verbindungen enthaltend tocopherol sowie zumindest einen weiteren pharmazeutischen wirkstoff
EP3204004A4 (de) * 2014-10-08 2018-05-30 Epigenetics Pharma LLC Vitamin-e-nukleosidprodrugs
DE102019213606B4 (de) * 2019-09-06 2022-04-21 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Oligomer oder polymer, zusammensetzung sowie verwendung des oligomers oder polymers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1042839A (en) * 1963-12-19 1966-09-14 Asahi Chemical Ind Production of 5'-nucleotides
EP0073826A1 (de) * 1981-03-10 1983-03-16 Bioresearch Inc. Schnelle herstellung in fester phase von oligonukleotiden unter verwendung von phosphoroxychlorid
DE3263939D1 (en) * 1981-12-09 1985-07-04 Teijin Ltd 5-fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof

Also Published As

Publication number Publication date
ES2021574B3 (es) 1991-11-16
EP0226753A3 (en) 1988-07-06
JPH0127079B2 (de) 1989-05-26
CA1271191A (en) 1990-07-03
EP0226753A2 (de) 1987-07-01
JPS62265299A (ja) 1987-11-18
US4742163A (en) 1988-05-03
EP0226753B1 (de) 1991-04-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee