DE3667662D1 - Pyrazinderivate. - Google Patents

Pyrazinderivate.

Info

Publication number
DE3667662D1
DE3667662D1 DE8686103407T DE3667662T DE3667662D1 DE 3667662 D1 DE3667662 D1 DE 3667662D1 DE 8686103407 T DE8686103407 T DE 8686103407T DE 3667662 T DE3667662 T DE 3667662T DE 3667662 D1 DE3667662 D1 DE 3667662D1
Authority
DE
Germany
Prior art keywords
pyrazinderivate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686103407T
Other languages
German (de)
English (en)
Inventor
Toshio Wakabayashi
Hirokazu Hasegawa
Akihiro Ohta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo Corp
Original Assignee
Terumo Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terumo Corp filed Critical Terumo Corp
Application granted granted Critical
Publication of DE3667662D1 publication Critical patent/DE3667662D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8686103407T 1985-03-15 1986-03-13 Pyrazinderivate. Expired - Fee Related DE3667662D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5211585 1985-03-15

Publications (1)

Publication Number Publication Date
DE3667662D1 true DE3667662D1 (en) 1990-01-25

Family

ID=12905868

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686103407T Expired - Fee Related DE3667662D1 (en) 1985-03-15 1986-03-13 Pyrazinderivate.

Country Status (4)

Country Link
US (1) US4788197A (fr)
EP (1) EP0194686B1 (fr)
JP (2) JPS625970A (fr)
DE (1) DE3667662D1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI873428A (fi) * 1986-08-18 1988-02-19 Houston Biotechnology Oftalmologiska kompositioner foer behandling av nervdegenerationer.
EP0397859A4 (en) * 1987-11-12 1990-12-19 Terumo Kabushiki Kaisha Pyrazine derivatives and medicinal preparation containing same
US7030152B1 (en) 1997-04-02 2006-04-18 The Brigham And Women's Hospital, Inc. Systematic inflammatory markers as diagnostic tools in the prevention of atherosclerotic diseases and as tools to aid in the selection of agents to be used for the prevention and treatment of atherosclerotic disease
PT1003501E (pt) * 1997-04-02 2005-07-29 Brigham & Womens Hospital Utilizacao de um agente para reduzir o risco de doencas cardiovasculares
KR20030031886A (ko) * 2000-02-16 2003-04-23 뉴로젠 코포레이션 치환된 아릴피라진
AP2003002924A0 (en) * 2001-06-12 2003-12-31 Neurogen Corp 2,5-diarylpyrazines, 2,5 - diarylpyridines and 2,5 - diarylpyrimidines as CRF1 receptor modulators
CA2496197A1 (fr) * 2002-08-20 2004-03-04 Neurogen Corporation 2-arylpyrazines substituees en 5 comme modulateurs sur les recepteurs crf
GB0229747D0 (en) 2002-12-20 2003-01-29 Axis Shield Asa Assay
US7326706B2 (en) * 2003-08-15 2008-02-05 Bristol-Myers Squibb Company Pyrazine modulators of cannabinoid receptors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046763A (en) * 1968-11-08 1977-09-06 Mcneil Laboratories, Incorporated 2,3-Diphenyl-5-ethylpyrazine
US4064124A (en) * 1974-05-25 1977-12-20 Basf Aktiengesellschaft Manufacture of pyrazines

Also Published As

Publication number Publication date
JPH0615533B2 (ja) 1994-03-02
JPS62270564A (ja) 1987-11-24
US4788197A (en) 1988-11-29
EP0194686B1 (fr) 1989-12-20
EP0194686A1 (fr) 1986-09-17
JPS625970A (ja) 1987-01-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee