DE3578042D1 - Arzneimittel die prostaglandin i2 enthalten. - Google Patents

Arzneimittel die prostaglandin i2 enthalten.

Info

Publication number
DE3578042D1
DE3578042D1 DE8585305611T DE3578042T DE3578042D1 DE 3578042 D1 DE3578042 D1 DE 3578042D1 DE 8585305611 T DE8585305611 T DE 8585305611T DE 3578042 T DE3578042 T DE 3578042T DE 3578042 D1 DE3578042 D1 DE 3578042D1
Authority
DE
Germany
Prior art keywords
group
effect
methyl
carbon atoms
prostaglandin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585305611T
Other languages
German (de)
English (en)
Inventor
Akira Ishibashi
Daijiro Horii
Toshiji Kanayama
Katsuhiko Iseki
Masaki Shinoda
Chiyoko Ishiyama
Yosio Hayashi
Masakatsu Shibasaki
Mikiko Sodeoka
Yuji Ogawa
Toshiaki Mase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Yuka Pharmaceutical Co Ltd
Sagami Chemical Research Institute
Original Assignee
Mitsubishi Yuka Pharmaceutical Co Ltd
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Yuka Pharmaceutical Co Ltd, Sagami Chemical Research Institute filed Critical Mitsubishi Yuka Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3578042D1 publication Critical patent/DE3578042D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8585305611T 1984-08-09 1985-08-07 Arzneimittel die prostaglandin i2 enthalten. Expired - Lifetime DE3578042D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59165669A JPS6144819A (ja) 1984-08-09 1984-08-09 プロスタグランジンｉ２類縁化合物を含有する循環改善作用を有する薬剤

Publications (1)

Publication Number Publication Date
DE3578042D1 true DE3578042D1 (de) 1990-07-12

Family

ID=15816768

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585305611T Expired - Lifetime DE3578042D1 (de) 1984-08-09 1985-08-07 Arzneimittel die prostaglandin i2 enthalten.

Country Status (4)

Country Link
US (1) US4699921A (enExample)
JP (1) JPS6144819A (enExample)
AT (1) ATE53295T1 (enExample)
DE (1) DE3578042D1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0171992B1 (en) * 1984-08-09 1990-06-06 Mitsubishi Kasei Corporation Pharmaceuticals containing prostaglandin i2
JPS61289034A (ja) * 1985-06-17 1986-12-19 Teijin Ltd イソカルバサイクリン類脂肪乳剤
JPH0680027B2 (ja) * 1985-09-18 1994-10-12 財団法人相模中央化学研究所 プロスタサイクリン類及びこれらを含有する薬剤
DE3608088C2 (de) * 1986-03-07 1995-11-16 Schering Ag Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten
EP0431571A3 (en) * 1989-12-05 1992-01-02 Sagami Chemical Research Center Cis-bicyclo(4.3.0)non-2-ene derivatives
CA2133334A1 (en) * 1993-02-03 1994-08-04 Atsuo Hazato External skin treatment agent composition containing prostacyclins as active ingredient
CN1787824A (zh) * 2003-06-25 2006-06-14 有限会社循环器研究所 性交功能改善用外用制剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59137445A (ja) * 1983-01-27 1984-08-07 Teijin Ltd プロスタサイクリン類及びその製法
DE3474017D1 (en) * 1983-07-26 1988-10-20 Sankyo Co New carbacyclin derivatives, processes for their preparation and compositions containing them
DE3477776D1 (en) * 1983-08-19 1989-05-24 Sagami Chem Res Bicycloû3.3.0¨octane derivative and preparation thereof

Also Published As

Publication number Publication date
US4699921A (en) 1987-10-13
JPS6144819A (ja) 1986-03-04
JPH0244452B2 (enExample) 1990-10-04
ATE53295T1 (de) 1990-06-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee