DE3577850D1 - Tetracyclische verbindungen, verfahren zu ihrer herstellung und eine diese enthaltende pharmazeutische zusammensetzung. - Google Patents

Tetracyclische verbindungen, verfahren zu ihrer herstellung und eine diese enthaltende pharmazeutische zusammensetzung.

Info

Publication number
DE3577850D1
DE3577850D1 DE8585107681T DE3577850T DE3577850D1 DE 3577850 D1 DE3577850 D1 DE 3577850D1 DE 8585107681 T DE8585107681 T DE 8585107681T DE 3577850 T DE3577850 T DE 3577850T DE 3577850 D1 DE3577850 D1 DE 3577850D1
Authority
DE
Germany
Prior art keywords
production
pharmaceutical composition
composition containing
tetracyclic compounds
tetracyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585107681T
Other languages
English (en)
Inventor
Masanobu Kohsaka
Hiroshi Terano
Tadaaki Komori
Morita Iwami
Michio Yamashita
Masashi Hashimoto
Itsuo Uchida
Shigehiro Takase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848416141A external-priority patent/GB8416141D0/en
Priority claimed from GB858510378A external-priority patent/GB8510378D0/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3577850D1 publication Critical patent/DE3577850D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
DE8585107681T 1984-06-25 1985-06-21 Tetracyclische verbindungen, verfahren zu ihrer herstellung und eine diese enthaltende pharmazeutische zusammensetzung. Expired - Fee Related DE3577850D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848416141A GB8416141D0 (en) 1984-06-25 1984-06-25 Fr-900482 substance
GB858510378A GB8510378D0 (en) 1985-04-24 1985-04-24 Tetracyclo compounds

Publications (1)

Publication Number Publication Date
DE3577850D1 true DE3577850D1 (de) 1990-06-28

Family

ID=26287918

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585107681T Expired - Fee Related DE3577850D1 (de) 1984-06-25 1985-06-21 Tetracyclische verbindungen, verfahren zu ihrer herstellung und eine diese enthaltende pharmazeutische zusammensetzung.

Country Status (9)

Country Link
US (2) US4645765A (de)
EP (1) EP0166389B1 (de)
JP (3) JPH078872B1 (de)
KR (1) KR920009527B1 (de)
AU (1) AU584097B2 (de)
CA (1) CA1248897A (de)
DE (1) DE3577850D1 (de)
DK (1) DK170892B1 (de)
ES (2) ES8703477A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK733888A (da) * 1988-01-12 1989-07-13 Fujisawa Pharmaceutical Co Stabiliseringsmiddel
US4973693A (en) * 1989-09-01 1990-11-27 Shunsuke Goto Novel pentacyclic compound and stereoselective synthesis thereof
EP0943689A4 (de) 1996-10-29 2000-12-20 Fujisawa Pharmaceutical Co Verfahren zur herstellung von fr900482 und analoge verbindungen
JP2003171280A (ja) * 1999-06-07 2003-06-17 Fujisawa Pharmaceut Co Ltd 抗腫瘍効果増強剤
AU2001262731A1 (en) * 2000-06-20 2002-01-02 Fujisawa Pharmaceutical Co. Ltd. Tetracyclic compounds-containing pharmaceutical preparations
KR100768476B1 (ko) 2005-11-24 2007-10-18 한국해양연구원 항암물질을 생산하는 방선균 스트렙토마이세스 속 균주,이의 분리방법, 이로부터 반고형 추출물을 제조하는 방법,이로부터 유래한 반고형 추출물 및 이를 이용한 항암제조성물
CA2922452A1 (en) * 2013-08-29 2015-03-05 Seed Research Institute Co., Ltd. Novel microbial product having antifungal activity
CN111793015B (zh) * 2020-07-14 2021-08-27 遵义医科大学 一种含氮三元环化合物Strepmycin A及其分离方法和抗菌应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB974168A (en) * 1961-06-26 1964-11-04 Ici Ltd Manufacture of 2-ª‰-methoxyethylpyridine
US4313935A (en) * 1979-03-05 1982-02-02 Fujisawa Pharmaceutical Co., Ltd. Antibiotic FR-900129 substance, a process for the preparation thereof and pharmaceutical compositions containing the same
JPS56128774A (en) * 1980-03-14 1981-10-08 Microbial Chem Res Found New physiologically active substance ebelactone and its preparation

Also Published As

Publication number Publication date
JPH0767623A (ja) 1995-03-14
DK285585A (da) 1985-12-26
EP0166389B1 (de) 1990-05-23
AU4372885A (en) 1986-01-02
JPH01199975A (ja) 1989-08-11
DK170892B1 (da) 1996-03-04
ES8703477A1 (es) 1987-02-16
JPH078872B1 (de) 1995-02-01
CA1248897A (en) 1989-01-17
EP0166389A1 (de) 1986-01-02
KR860000385A (ko) 1986-01-28
ES544482A0 (es) 1987-02-16
AU584097B2 (en) 1989-05-18
KR920009527B1 (ko) 1992-10-17
DK285585D0 (da) 1985-06-24
JPH07102128B2 (ja) 1995-11-08
ES552029A0 (es) 1987-09-01
US4743555A (en) 1988-05-10
US4645765A (en) 1987-02-24
ES8707961A1 (es) 1987-09-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee