DE3575071D1 - Epipodophyllotoxinchinon-glukosid-abkoemmlinge, verfahren zur herstellung und verwendung. - Google Patents

Epipodophyllotoxinchinon-glukosid-abkoemmlinge, verfahren zur herstellung und verwendung.

Info

Publication number
DE3575071D1
DE3575071D1 DE8585903158T DE3575071T DE3575071D1 DE 3575071 D1 DE3575071 D1 DE 3575071D1 DE 8585903158 T DE8585903158 T DE 8585903158T DE 3575071 T DE3575071 T DE 3575071T DE 3575071 D1 DE3575071 D1 DE 3575071D1
Authority
DE
Germany
Prior art keywords
epipodophyllotoxinquinone
production
combination blades
glucoside
glucoside combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585903158T
Other languages
English (en)
Inventor
Josef Nemec
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
St Jude Childrens Research Hospital
Original Assignee
St Jude Childrens Research Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St Jude Childrens Research Hospital filed Critical St Jude Childrens Research Hospital
Application granted granted Critical
Publication of DE3575071D1 publication Critical patent/DE3575071D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8585903158T 1984-06-15 1985-06-14 Epipodophyllotoxinchinon-glukosid-abkoemmlinge, verfahren zur herstellung und verwendung. Expired - Fee Related DE3575071D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/620,844 US4609644A (en) 1984-06-15 1984-06-15 Epipodophyllotoxinquinone glucoside derivatives, method of production and use
PCT/US1985/001123 WO1986000018A1 (en) 1984-06-15 1985-06-14 Epipodophyllotoxinquinone glucoside derivatives method of production and use

Publications (1)

Publication Number Publication Date
DE3575071D1 true DE3575071D1 (de) 1990-02-08

Family

ID=24487649

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585903158T Expired - Fee Related DE3575071D1 (de) 1984-06-15 1985-06-14 Epipodophyllotoxinchinon-glukosid-abkoemmlinge, verfahren zur herstellung und verwendung.

Country Status (6)

Country Link
US (1) US4609644A (de)
EP (1) EP0185740B1 (de)
JP (1) JPS61502606A (de)
CA (1) CA1244013A (de)
DE (1) DE3575071D1 (de)
WO (1) WO1986000018A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61189230A (ja) * 1985-02-19 1986-08-22 Nippon Kayaku Co Ltd エトポシド製剤
IL77334A (en) * 1985-12-16 1991-04-15 Univ Bar Ilan Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor
US4916217A (en) * 1987-01-08 1990-04-10 Bristol-Myers Company Phosphorus containing derivatives of epipodophyllotoxin
US4853467A (en) * 1987-05-19 1989-08-01 Bristol-Myers Company Nitrogen containing derivatives of epipodophyllotoxin glucosides
US4874851A (en) * 1987-07-01 1989-10-17 Bristol-Meyers Company 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives
US4868291A (en) * 1987-08-20 1989-09-19 Bristol-Myers Company 4'-deshydroxyepipodophyllotoxin glucosides: synthesis and use
US4888419A (en) * 1987-08-31 1989-12-19 Bristol-Myers Company 3'-demethoxyepipodophyllotoxin glucoside derivatives
US4935504A (en) * 1987-12-18 1990-06-19 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-acyl derivatives
ZA886810B (en) * 1987-12-18 1989-08-30 Bristol Myers Co Epipodophyllotoxin glucoside 4'-acyl derivatives
JPH02191279A (ja) * 1988-10-26 1990-07-27 Warner Lambert Co ４‐ブロモ‐４′‐デメチルエピポドフイロトキシンおよびその新規な誘導体の製法
US5061791A (en) * 1988-12-21 1991-10-29 Warner-Lambert Company 4-bromo-4'-demethylepipodophyllotoxin derivatives
US4965348A (en) * 1989-05-19 1990-10-23 Bristol-Myers Company Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
FR2658824B1 (fr) * 1990-02-27 1992-07-03 Pf Medicament Tris acetyl-2",3",4' ethylidene-4",6" beta-d-glucopyranosides, leur preparation et leur utilisation pour la preparation d'ethylidene beta-d-glucopyranoside de demethyl-4' epipodophyllotoxine.
US6284789B1 (en) 1998-09-04 2001-09-04 The Research Foundation Of State University Of New York Formation and composition of new optically active compounds
BR112012033295A2 (pt) 2010-07-02 2016-10-11 Angiochem Inc polipeptídeos curtos e contendo d-aminoácido para conjugados terapêuticos e seu uso

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6613143A (de) * 1965-09-21 1967-03-22
CH464957A (de) * 1965-12-14 1968-11-15 Sandoz Ag Verfahren zur Herstellung eines neuen Glucosids
SE325409B (de) * 1967-12-22 1970-06-29 Bofors Ab
US3632802A (en) * 1968-12-06 1972-01-04 Univ Southern Illinois Oxidation of carbohydrates
US3755118A (en) * 1970-01-05 1973-08-28 J Partridge Process for preparing loganin and analogs thereof

Also Published As

Publication number Publication date
WO1986000018A1 (en) 1986-01-03
JPS61502606A (ja) 1986-11-13
US4609644A (en) 1986-09-02
EP0185740B1 (de) 1990-01-03
EP0185740A4 (de) 1986-08-21
CA1244013A (en) 1988-11-01
EP0185740A1 (de) 1986-07-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee