DE3572807D1 - A phenylpiperidine derivative, and its salts, their preparation, compositions containing them, and their therapeutic use - Google Patents
A phenylpiperidine derivative, and its salts, their preparation, compositions containing them, and their therapeutic useInfo
- Publication number
- DE3572807D1 DE3572807D1 DE8585300793T DE3572807T DE3572807D1 DE 3572807 D1 DE3572807 D1 DE 3572807D1 DE 8585300793 T DE8585300793 T DE 8585300793T DE 3572807 T DE3572807 T DE 3572807T DE 3572807 D1 DE3572807 D1 DE 3572807D1
- Authority
- DE
- Germany
- Prior art keywords
- salts
- preparation
- compositions containing
- therapeutic use
- phenylpiperidine derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Liquid Crystal Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/577,844 US4585777A (en) | 1984-02-07 | 1984-02-07 | (-)-Trans-4-(4-fluorophenyl)-3-(4-methoxyphenoxy)methylpiperidine for potentiating 5-HT |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3572807D1 true DE3572807D1 (en) | 1989-10-12 |
Family
ID=24310381
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8585300793T Expired DE3572807D1 (en) | 1984-02-07 | 1985-02-06 | A phenylpiperidine derivative, and its salts, their preparation, compositions containing them, and their therapeutic use |
Country Status (12)
Country | Link |
---|---|
US (1) | US4585777A (de) |
EP (1) | EP0152273B1 (de) |
JP (1) | JPS60181071A (de) |
AT (1) | ATE46146T1 (de) |
CA (1) | CA1246082A (de) |
DE (1) | DE3572807D1 (de) |
DK (1) | DK53285A (de) |
ES (1) | ES8601131A1 (de) |
FI (1) | FI850449L (de) |
GR (1) | GR850309B (de) |
IE (1) | IE850286L (de) |
NO (1) | NO850444L (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0223334B1 (de) * | 1985-08-10 | 1991-07-10 | Beecham Group Plc | Verfahren zur Herstellung von Arylpiperidincarbinol |
IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
GB8626936D0 (en) * | 1986-11-11 | 1986-12-10 | Ferrosan As | Treatment |
HU221921B1 (hu) * | 1996-07-08 | 2003-02-28 | Richter Gedeon Vegyészeti Gyár Rt. | N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására |
GB9623359D0 (en) * | 1996-11-09 | 1997-01-08 | Smithkline Beecham Plc | Novel process |
GB9700690D0 (en) | 1997-01-15 | 1997-03-05 | Smithkline Beecham Plc | Novel process |
AU7708998A (en) | 1997-05-29 | 1998-12-30 | Smithkline Beecham Corporation | Novel process |
PT994872E (pt) | 1997-06-10 | 2001-09-28 | Synthon Bv | Composto de 4-fenilpiperidina |
AU2002301956B2 (en) * | 1997-06-10 | 2006-02-09 | Synthon B.V. | 4-phenylpiperidine compounds |
CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
GB9914583D0 (en) * | 1999-06-22 | 1999-08-25 | Smithkline Beecham Plc | Novel process |
AU2000246280A1 (en) | 2000-05-12 | 2001-11-20 | Synthon B.V. | Tosylate salts of 4-(p-fluorophenyl)-piperidine-3-carbinols |
AU2001270858A1 (en) * | 2000-07-17 | 2002-01-30 | Smithkline Beecham Plc | Novel processes for the preparation of 4-phenylpiperidine derivatives |
WO2002028834A1 (en) * | 2000-10-06 | 2002-04-11 | Smithkline Beecham P.L.C. | Process for the preparation of aryl-piperidine carbinols and intermediates thereof |
US6777554B2 (en) | 2001-02-05 | 2004-08-17 | Teva Pharmaceutical Industries Ltd. | Preparation of N-methylparoxetine and related intermediate compounds |
NL1017421C2 (nl) * | 2001-02-21 | 2002-01-15 | Synthon Bv | Werkwijze voor het vervaardigen van paroxetine. |
US6930186B2 (en) | 2001-06-13 | 2005-08-16 | Teva Pharmacetical Industries Ltd. | Process for the preparation of paroxetine substantially free of alkoxy impurities |
US20070142389A1 (en) * | 2005-12-20 | 2007-06-21 | Pfizer Inc. | Piperidine derivatives |
EP2727915B1 (de) * | 2007-09-13 | 2016-04-13 | Concert Pharmaceuticals Inc. | Synthese von deuterierten Catecholen und Benzo[D][1,3]dioxolen und Derivate davon |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
-
1984
- 1984-02-07 US US06/577,844 patent/US4585777A/en not_active Expired - Lifetime
-
1985
- 1985-01-07 CA CA000471622A patent/CA1246082A/en not_active Expired
- 1985-02-04 GR GR850309A patent/GR850309B/el unknown
- 1985-02-04 FI FI850449A patent/FI850449L/fi not_active Application Discontinuation
- 1985-02-06 JP JP60020218A patent/JPS60181071A/ja active Granted
- 1985-02-06 DE DE8585300793T patent/DE3572807D1/de not_active Expired
- 1985-02-06 EP EP85300793A patent/EP0152273B1/de not_active Expired
- 1985-02-06 ES ES540172A patent/ES8601131A1/es not_active Expired
- 1985-02-06 NO NO850444A patent/NO850444L/no unknown
- 1985-02-06 AT AT85300793T patent/ATE46146T1/de not_active IP Right Cessation
- 1985-02-06 IE IE850286A patent/IE850286L/xx unknown
- 1985-02-06 DK DK53285A patent/DK53285A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DK53285D0 (da) | 1985-02-06 |
IE850286L (en) | 1985-08-07 |
EP0152273A3 (en) | 1986-12-30 |
ES540172A0 (es) | 1985-11-16 |
US4585777A (en) | 1986-04-29 |
EP0152273A2 (de) | 1985-08-21 |
ATE46146T1 (de) | 1989-09-15 |
JPS60181071A (ja) | 1985-09-14 |
NO850444L (no) | 1985-08-08 |
JPS6135176B2 (de) | 1986-08-12 |
ES8601131A1 (es) | 1985-11-16 |
CA1246082A (en) | 1988-12-06 |
DK53285A (da) | 1985-08-08 |
FI850449L (fi) | 1985-08-08 |
FI850449A0 (fi) | 1985-02-04 |
EP0152273B1 (de) | 1989-09-06 |
GR850309B (de) | 1985-06-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |