DE3561818D1 - Isoxazoloquinolinone derivatives, process and intermediates for their preparation, use as medicaments and compositions containing them - Google Patents
Isoxazoloquinolinone derivatives, process and intermediates for their preparation, use as medicaments and compositions containing themInfo
- Publication number
- DE3561818D1 DE3561818D1 DE8585401234T DE3561818T DE3561818D1 DE 3561818 D1 DE3561818 D1 DE 3561818D1 DE 8585401234 T DE8585401234 T DE 8585401234T DE 3561818 T DE3561818 T DE 3561818T DE 3561818 D1 DE3561818 D1 DE 3561818D1
- Authority
- DE
- Germany
- Prior art keywords
- carbon atoms
- radical containing
- isoxazoloquinolinone
- derivatives
- medicaments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- IXQREGLIGLUSKL-UHFFFAOYSA-N 1H-[1,2]oxazolo[3,4-h]quinolin-2-one Chemical class C1=CC2=NOC=C2C2=C1C=CC(=O)N2 IXQREGLIGLUSKL-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- -1 alkyl radical Chemical class 0.000 abstract 6
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical group ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- WZKSXHQDXQKIQJ-UHFFFAOYSA-N F[C](F)F Chemical compound F[C](F)F WZKSXHQDXQKIQJ-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Lubricants (AREA)
- Color Television Systems (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8409961A FR2566407B1 (fr) | 1984-06-25 | 1984-06-25 | Nouveaux derives de l'isoxazoloquinoleine, procede de preparation, application a titre de medicaments, et compositions les renfermant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3561818D1 true DE3561818D1 (en) | 1988-04-14 |
Family
ID=9305387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8585401234T Expired DE3561818D1 (en) | 1984-06-25 | 1985-06-20 | Isoxazoloquinolinone derivatives, process and intermediates for their preparation, use as medicaments and compositions containing them |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0168309B1 (en, 2012) |
| JP (1) | JPS6176491A (en, 2012) |
| KR (1) | KR860000296A (en, 2012) |
| AT (1) | ATE32899T1 (en, 2012) |
| CA (1) | CA1225993A (en, 2012) |
| DE (1) | DE3561818D1 (en, 2012) |
| DK (1) | DK284085A (en, 2012) |
| ES (1) | ES8604599A1 (en, 2012) |
| FI (1) | FI79322C (en, 2012) |
| FR (1) | FR2566407B1 (en, 2012) |
| GR (1) | GR851530B (en, 2012) |
| HU (1) | HU192234B (en, 2012) |
| IL (1) | IL75562A (en, 2012) |
| MA (1) | MA20461A1 (en, 2012) |
| NZ (1) | NZ212532A (en, 2012) |
| OA (1) | OA08045A (en, 2012) |
| PT (1) | PT80690B (en, 2012) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4920117A (en) * | 1989-06-09 | 1990-04-24 | Hoechst-Roussel Pharmaceuticals Inc. | 4,5,5a,6-tetrahydro-3H-isoxazolo(5,4,3-kl)acridines, pharmaceutical compositions and use |
| US5182290A (en) * | 1991-08-27 | 1993-01-26 | Neurogen Corporation | Certain oxazoloquinolinones; a new class of GABA brain receptor ligands |
| CA2258822A1 (en) * | 1996-06-20 | 1997-12-24 | Sean Kerwin | Compounds and methods for providing pharmacologically active preparations and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2537140B1 (fr) * | 1982-12-07 | 1986-07-18 | Roussel Uclaf | Nouveaux derives de la 4-hydroxy-3-quinoleine carboxamide, leur sels, procede de preparation, application a titre de medicaments, et compositions les renfermant |
-
1984
- 1984-06-25 FR FR8409961A patent/FR2566407B1/fr not_active Expired
-
1985
- 1985-06-05 FI FI852249A patent/FI79322C/fi not_active IP Right Cessation
- 1985-06-19 IL IL75562A patent/IL75562A/xx unknown
- 1985-06-20 AT AT85401234T patent/ATE32899T1/de active
- 1985-06-20 DE DE8585401234T patent/DE3561818D1/de not_active Expired
- 1985-06-20 EP EP85401234A patent/EP0168309B1/fr not_active Expired
- 1985-06-21 CA CA000484819A patent/CA1225993A/fr not_active Expired
- 1985-06-24 PT PT80690A patent/PT80690B/pt not_active IP Right Cessation
- 1985-06-24 DK DK284085A patent/DK284085A/da not_active Application Discontinuation
- 1985-06-24 MA MA20688A patent/MA20461A1/fr unknown
- 1985-06-24 JP JP60136225A patent/JPS6176491A/ja active Pending
- 1985-06-24 ES ES544488A patent/ES8604599A1/es not_active Expired
- 1985-06-24 NZ NZ212532A patent/NZ212532A/xx unknown
- 1985-06-24 HU HU852472A patent/HU192234B/hu not_active IP Right Cessation
- 1985-06-24 GR GR851530A patent/GR851530B/el unknown
- 1985-06-25 OA OA58619A patent/OA08045A/xx unknown
- 1985-06-25 KR KR1019850004504A patent/KR860000296A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP0168309B1 (fr) | 1988-03-09 |
| GR851530B (en, 2012) | 1985-11-25 |
| PT80690B (fr) | 1987-03-31 |
| HUT38948A (en) | 1986-07-28 |
| EP0168309A1 (fr) | 1986-01-15 |
| ES8604599A1 (es) | 1986-02-01 |
| FR2566407A1 (fr) | 1985-12-27 |
| DK284085A (da) | 1985-12-26 |
| KR860000296A (ko) | 1986-01-27 |
| FI79322B (fi) | 1989-08-31 |
| ATE32899T1 (de) | 1988-03-15 |
| NZ212532A (en) | 1988-08-30 |
| MA20461A1 (fr) | 1985-12-31 |
| IL75562A0 (en) | 1985-10-31 |
| HU192234B (en) | 1987-05-28 |
| FI79322C (fi) | 1989-12-11 |
| JPS6176491A (ja) | 1986-04-18 |
| ES544488A0 (es) | 1986-02-01 |
| CA1225993A (fr) | 1987-08-25 |
| FI852249L (fi) | 1985-12-26 |
| PT80690A (fr) | 1985-07-01 |
| FI852249A0 (fi) | 1985-06-05 |
| IL75562A (en) | 1988-07-31 |
| OA08045A (fr) | 1987-01-31 |
| DK284085D0 (da) | 1985-06-24 |
| FR2566407B1 (fr) | 1986-09-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |