DE3561551D1 - Anti-hypertensive octahydro-6-azaindole dipeptide derivatives - Google Patents

Anti-hypertensive octahydro-6-azaindole dipeptide derivatives

Info

Publication number
DE3561551D1
DE3561551D1 DE8585309229T DE3561551T DE3561551D1 DE 3561551 D1 DE3561551 D1 DE 3561551D1 DE 8585309229 T DE8585309229 T DE 8585309229T DE 3561551 T DE3561551 T DE 3561551T DE 3561551 D1 DE3561551 D1 DE 3561551D1
Authority
DE
Germany
Prior art keywords
azaindole
octahydro
hypertensive
dipeptide derivatives
dipeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8585309229T
Other languages
English (en)
Inventor
Simon Fraser Dr Campbell
Ryszard Jurek Dr Kobylecki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Pfizer Corp
Original Assignee
Pfizer Ltd
Pfizer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848432532A external-priority patent/GB8432532D0/en
Priority claimed from GB858514634A external-priority patent/GB8514634D0/en
Application filed by Pfizer Ltd, Pfizer Corp filed Critical Pfizer Ltd
Application granted granted Critical
Publication of DE3561551D1 publication Critical patent/DE3561551D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
DE8585309229T 1984-12-21 1985-12-18 Anti-hypertensive octahydro-6-azaindole dipeptide derivatives Expired DE3561551D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848432532A GB8432532D0 (en) 1984-12-21 1984-12-21 Therapeutic agents
GB858514634A GB8514634D0 (en) 1985-06-10 1985-06-10 Therapeutic agents

Publications (1)

Publication Number Publication Date
DE3561551D1 true DE3561551D1 (de) 1988-03-10

Family

ID=26288610

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585309229T Expired DE3561551D1 (de) 1984-12-21 1985-12-18 Anti-hypertensive octahydro-6-azaindole dipeptide derivatives

Country Status (16)

Country Link
US (1) US4711882A (de)
EP (1) EP0186431B1 (de)
CN (1) CN85109243A (de)
AU (1) AU558427B2 (de)
CS (1) CS250699B2 (de)
DE (1) DE3561551D1 (de)
DK (1) DK595385A (de)
ES (1) ES8702923A1 (de)
FI (1) FI855112A (de)
GR (1) GR853117B (de)
HU (1) HUT40125A (de)
NO (1) NO855214L (de)
NZ (1) NZ214649A (de)
PL (1) PL256935A1 (de)
PT (1) PT81722B (de)
YU (1) YU199485A (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
FR2487829A2 (fr) * 1979-12-07 1982-02-05 Science Union & Cie Nouveaux imino acides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
EP0050800B2 (de) * 1980-10-23 1995-06-07 Schering Corporation Carboxyalkyl-Dipeptide, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE3302125A1 (de) * 1983-01-22 1984-07-26 Boehringer Ingelheim KG, 6507 Ingelheim Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung

Also Published As

Publication number Publication date
ES8702923A1 (es) 1987-01-16
CS250699B2 (en) 1987-05-14
AU5151285A (en) 1986-06-26
PL256935A1 (en) 1987-02-23
EP0186431A1 (de) 1986-07-02
PT81722B (en) 1987-10-19
FI855112A (fi) 1986-06-22
DK595385A (da) 1986-06-22
EP0186431B1 (de) 1988-02-03
NO855214L (no) 1986-06-23
FI855112A0 (fi) 1985-12-20
CN85109243A (zh) 1986-09-17
AU558427B2 (en) 1987-01-29
NZ214649A (en) 1988-02-12
US4711882A (en) 1987-12-08
ES550149A0 (es) 1987-01-16
YU199485A (en) 1988-04-30
DK595385D0 (da) 1985-12-20
GR853117B (de) 1986-04-22
HUT40125A (en) 1986-11-28
PT81722A (en) 1986-01-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee