DE3475706D1 - Iron iii complexes of hydroxypyridones, and their pharmaceutical compositions - Google Patents

Iron iii complexes of hydroxypyridones, and their pharmaceutical compositions

Info

Publication number
DE3475706D1
DE3475706D1 DE8484301882T DE3475706T DE3475706D1 DE 3475706 D1 DE3475706 D1 DE 3475706D1 DE 8484301882 T DE8484301882 T DE 8484301882T DE 3475706 T DE3475706 T DE 3475706T DE 3475706 D1 DE3475706 D1 DE 3475706D1
Authority
DE
Germany
Prior art keywords
hydroxypyridones
pharmaceutical compositions
iron iii
iii complexes
complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484301882T
Other languages
English (en)
Inventor
Robert Charles Hider
George Kontoghiorghes
Jack Silver
Michael Arthur Stockham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
National Research Development Corp UK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Research Development Corp UK filed Critical National Research Development Corp UK
Application granted granted Critical
Publication of DE3475706D1 publication Critical patent/DE3475706D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/69—Two or more oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8484301882T 1983-03-24 1984-03-20 Iron iii complexes of hydroxypyridones, and their pharmaceutical compositions Expired DE3475706D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838308055A GB8308055D0 (en) 1983-03-24 1983-03-24 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
DE3475706D1 true DE3475706D1 (en) 1989-01-26

Family

ID=10540099

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484301882T Expired DE3475706D1 (en) 1983-03-24 1984-03-20 Iron iii complexes of hydroxypyridones, and their pharmaceutical compositions

Country Status (9)

Country Link
US (2) US4650793A (de)
EP (1) EP0120670B1 (de)
JP (1) JPH0625120B2 (de)
CY (1) CY1504A (de)
DE (1) DE3475706D1 (de)
DK (1) DK159305C (de)
GB (2) GB8308055D0 (de)
HK (1) HK5190A (de)
SG (1) SG54389G (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4912118A (en) * 1983-09-23 1990-03-27 National Research Development Corporation Pharmaceutical compositions
GB8329043D0 (en) * 1983-10-31 1983-11-30 Hider R C Pharmaceutical compositions
US5177068A (en) * 1984-04-19 1993-01-05 National Research Development Corporation Pharmaceutical compositions
GB8410289D0 (en) * 1984-04-19 1984-05-31 Callingham B A Pharmaceutical compositions
DE3826846A1 (de) * 1988-08-06 1990-02-08 Goedecke Ag Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
GB9006522D0 (en) * 1990-03-23 1990-05-23 Hider Robert C Metal complexes
GB9209078D0 (en) * 1992-04-27 1992-06-10 Hider Robert C Pharmaceutical compositions
GB9217099D0 (en) * 1992-08-12 1992-09-23 British Tech Group Pharmaceutical compositions
EP0833627B1 (de) 1995-06-10 2004-08-18 Vitra Pharmaceuticals Ltd. Eisenverbindungen, zusammensetzungen, herstellungsverfahren und verwendungen davon
DE69607099T2 (de) 1995-10-06 2000-12-14 Calgon Corp Verwendung von synergischer Zusammensetzung für die Kontrolle von Kesselstein
GB9625638D0 (en) * 1996-12-10 1997-01-29 Cenes Ltd Therapeutic antioxidants for alzheimer's diease
GB9723078D0 (en) * 1997-10-31 1998-01-07 Cerebrus Ltd Chemical compounds
US6294152B1 (en) * 1999-01-11 2001-09-25 The University Of Toledo Iron(III) complexes as contrast agents for image enhancement in magnetic resonance imaging
US6767741B1 (en) * 1999-08-27 2004-07-27 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
DE60107272T2 (de) * 2000-09-19 2005-10-27 Vitra Pharmaceuticals Ltd., Saffron Walden Eisenverbindungen
GB0211500D0 (en) * 2002-05-18 2002-06-26 Vitra Pharmaceuticals Ltd Method of forming iron hydroxypyrone compounds
US8026261B2 (en) 2007-03-28 2011-09-27 Apotex Technologies Inc. Fluorinated derivatives of deferiprone
DK2268282T3 (en) 2008-04-25 2014-11-24 Apotex Technologies Inc Liquid formulation of deferiprone with pleasant taste
SI2448922T1 (sl) 2009-07-03 2014-12-31 Apotex Technologies Inc. Fluorirani derivati 3-hidroksipiridin-4-onov
GB201101370D0 (en) 2011-01-27 2011-03-09 Iron Therapeutics Holdings Ag Process
US9439910B2 (en) 2012-04-05 2016-09-13 Vifor (International) Ag Fe(III)-pyrazine complex compounds for treatment and prophylaxis of iron-deficiency phenomena and iron-deficiency anaemia

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US34313A (en) * 1862-02-04 Improvement in ladders and staging for artisans
US3016372A (en) * 1956-12-13 1962-01-09 Searle & Co Glycosides of the pyridone series
AR207322A1 (es) * 1972-12-18 1976-09-30 Merck & Co Inc Procedimiento para preparar complejos de 4,4'-dinitrocarbanilidas con derivados de piridonas 2-y 4-substituidas pirimidin-2-y-6-/nas y tetrahidroquinolonas utiles para la prevencion y tratamiento da la coccidiosis
JPS5953261B2 (ja) * 1973-08-03 1984-12-24 明治製菓株式会社 ２（１ｈ）−ピリドン誘導体の製造法
EP0094149B1 (de) * 1982-03-24 1986-09-10 National Research Development Corporation Pharmazeutische Zusammensetzungen, die Eisen-Komplexe von N-substituierten 3-Hydroxypyrid-2-on- oder -4-on-Derivaten enthalten
GR78491B (de) * 1982-03-24 1984-09-27 Nat Res Dev
GB2118176B (en) * 1982-03-24 1985-12-04 Nat Res Dev Pharmaceutical compositions
GB2117766B (en) * 1982-03-24 1985-08-29 Nat Res Dev Pharmaceutical compositions
JPS59118792A (ja) * 1982-12-24 1984-07-09 Kyowa Hakko Kogyo Co Ltd セフエム化合物
GB8325494D0 (en) * 1983-09-23 1983-10-26 Hider R C Pharmaceutical compositions
USRE34313E (en) 1983-09-23 1993-07-13 National Research Development Corporation Pharmaceutical compositions
US4912118A (en) * 1983-09-23 1990-03-27 National Research Development Corporation Pharmaceutical compositions
GB8325496D0 (en) * 1983-09-23 1983-10-26 Hider R C Pharmaceutical compositions
US5177068A (en) * 1984-04-19 1993-01-05 National Research Development Corporation Pharmaceutical compositions

Also Published As

Publication number Publication date
JPH0625120B2 (ja) 1994-04-06
DK165984D0 (da) 1984-03-23
GB2136806A (en) 1984-09-26
DK159305C (da) 1991-03-04
DK165984A (da) 1984-09-25
US4650793A (en) 1987-03-17
USRE36831E (en) 2000-08-22
EP0120670B1 (de) 1988-12-21
SG54389G (en) 1989-12-08
HK5190A (en) 1990-02-02
GB2136806B (en) 1987-04-15
GB8308055D0 (en) 1983-05-05
CY1504A (en) 1990-08-03
DK159305B (da) 1990-10-01
GB8407180D0 (en) 1984-04-26
JPS59181258A (ja) 1984-10-15
EP0120670A1 (de) 1984-10-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BRITISH TECHNOLOGY GROUP LTD., LONDON, GB

8328 Change in the person/name/address of the agent

Free format text: DEUFEL, P., DIPL.-WIRTSCH.-ING.DR.RER.NAT. HERTEL, W., DIPL.-PHYS. RUTETZKI, A., DIPL.-ING.UNIV. RUCKER, E., DIPL.-CHEM. UNIV. DR.RER.NAT. HUBER, B., DIPL.-BIOL. DR.RER.NAT. BECKER, E., DR.RER.NAT., 80331 MUENCHEN KURIG, T., DIPL.-PHYS., 83022 ROSENHEIM STEIL, C., DIPL.-ING., PAT.-ANWAELTE, 80331 MUENCHEN

8339 Ceased/non-payment of the annual fee