DE3475402D1 - Endo-8,8-dialkyl-8-azoniabicyclo (3.2.1) octane-6,7-exo-epoxy-3-alkyl-carboxylate salts, a process for their preparation, and therapeutic compositions which contain them as active principle - Google Patents

Endo-8,8-dialkyl-8-azoniabicyclo (3.2.1) octane-6,7-exo-epoxy-3-alkyl-carboxylate salts, a process for their preparation, and therapeutic compositions which contain them as active principle

Info

Publication number
DE3475402D1
DE3475402D1 DE8484107838T DE3475402T DE3475402D1 DE 3475402 D1 DE3475402 D1 DE 3475402D1 DE 8484107838 T DE8484107838 T DE 8484107838T DE 3475402 T DE3475402 T DE 3475402T DE 3475402 D1 DE3475402 D1 DE 3475402D1
Authority
DE
Germany
Prior art keywords
sub
azoniabicyclo
exo
octane
dialkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484107838T
Other languages
German (de)
English (en)
Inventor
Maurizio Fano
Roberto Margutti
Fausto Bonifacio
Virgilio Bernareggi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Valeas SpA Industria Chimica e Farmaceutica
Original Assignee
Valeas SpA Industria Chimica e Farmaceutica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valeas SpA Industria Chimica e Farmaceutica filed Critical Valeas SpA Industria Chimica e Farmaceutica
Application granted granted Critical
Publication of DE3475402D1 publication Critical patent/DE3475402D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8484107838T 1983-07-26 1984-07-05 Endo-8,8-dialkyl-8-azoniabicyclo (3.2.1) octane-6,7-exo-epoxy-3-alkyl-carboxylate salts, a process for their preparation, and therapeutic compositions which contain them as active principle Expired DE3475402D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22238/83A IT1194343B (it) 1983-07-26 1983-07-26 Sali di endo-8,8-dialchil-8-azoniabiciclo (3.2.1) ottan-6,7-esso-epossi-3-alchilcarbossilati,processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo

Publications (1)

Publication Number Publication Date
DE3475402D1 true DE3475402D1 (en) 1989-01-05

Family

ID=11193504

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484107838T Expired DE3475402D1 (en) 1983-07-26 1984-07-05 Endo-8,8-dialkyl-8-azoniabicyclo (3.2.1) octane-6,7-exo-epoxy-3-alkyl-carboxylate salts, a process for their preparation, and therapeutic compositions which contain them as active principle

Country Status (11)

Country Link
US (1) US4558054A (enExample)
EP (1) EP0133218B1 (enExample)
JP (1) JPS6042382A (enExample)
AT (1) ATE38989T1 (enExample)
AU (1) AU562763B2 (enExample)
CA (1) CA1248956A (enExample)
DE (1) DE3475402D1 (enExample)
DK (1) DK162285C (enExample)
IT (1) IT1194343B (enExample)
NZ (1) NZ208857A (enExample)
ZA (1) ZA845308B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190133B (it) * 1986-06-19 1988-02-10 Chiesi Farma Spa Derivati di acido valproico e di acido (e)-2-valproenoico,procedimento per la loro preparazione e relative composizioni farmaceutiche
DE4108393A1 (de) * 1991-03-15 1992-09-17 Boehringer Ingelheim Kg Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln
US6706726B2 (en) * 2000-10-14 2004-03-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anticholinergics which may be used as medicaments as well as processes for preparing them
PE20060826A1 (es) * 2004-12-06 2006-10-08 Smithkline Beecham Corp Derivado oleofinico de 8-azoniabiciclo[3.2.1]octano y combinacion farmaceutica que lo comprende

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2962499A (en) * 1957-07-03 1960-11-29 Endo Lab Certain esters of tropine and tropinium salts
DE1795818C2 (de) * 1966-01-26 1980-07-10 C.H. Boehringer Sohn, 6507 Ingelheim Quartärsalze des N-Äthylnorscopolamin
DE1670048C3 (de) * 1966-01-26 1980-09-04 C.H. Boehringer Sohn, 6507 Ingelheim Neue Norscopolaminderivate
GB1413484A (en) * 1972-04-18 1975-11-12 Angeli Inst Spa Scopolamine derivatives
IT1140998B (it) * 1980-06-18 1986-10-10 Valeas Ind Chimica E Farmaceut Sali di endo-8-metil-8-sin-alchil-8-azoniabiciclo aperta par. quadrata 3.2.1. chiusa par. quadrata-ottan-3-alchilcarbossilati, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo

Also Published As

Publication number Publication date
DK363284D0 (da) 1984-07-25
AU3116384A (en) 1985-01-31
ATE38989T1 (de) 1988-12-15
IT8322238A1 (it) 1985-01-26
EP0133218A3 (en) 1986-12-30
DK363284A (da) 1985-01-27
ZA845308B (en) 1985-02-27
DK162285C (da) 1992-03-02
CA1248956A (en) 1989-01-17
EP0133218A2 (en) 1985-02-20
IT8322238A0 (it) 1983-07-26
DK162285B (da) 1991-10-07
US4558054A (en) 1985-12-10
JPH0331199B2 (enExample) 1991-05-02
JPS6042382A (ja) 1985-03-06
IT1194343B (it) 1988-09-14
NZ208857A (en) 1988-05-30
EP0133218B1 (en) 1988-11-30
AU562763B2 (en) 1987-06-18

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee